Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephanie A. Bonney"'
Autor:
Sheridan M Sargent, Stephanie K Bonney, Yuandong Li, Stefan Stamenkovic, Marc M Takeno, Vanessa Coelho-Santos, Andy Y Shih
Publikováno v:
Vascular Biology, Vol 5, Iss 10, Pp 1-12 (2023)
The high metabolic demand of brain tissue is supported by a constant supply of blood flow through dense microvascular networks. Capillaries are the smallest class of vessels in the brain and their lumens vary in diameter between ~2 and 5 μm. This di
Externí odkaz:
https://doaj.org/article/411f3700b2a449b7a7d1f2b79e710777
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
In the brain, perivascular fibroblasts (PVFs) reside within the perivascular spaces (PVSs) of arterioles and large venules, however their physiological and pathophysiological roles remain largely unknown. PVFs express numerous extracellular matrix pr
Externí odkaz:
https://doaj.org/article/d8ce1e5562174c52a4ace37778bf489f
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/27ca2fa303664abb85c9b9cd6264858f
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Pericytes have myriad functions in cerebrovascular regulation but remain understudied in the living brain. To dissect pericyte functions in vivo, prior studies have used genetic approaches to induce global pericyte loss in the rodent brain. However,
Externí odkaz:
https://doaj.org/article/94971f985fb14114979bed7bdd5fd103
Autor:
Stephanie K. Bonney, Vanessa Coelho-Santos, Sheng-Fu Huang, Marc Takeno, Joergen Kornfeld, Annika Keller, Andy Y. Shih
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Electron microscopy is the primary approach to study ultrastructural features of the cerebrovasculature. However, 2D snapshots of a vascular bed capture only a small fraction of its complexity. Recent efforts to synaptically map neuronal circuitry us
Externí odkaz:
https://doaj.org/article/5484be201f2041d88532a243f42c2417
Autor:
Sheridan M. Sargent, Stephanie K. Bonney, Yuandong Li, Stefan Stamenkovic, Marc Takeno, Vanessa Coelho-Santos, Andy Y. Shih
Publikováno v:
bioRxiv
The high metabolic demand of brain tissue is supported by a constant supply of blood through dense microvascular networks. Capillaries are the smallest class of vessels and vary in diameter between ∼2 to 5 μm in the brain. This diameter range play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab51831ef4546c29d40f6540d6c7653
https://europepmc.org/articles/PMC10168366/
https://europepmc.org/articles/PMC10168366/
Autor:
Hannah E. Jones, Vanessa Coelho-Santos, Stephanie K. Bonney, Kelsey A. Abrams, Andy Y. Shih, Julie A. Siegenthaler
Publikováno v:
bioRxiv
Perivascular fibroblasts (PVFs) are a fibroblast-like cell type that reside on large-diameter blood vessels in the adult meninges and central nervous system (CNS). PVFs drive fibrosis following injury but their homeostatic functions are not well deta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e81942234f09db0dbebdbcaf30a2c8b
https://doi.org/10.1101/2023.03.23.533982
https://doi.org/10.1101/2023.03.23.533982
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 42(6)
Perivascular fibroblasts (PVFs) are recognized for their pro-fibrotic role in many central nervous system disorders. Like mural cells, PVFs surround blood vessels and express Pdgfrβ. However, these shared attributes hinder the ability to distinguish
Autor:
Suzanne E Brooks, Stephanie A Bonney, Cindy Lee, Amy Publicover, Ghazala Khan, Evelien L Smits, Dagmar Sigurdardottir, Matthew Arno, Demin Li, Ken I Mills, Karen Pulford, Alison H Banham, Viggo van Tendeloo, Ghulam J Mufti, Hans-Georg Rammensee, Tim J Elliott, Kim H Orchard, Barbara-ann Guinn
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140483 (2015)
Immunotherapy treatments for cancer are becoming increasingly successful, however to further improve our understanding of the T-cell recognition involved in effective responses and to encourage moves towards the development of personalised treatments
Externí odkaz:
https://doaj.org/article/b51049e2ec5048b2b1dd51c43011470d
Autor:
Stephanie K Bonney, Saskia Lippens, Robert G. Underly, Vanessa Coelho-Santos, Andy Y. Shih, Andrée-Anne Berthiaume, Sharon Ornelas, Christopher J. Guérin, Anna Kremer
Publikováno v:
J Cereb Blood Flow Metab
Pericytes and endothelial cells share membranous interdigitations called “peg-and-socket” interactions that facilitate their adhesion and biochemical crosstalk during vascular homeostasis. However, the morphology and distribution of these ultrast