Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephanie A. Stehman"'
Publikováno v:
The Journal of Cell Biology
NudE and NudEL are related proteins that interact with cytoplasmic dynein and LIS1. Their functional relationship and involvement in LIS1 and dynein regulation are not completely understood. We find that NudE and NudEL each localize to mitotic kineto
Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function
Publikováno v:
The Journal of Cell Biology
Zeste white 10 (ZW10) is a mitotic checkpoint protein and the anchor for cytoplasmic dynein at mitotic kinetochores, though it is expressed throughout the cell cycle. We find that ZW10 localizes to pericentriolar membranous structures during interpha
Autor:
Gregg G. Gundersen, Stephanie A. Stehman, Edgar R. Gomes, Denis L. Dujardin, Lora E. Barnhart, Richard B. Vallee
Publikováno v:
The Journal of Cell Biology
Cytoplasmic dynein has been implicated in numerous aspects of intracellular movement. We recently found dynein inhibitors to interfere with the reorientation of the microtubule cytoskeleton during healing of wounded NIH3T3 cell monolayers. We now fin
Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment
Publikováno v:
The Journal of Cell Biology
Cytoplasmic dynein has been implicated in diverse mitotic functions, several involving its association with kinetochores. Much of the supporting evidence comes from inhibition of dynein regulatory factors. To obtain direct insight into kinetochore dy
Publikováno v:
Trends in cell biology. 15(6)
Cytoplasmic dynein is the major minus-end-directed microtubule motor protein in interphase cells. In addition to its well-established roles in vesicular transport and chromosome dynamics, cytoplasmic dynein also associates with the cell cortex. From