Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Stephanie A, Bueler"'
Autor:
Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A. Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C. Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, Katherine Prieto, Stephanie A. Bueler, Sawsan Youssef, Sindy Liao-Chan, Jacob Glanville, Natasha Christie-Holmes, Samira Mubareka, Scott D. Gray-Owen, John L. Rubinstein, Bebhinn Treanor, Jean-Philippe Julien
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, the authors combine three different antibody specificities and an Fc domain on a single multivalent molecule, resulting in high neutralization activity despite viral sequence variability.
Externí odkaz:
https://doaj.org/article/21239c53aca444dbbc85f54151271ca5
Autor:
David J Yanofsky, Justin M Di Trani, Sylwia Król, Rana Abdelaziz, Stephanie A Bueler, Peter Imming, Peter Brzezinski, John L Rubinstein
Publikováno v:
eLife, Vol 10 (2021)
The imidazopyridine telacebec, also known as Q203, is one of only a few new classes of compounds in more than 50 years with demonstrated antituberculosis activity in humans. Telacebec inhibits the mycobacterial respiratory supercomplex composed of co
Externí odkaz:
https://doaj.org/article/1d6aa07f32734bd39aa34dc44cea219b
Autor:
Rana Abdelaziz, Justin M Di Trani, Henok Sahile, Lea Mann, Adrian Richter, Zhongle Liu, Stephanie A. Bueler, