Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stephanie A. Fernandes"'
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
The mechanistic Target of Rapamycin (mTOR) is a growth-related kinase that, in the context of the mTOR complex 1 (mTORC1), touches upon most fundamental cellular processes. Consequently, its activity is a critical determinant for cellular and organis
Externí odkaz:
https://doaj.org/article/41af742912324a9394120c3e9e8d7f35
Autor:
Stephanie A. Fernandes, Camila F. Almeida, Lucas S. Souza, Monize Lazar, Paula Onofre-Oliveira, Guilherme L. Yamamoto, Letícia Nogueira, Letícia Y. Tasaki, Rafaela R. Cardoso, Rita C. M. Pavanello, Helga C. A. Silva, Merari F. R. Ferrari, Anne Bigot, Vincent Mouly, Mariz Vainzof, Annemieke Aartsma-Rus, James Dowling, Maaike van Putten
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 2 (2020)
X-linked myopathy with excessive autophagy (XMEA) is a genetic disease associated with weakness of the proximal muscles. It is caused by mutations in the VMA21 gene, coding for a chaperone that functions in the vacuolar ATPase (v-ATPase) assembly. Mu
Externí odkaz:
https://doaj.org/article/b0cb6d4e3d1a46c39a87d324c172427c
Autor:
Camila F. Almeida, Stephanie A. Fernandes, Antonio F. Ribeiro Junior, Oswaldo Keith Okamoto, Mariz Vainzof
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Adult skeletal muscle is a postmitotic tissue with an enormous capacity to regenerate upon injury. This is accomplished by resident stem cells, named satellite cells, which were identified more than 50 years ago. Since their discovery, many researche
Externí odkaz:
https://doaj.org/article/f43c0589045943158d046a0f0f065af8
Autor:
Stephanie A. Fernandes, Andrew G. L. Douglas, Miguel A. Varela, Matthew J. A. Wood, Yoshitsugu Aoki
Publikováno v:
Journal of Nucleic Acids, Vol 2013 (2013)
Amyotrophic lateral sclerosis (ALS) is a progressive and lethal disease of motor neuron degeneration, leading to paralysis of voluntary muscles and death by respiratory failure within five years of onset. Frontotemporal dementia (FTD) is characterise
Externí odkaz:
https://doaj.org/article/7fcb91be1c61498a81e76869cb59b180
Autor:
Camila Ferreira Bomtempo, Stephanie Mara Fernandes Ferrari, Maria Aparecida de Faria Grossi, Sandra Lyon
Publikováno v:
Hansenologia Internationalis, Vol 48 (2023)
Este estudo tem por objetivo avaliar a evolução do grau de incapacidade física e do escore olhos, mãos e pés, do diagnóstico à alta medicamentosa, segundo as variáveis sociodemográficas e clínicas, em pacientes diagnosticados com hansenías
Externí odkaz:
https://doaj.org/article/87702f36ebf442ca968dcde5ead002e5
Autor:
Ricardo Fonseca, Mário De Lemos Alves Neto, Mariana Sidonio Athayde Fonseca Neves, Stephanie Bentolila Fernandes, Vívian Helena Freitas de Almeida, Paula Gabriela Faciola Pessôa de Oliveira, Carlos Eduardo Vieira da Silva Gomes, Tatiany Oliveira de Alencar Menezes, Silvio Augusto Fernandes de Menezes
Publikováno v:
Brazilian Journal of Implantology and Health Sciences. 5:18-28
Introdução: O canino superior é um dente primordial para estética e função oclusal. Estes apresentam depois dos terceiros molares, a maior ocorrência de impactação dentária, principalmente na região palatina. Objetivo: O presente manuscrit
Autor:
Leonardo Santos Bordoni, Stephanie Mara Fernandes Pádua, Juliana Aguiar Cavalcante Diniz, Polyanna Helena Coelho Bordoni, Tatiana Borges Quadros, Camila Ferreira Bomtempo
Publikováno v:
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, Vol 10, Iss 3 (2021)
A antropologia forense lida com perícias criminais de ossadas, cadáveres carbonizados e corpos em avançado estado putrefativo, sendo crucial nesta análise a definição do perfil biológico (PB) com as estimativas do sexo, idade, estatura e ances
Autor:
Wenming Huang, Chun Kew, Stephanie A. Fernandes, Anna Loerhke, Lynn Han, Constantinos Demetriades, Adam Antebi
Changes in splicing fidelity are associated with loss of homeostasis and ageing1–3, yet only a handful of splicing factors have been shown to be causally required to promote longevity 1–3, and the underlying mechanisms and downstream targets in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d892491f1adda540a0f3ad95c20dae2d
https://doi.org/10.1101/2022.03.07.483153
https://doi.org/10.1101/2022.03.07.483153
Autor:
null Stephanie Lorrane Fernandes Celin, null Karina Lima das Chagas, null Geovanna Maciel Luduvichack, null Gabryella da Silva Queiroz
Publikováno v:
Pesquisas e Inovações em Ciências da Saúde e Biológicas: Produções Científicas Multidisciplinares no Século XXI, Volume 3 ISBN: 9786585047180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4e4079a925d2b40908eb81fe6383a1
https://doi.org/10.55232/1084001.32
https://doi.org/10.55232/1084001.32
Autor:
Raffaele Nicastro, Laura Brohée, Josephine Alba, Julian Nüchel, Gianluca Figlia, Stefanie Kipschull, Peter Gollwitzer, Jesus Romero-Pozuelo, Stephanie A. Fernandes, Andreas Lamprakis, Stefano Vanni, Aurelio A. Teleman, Claudio De Virgilio, Constantinos Demetriades
Publikováno v:
bioRxiv
Cell growth is regulated primarily by the mammalian/mechanistic Target of Rapamycin Complex 1 (mTORC1) that functions both as a nutrient sensor and a master controller of virtually all biosynthetic pathways 1. This ensures that cells are metabolicall