Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Stephanie A. Amici"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple Sclerosis (MS) is a debilitating central nervous system disorder associated with inflammatory T cells. Activation and expansion of inflammatory T cells is thought to be behind MS relapses and influence disease severity. Protein arginine N-me
Externí odkaz:
https://doaj.org/article/5f71508ff53e43b5b18d587c00503c83
Autor:
Lindsay M. Webb, Janiret Narvaez Miranda, Stephanie A. Amici, Shouvonik Sengupta, Gregory Nagy, Mireia Guerau-de-Arellano
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Multiple sclerosis is an autoimmune disease of the central nervous system (CNS) mediated by CD4+ T cells and modeled via experimental autoimmune encephalomyelitis (EAE). Inhibition of PRMT5, the major Type II arginine methyltransferase, suppresses pa
Externí odkaz:
https://doaj.org/article/ee1831e114f8473083756e99a29a3800
Autor:
Hayam A. Hussein, Mohamed Gomaa, Rochelle J. Deibert, Lesley C. Fisher, Stephanie A. Amici, Mireia Guerau-de-Arellano, Michele D. Basso, Ahmed E. Behery
Publikováno v:
Slovenian Veterinary Research, Vol 55, Iss 20-Suppl (2018)
This study was conducted to characterize the effect of miR-155 overexpression on white matter sparing and lesion size following contusion injury of spinal cord in mice. 60 C57BL/6J wild-type and 60 B6.Cg miR-155 knockout mice were used to induce mode
Externí odkaz:
https://doaj.org/article/542c35884a184779bb52e1d271c6bd63
Autor:
Stephanie A. Amici, Nicholas A. Young, Janiret Narvaez-Miranda, Kyle A. Jablonski, Jesus Arcos, Lucia Rosas, Tracey L. Papenfuss, Jordi B. Torrelles, Wael N. Jarjour, Mireia Guerau-de-Arellano
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophages and their monocyte precursors mediate innate immune responses and can promote a spectrum of phenotypes from pro-inflammatory to pro-resolving. Currently, there are few markers that allow for robust dissection of macrophage phenotype. We r
Externí odkaz:
https://doaj.org/article/3564eb057a264ad89d33eb128e9279d4
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Macrophages and microglia play crucial roles during central nervous system development, homeostasis and acute events such as infection or injury. The diverse functions of tissue macrophages and microglia are mirrored by equally diverse phenotypes. A
Externí odkaz:
https://doaj.org/article/16efcca5d68845e3b753ee44b3cdc0e5
Autor:
Jenny Fortun, Jocelyn C. Go, Jie Li, Stephanie A. Amici, William A. Dunn, Jr., Lucia Notterpek
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 1, Pp 153-164 (2006)
Charcot–Marie–Tooth disease type 1A (CMT1A) is commonly associated with duplication of the peripheral myelin protein 22 (PMP22) gene. Mice expressing seven copies of the human PMP22, termed C22, suffer from a demyelinating neuropathy and display
Externí odkaz:
https://doaj.org/article/d9c4dc648aa5459da00611393cb894ed
Autor:
Michael J. Butler, Shouvonik Sengupta, Stephanie M. Muscat, Stephanie A. Amici, Rebecca G. Biltz, Nicholas P. Deems, Piyush Dravid, Sabrina Mackey-Alfonso, Haanya Ijaz, Menaz N. Bettes, Jonathan P. Godbout, Amit Kapoor, Mireia Guerau-de-Arellano, Ruth M. Barrientos
Publikováno v:
Brain, Behavior, and Immunity. 109:235-250
Autor:
Michael J. Butler, Shouvonik Sengupta, Stephanie Muscat, Stephanie A. Amici, Rebecca G. Biltz, Nicholas P. Deems, Piyush Dravid, Sabrina Mackey-Alfonso, Haanya Ijaz, Menaz N. Bettes, Jonathan P. Godbout, Amit Kapoor, Mireia Guerau-de-Arellano, Ruth M. Barrientos
Publikováno v:
Brain, Behavior, and Immunity.
Autor:
Mayyan Mubarak, Steven Toro, Alexey Dimov, Calvin Park, Mireia Guerau-de-Arellano, Thanh D. Nguyen, Weiyuan Huang, Ulrike W. Kaunzner, Shun Zhang, Maya Levine-Ritterman, Yi Wang, Susan A. Gauthier, David Pitt, Stephanie A. Amici, Kelly M. Gillen, Gerald Ponath
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 877-886 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 877-886 (2021)
Background Inflammation in chronic active lesions occurs behind a closed blood–brain barrier and cannot be detected with MRI. Activated microglia are highly enriched for iron and can be visualized with quantitative susceptibility mapping (QSM), an
Autor:
Stephanie A. Amici, Brandon W Lewis, Joshua A. Englert, Aiman Khan, Mireia Guerau-de-Arellano, Kymberly M Gowdy, Rodney D. Britt, Emily M. Shalosky, Joshua Walum, Michell H Grayson, Hye-Young H. Kim, Ned A. Porter
Publikováno v:
J Immunol
Severe asthma is characterized by steroid insensitivity and poor symptom control and is responsible for most asthma-related hospital costs. Therapeutic options remain limited, in part due to limited understanding of mechanisms driving severe asthma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a9bf862b714439e4fc4d8201fda0b4
https://europepmc.org/articles/PMC9055570/
https://europepmc.org/articles/PMC9055570/