Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Stephanie A Mullane"'
Autor:
Joaquim Bellmunt, Lillian Werner, Jeffrey J Leow, Stephanie A Mullane, André P Fay, Markus Riester, Paul Van Hummelen, Mary-Ellen Taplin, Toni K Choueiri, Eliezer Van Allen, Jonathan Rosenberg
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0124711 (2015)
An integrative analysis was conducted to identify genomic alterations at a pathway level that could predict overall survival (OS) in patients with advanced urothelial carcinoma (UC) treated with platinum-based chemotherapy.DNA and RNA were extracted
Externí odkaz:
https://doaj.org/article/1fd80159b5854ca09a8f19092b7bfff3
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Table 1. Overall cohort characteristics of AAPC whole exome sequencing cohort (n=102) Supplemental Table 2. Clinical and pathological characteristics of AAPC WES discovery cohort (n=102) Supplemental Table 3. Comparison of numbers of tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7d2d64b183edb401be6c8eb683afbd
https://doi.org/10.1158/2159-8290.22531900
https://doi.org/10.1158/2159-8290.22531900
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e6a44282c5e8986299f440da59e71c
https://doi.org/10.1158/2159-8290.22531903
https://doi.org/10.1158/2159-8290.22531903
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e234b8b353d921fe1e1e2d445fb53b2
https://doi.org/10.1158/2159-8290.22531909
https://doi.org/10.1158/2159-8290.22531909
Autor:
Jonathan E. Rosenberg, Gopakumar Iyer, Joaquim Bellmunt, Dean F. Bajorin, Michael F. Berger, David B. Solit, Maria E. Arcila, Bernard H. Bochner, David M. Hyman, Irina Ostrovnaya, Nitin Roper, Eugene K. Cha, Stephanie A. Mullane, Nancy Bouvier, Mariel E. Boyd, Hikmat Al-Ahmadie, Emmet Jordan, Emily C. Zabor, Richard M. Bambury, Min Yuen Teo
Purpose: Platinum-based chemotherapy remains the standard treatment for advanced urothelial carcinoma by inducing DNA damage. We hypothesize that somatic alterations in DNA damage response and repair (DDR) genes are associated with improved sensitivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e85da96b1505a80f8a37cd22ecd103
https://doi.org/10.1158/1078-0432.c.6526446
https://doi.org/10.1158/1078-0432.c.6526446
Autor:
Jonathan E. Rosenberg, Gopakumar Iyer, Joaquim Bellmunt, Dean F. Bajorin, Michael F. Berger, David B. Solit, Maria E. Arcila, Bernard H. Bochner, David M. Hyman, Irina Ostrovnaya, Nitin Roper, Eugene K. Cha, Stephanie A. Mullane, Nancy Bouvier, Mariel E. Boyd, Hikmat Al-Ahmadie, Emmet Jordan, Emily C. Zabor, Richard M. Bambury, Min Yuen Teo
Supplemental Figure 1: The association between deleterious DDR (DNA damage response and repair) alteration status as determined by in silico analysis and (A) Progression-free survival and (B) overall survival, and the association between deleterious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc857c9f76da177c9cb9aebbcf0c823
https://doi.org/10.1158/1078-0432.22466832.v1
https://doi.org/10.1158/1078-0432.22466832.v1
Autor:
Daniele Raggi, Christina Louise Derleth, Andrea Necchi, Joe Simpson, Jae-Lyun Lee, Jonathan E. Rosenberg, Guru Sonpavde, Dean F. Bajorin, Shih-Wen Lin, Ashley Marie Regazzi, Stephanie A. Mullane, Soon Il Lee, Joaquim Bellmunt, Gregory R. Pond, Toni K. Choueiri
Publikováno v:
Clinical Genitourinary Cancer. 16:e961-e967
Introduction Optimal end points in phase 2 trials evaluating salvage therapy for metastatic urothelial carcinoma are necessary to identify promising drugs, particularly immunotherapeutics, where response and progression-free survival may be unreliabl
Autor:
David M. Hyman, Nancy Bouvier, Emmet Jordan, Irina Ostrovnaya, Mariel Elena Boyd, Eugene K. Cha, Bernard H. Bochner, David B. Solit, Michael F. Berger, Min Yuen Teo, Nitin Roper, Dean F. Bajorin, Joaquim Bellmunt, Stephanie A. Mullane, Richard Martin Bambury, Gopakumar Iyer, Emily C. Zabor, Maria E. Arcila, Hikmat Al-Ahmadie, Jonathan E. Rosenberg
Publikováno v:
Clinical Cancer Research. 23:3610-3618
Purpose: Platinum-based chemotherapy remains the standard treatment for advanced urothelial carcinoma by inducing DNA damage. We hypothesize that somatic alterations in DNA damage response and repair (DDR) genes are associated with improved sensitivi
Autor:
Joaquim Bellmunt, Stephanie A. Mullane
Publikováno v:
Current Opinion in Urology. 26:556-563
Immunotherapy in urological cancer has made substantial progress during the last 20 years, but recent advances in immunotherapy have completely transformed the present treatment landscape. In this review, we summarize major clinical achievements of i
Autor:
Jaegil Kim, Anna Orsola, Stephanie A. Mullane, Lillian Werner, David Y. Takeda, William C. Hahn, André P. Fay, Joaquim Bellmunt, Chensheng Willa Zhou, Guru Sonpavde, Michaela Bowden, Mary-Ellen Taplin, Toni K. Choueiri
Publikováno v:
British Journal of Cancer
Repositório Institucional PUCRS
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
Repositório Institucional PUCRS
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
Background: Tumour expression of selected microRNAs (miRs) correlates with cisplatin efficacy in multiple cancers. We investigated the role of selected miRs in patients receiving cisplatin-based therapy for advanced urothelial carcinoma (UC). Methods