Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Stephanie A. Schultz"'
Autor:
Gengsheng Chen, Nicole S. McKay, Brian A. Gordon, Jingxia Liu, Nelly Joseph-Mathurin, Suzanne E. Schindler, Jason Hassenstab, Andrew J. Aschenbrenner, Qing Wang, Stephanie A. Schultz, Yi Su, Pamela J LaMontagne, Sarah J. Keefe, Parinaz Massoumzadeh, Carlos Cruchaga, Chengjie Xiong, John C. Morris, Tammie L.S. Benzinger
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103551- (2024)
The use of biomarkers for the early detection of Alzheimer’s disease (AD) is crucial for developing potential therapeutic treatments. Positron Emission Tomography (PET) is a well-established tool used to detect β-amyloid (Aβ) plaques in the brain
Externí odkaz:
https://doaj.org/article/55129f96597543b38eb932e438ce93d5
Autor:
Christine Rother, Ruth E. Uhlmann, Stephan A. Müller, Juliane Schelle, Angelos Skodras, Ulrike Obermüller, Lisa M. Häsler, Marius Lambert, Frank Baumann, Ying Xu, Carina Bergmann, Giulia Salvadori, Maarten Loos, Irena Brzak, Derya Shimshek, Ulf Neumann, Dominantly Inherited Alzheimer Network, Lary C. Walker, Stephanie A. Schultz, Jasmeer P. Chhatwal, Stephan A. Kaeser, Stefan F. Lichtenthaler, Matthias Staufenbiel, Mathias Jucker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The poor correlation between brain Aβ deposition and clinical symptoms in Alzheimer´s disease remains puzzling. Here, the authors show a temporal dissociation of Aβ deposition and neurodegeneration.
Externí odkaz:
https://doaj.org/article/c331575d738c441aa6d10bc637786581
Autor:
Gretchen Reynolds, Rachel Buckley, Kathryn Papp, Stephanie A. Schultz, Dorene Rentz, Reisa Sperling, Rebecca Amariglio
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction Subjective cognitive decline (SCD) has been associated with elevated amyloid levels and increased risk of future cognitive decline, as well as modifiable variables, including depression, anxiety, and physical inactivity. Partici
Externí odkaz:
https://doaj.org/article/65aabd2e114f4bc6bc732110b6f7b6e0
Autor:
Stephanie A. Schultz, Jennifer Byers, Tammie L. S. Benzinger, Dominic Reeds, Andrei G. Vlassenko, W. Todd Cade, Manu S. Goyal
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Cardiorespiratory fitness (CRF) is routinely investigated in diverse populations, including in older adults of varying physical activity levels. Commonly performed maximal exercise testing protocols might be contraindicated and/or inadequate for olde
Externí odkaz:
https://doaj.org/article/fe3c9d45cdbe4e67906108db01d08d9a
Autor:
Stephanie A. Schultz, Jeremy F. Strain, Adedamola Adedokun, Qing Wang, Oliver Preische, Jens Kuhle, Shaney Flores, Sarah Keefe, Aylin Dincer, Beau M. Ances, Sarah B. Berman, Adam M. Brickman, David M. Cash, Jasmeer Chhatwal, Carlos Cruchaga, Michael Ewers, Nick N. Fox, Bernardino Ghetti, Alison Goate, Neill R. Graff-Radford, Jason J. Hassenstab, Russ Hornbeck, Clifford Jack, Jr, Keith Johnson, Nelly Joseph-Mathurin, Celeste M. Karch, Robert A. Koeppe, Athene K.W. Lee, Johannes Levin, Colin Masters, Eric McDade, Richard J. Perrin, Christopher C. Rowe, Stephen Salloway, Andrew J. Saykin, Reisa Sperling, Yi Su, Victor L. Villemagne, Jonathan Vöglein, Michael Weiner, Chengjie Xiong, Anne M. Fagan, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger, Mathias Jucker, Brian A. Gordon
Publikováno v:
Neurobiology of Disease, Vol 142, Iss , Pp 104960- (2020)
Neurofilament light chain (NfL) is a protein that is selectively expressed in neurons. Increased levels of NfL measured in either cerebrospinal fluid or blood is thought to be a biomarker of neuronal damage in neurodegenerative diseases. However, the
