Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Stephanie A, Harris"'
Autor:
Marco Polo Peralta-Álvarez, Keya Downward, Andrew White, Hugo Redondo Azema, Laura Sibley, Charlotte Sarfas, Alexandra Morrison, Mike Dennis, Delia Diaz-Santana, Stephanie A. Harris, Shuailin Li, Eugenia Puentes, Nacho Aguilo, Carlos Martin, Sally Sharpe, Helen McShane, Rachel Tanner
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract The only currently licensed vaccine against tuberculosis (TB), Bacille Calmette Guérin (BCG), is insufficient to control the epidemic. MTBVAC is a live attenuated strain of Mycobacterium tuberculosis (M.tb) and is one the most advanced TB v
Externí odkaz:
https://doaj.org/article/2d65dc12fc6546f0b6600b34a9dd124b
Autor:
Timothy Fredsgaard-Jones, Stephanie A. Harris, Hazel Morrison, Alberta Ateere, Beatrice Nassanga, Raquel Lopez Ramon, Celia Mitton, Eve Fletcher, Jonathan Decker, Hannah Preston-Jones, Susan Jackson, Andrew Mawer, Iman Satti, Michael Barer, Timothy Hinks, Henry Bettinson, Helen McShane
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTuberculosis (TB) is the leading cause of death worldwide from a single infectious agent. Bacillus Calmette-Guérin (BCG), the only licensed vaccine, provides limited protection. Controlled human infection models (CHIMs) are useful in acc
Externí odkaz:
https://doaj.org/article/47d09c9689534c6a8e97e1679f846eaf
Publikováno v:
International Journal of Qualitative Methods, Vol 23 (2024)
Asynchronous email interviewing has been increasingly utilized as an electronic method of data collection in qualitative research, because it eliminates the need for costly travel and transcription and allows more time for participants to react with
Externí odkaz:
https://doaj.org/article/3bb008c0bfbf41428072fb26056f6714
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionMoral injury, predominantly studied in military populations, has garnered increased attention in the healthcare setting, in large part due to the psychological and emotional consequences of the COVID-19 pandemic. The measurement of moral
Externí odkaz:
https://doaj.org/article/fd01f9cf66bc4131b80d803dd647a42b
Autor:
Iman Satti, Rachel E. Wittenberg, Shuailin Li, Stephanie A. Harris, Rachel Tanner, Deniz Cizmeci, Ashley Jacobs, Nicola Williams, Humphrey Mulenga, Helen A. Fletcher, Thomas J. Scriba, Michele Tameris, Mark Hatherill, Helen McShane
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The identification of immune correlates of protection in humans would inform on the design and development of tuberculosis vaccine candidates. In this work, authors examine samples collected from South African infants, to determine whether the correl
Externí odkaz:
https://doaj.org/article/fe708fb5f5134f818664bd801fc66d30
Autor:
Morven Wilkie, Rachel Tanner, Daniel Wright, Raquel Lopez Ramon, Julia Beglov, Michael Riste, Julia L. Marshall, Stephanie A. Harris, Paulo J. G. Bettencourt, Ali Hamidi, Pauline M. van Diemen, Paul Moss, Iman Satti, David Wyllie, Helen McShane
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Bacille Calmette-Guérin (BCG), the only currently licenced tuberculosis vaccine, may exert beneficial non-specific effects (NSE) in reducing infant mortality. We conducted a randomised controlled clinical study in healthy UK adults to evalu
Externí odkaz:
https://doaj.org/article/92ca1e31f3be4c04bef9da9dacee16dd
Autor:
Philip Bertrand, Joël Bêty, Nigel G. Yoccoz, Marie-Josée Fortin, Hallvard Strøm, Harald Steen, Jack Kohler, Stephanie M. Harris, Samantha C. Patrick, Olivier Chastel, P. Blévin, Haakon Hop, Geir Moholdt, Joséphine Maton, Sébastien Descamps
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In colonially breeding marine predators, individual movements and colonial segregation are influenced by seascape characteristics. Tidewater glacier fronts are important features of the Arctic seascape and are often described as foraging hot
Externí odkaz:
https://doaj.org/article/2d8f5bd29a11463cacdb9c81a0e14229
Autor:
Rachel Tanner, Andrew D. White, Charelle Boot, Claudia C. Sombroek, Matthew K. O’Shea, Daniel Wright, Emily Hoogkamer, Julia Bitencourt, Stephanie A. Harris, Charlotte Sarfas, Rachel Wittenberg, Iman Satti, Helen A. Fletcher, Frank A. W. Verreck, Sally A. Sharpe, Helen McShane
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract We present a non-human primate mycobacterial growth inhibition assay (MGIA) using in vitro blood or cell co-culture with the aim of refining and expediting early tuberculosis vaccine testing. We have taken steps to optimise the assay using c
Externí odkaz:
https://doaj.org/article/68af0e0e83b24984a10595f180e34dba
Autor:
Julia Bitencourt, Marco Polo Peralta-Álvarez, Morven Wilkie, Ashley Jacobs, Daniel Wright, Salem Salman Almujri, Shuailin Li, Stephanie A. Harris, Steven G. Smith, Sean C. Elias, Andrew D. White, Iman Satti, Sally S. Sharpe, Matthew K. O’Shea, Helen McShane, Rachel Tanner
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore cr
Externí odkaz:
https://doaj.org/article/048b6deb508042c9b23e2a2b29903bc3
Autor:
Rachel Tanner, Emily Hoogkamer, Julia Bitencourt, Andrew White, Charelle Boot, Claudia C. Sombroek, Stephanie A. Harris, Matthew K. O'Shea, Daniel Wright, Rachel Wittenberg, Charlotte Sarfas, Iman Satti, Frank A.W. Verreck, Sally A. Sharpe, Helen A. Fletcher, Helen McShane
Publikováno v:
F1000Research, Vol 10 (2021)
The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulen
Externí odkaz:
https://doaj.org/article/f4d160f312314877839761de896f12a2