Výsledky vyhledávání - "Stephanie A. Rock"

Akademický článek

Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent MannerSummary

Autor: Stephanie A. Rock, Kai Jiang, Yuanyuan Wu, Yajuan Liu, Jing Li, Heidi L. Weiss, Chi Wang, Jianhang Jia, Tianyan Gao, B. Mark Evers

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 501-516 (2022)

Background & Aims: Intestinal stem cells (ISCs) are sensitive to dietary alterations and nutrient availability. Neurotensin (NT), a gut peptide localized predominantly to the small bowel and released by fat ingestion, stimulates the growth of intesti

Externí odkaz: https://doaj.org/article/8b1d14a0e12e48ed95e13d135d68e993

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Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner

Autor: Heidi L. Weiss, Stephanie A. Rock, Tianyan Gao, Chi Wang, Jing Li, B. Mark Evers, Yuanyuan Wu, Kai Jiang, Yajuan Liu, Jianhang Jia

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 501-516 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b829f42bc7cc4f64577e8588c520793
https://doi.org/10.1016/j.jcmgh.2021.09.006

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Absence of neurotensin attenuates intestinal dysbiosis and inflammation by maintaining Mmp7/α-defensin axis in diet-induced obese mice

Autor: Chi Wang, Jinpeng Liu, Xian Li, Jianhang Jia, Tianyan Gao, Jun Song, Ashfaqul Alam, Jing Li, B. Mark Evers, Baoxiang Yan, Todd Weiss, Heidi L. Weiss, Stephanie A. Rock

Publikováno v: FASEB J

We previously reported that high levels of plasma neurotensin (NT), a gut hormone released from enteroendocrine cells of the small bowel, contribute to obesity and comorbid conditions. Gut microbiota has been implicated in the obesity development. Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61891603b108586ae4350cab20bf86f
https://europepmc.org/articles/PMC7754978/

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Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling

Autor: Courtney M. Townsend, Piotr G. Rychahou, Stephanie B. Rock, Jing Li, B. Mark Evers, Heidi L. Weiss, Xian Li, Jun Song, Tianyan Gao

Publikováno v: PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0211134 (2019)

Neurotensin is a peptide hormone released from enteroendocrine cells in the small intestine in response to fat ingestion. Although the mechanisms regulating neurotensin secretion are still incompletely understood, our recent findings implicate a role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390d8340b354ff7cd5b89143f7058dad
https://pubmed.ncbi.nlm.nih.gov/30917119

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FFAR4 Is Involved in Regulation of Neurotensin Release From Neuroendocrine Cells and Male C57BL/6 Mice

Autor: Xian Li, Jun Song, Jing Li, B. Mark Evers, Heidi L. Weiss, Todd Weiss, Tianyan Gao, Heather F. Sinner, Stephanie B. Rock, Courtney M. Townsend

Publikováno v: Endocrinology. 159(8)

Neurotensin (NT), a 13 amino-acid peptide, is predominantly released from enteroendocrine cells of the small bowel in response to fat ingestion. Free fatty acid receptors (FFARs) FFAR1 and FFAR4 regulate secretion of gut hormones and insulin. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7e9c5e4b86129406ba775379adac18
https://pubmed.ncbi.nlm.nih.gov/29796668

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