Externí odkaz:
https://doaj.org/article/715a9dd1ef8d47e39b69d4c948b3a8f5
Autor:
Lena L. Law, Rachael N. Rol, Stephanie A. Schultz, Ryan J. Dougherty, Dorothy F. Edwards, Rebecca L. Koscik, Catherine L. Gallagher, Cynthia M. Carlsson, Barbara B. Bendlin, Henrik Zetterberg, Kaj Blennow, Sanjay Asthana, Mark A. Sager, Bruce P. Hermann, Sterling C. Johnson, Dane B. Cook, Ozioma C. Okonkwo
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 188-195 (2018)
Abstract Introduction Alzheimer's disease (AD) is characterized by the presence of amyloid β (Aβ) plaques, neurofibrillary tangles, and neurodegeneration, evidence of which may be detected in vivo via cerebrospinal fluid (CSF) sampling. Physical ac
Externí odkaz:
https://doaj.org/article/adab0326488e4404b6e0a16cb9ac2006
Autor:
Ryan J. Dougherty, Laura D. Ellingson, Stephanie A. Schultz, Elizabeth A. Boots, Jacob D. Meyer, Jacob B. Lindheimer, Stephanie Van Riper, Aaron J. Stegner, Dorothy F. Edwards, Jennifer M. Oh, Rebecca L. Koscik, Maritza N. Dowling, Catherine L. Gallagher, Cynthia M. Carlsson, Howard A. Rowley, Barbara B. Bendlin, Sanjay Asthana, Bruce P. Hermann, Mark A. Sager, Sterling C. Johnson, Ozioma C. Okonkwo, Dane B. Cook
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 4, Iss 1, Pp 14-17 (2016)
Abstract Introduction Physical activity (PA) is associated with brain health in older adults. However, it is unknown whether the current physical activity recommendations (PAR) impart substantive benefit. The objective of this study was to compare te
Externí odkaz:
https://doaj.org/article/4ca8080c33614257afd1baf2aefe2389
Autor:
Benjamin M. Doherty, Stephanie A. Schultz, Jennifer M. Oh, Rebecca L. Koscik, N. Maritza Dowling, Todd E. Barnhart, Dhanabalan Murali, Catherine L. Gallagher, Cynthia M. Carlsson, Barbara B. Bendlin, Asenath LaRue, Bruce P. Hermann, Howard A. Rowley, Sanjay Asthana, Mark A. Sager, Brad T. Christian, Sterling C. Johnson, Ozioma C. Okonkwo
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 2, Pp 160-169 (2015)
Abstract There is a growing interest in understanding how amyloid β (Aβ) accumulation in preclinical Alzheimer's disease relates to brain morphometric measures and cognition. Existing investigations in this area have been primarily conducted in old
Externí odkaz:
https://doaj.org/article/565826ad3ce34a42bd65a431046cfc55
Autor:
Stephanie A. Schultz, Jennifer M. Oh, Rebecca L. Koscik, N. Maritza Dowling, Catherine L. Gallagher, Cynthia M. Carlsson, Barbara B. Bendlin, Asenath LaRue, Bruce P. Hermann, Howard A. Rowley, Sanjay Asthana, Mark A. Sager, Sterling C. Johnson, Ozioma C. Okonkwo
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 1, Pp 33-40 (2015)
Abstract Background Subjective memory complaints (SMCs) represent an individual's perception of subtle changes in memory in the absence of objective impairment in memory. However, it is not fully known whether persons with SMCs harbor brain alteratio
Externí odkaz:
https://doaj.org/article/f72e5ed0a0264eaf87027e36eacd2daa
Autor:
Gengsheng Chen, Nicole S. McKay, Brian A. Gordon, Jingxia Liu, Nelly Joseph-Mathurin, Suzanne Schindler, Jason Hassenstab, Andrew J. Aschenbrenner, Qing Wang, Stephanie A. Schultz, Yi Su, Pamela J. LaMontagne, Sarah J. Keefe, Parinaz Massoumzadeh, Carlos Cruchaga, John C. Morris, Tammie Benzinger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0efa332cc51eb5547b1d6a3c6137d1
https://doi.org/10.2139/ssrn.4348547
https://doi.org/10.2139/ssrn.4348547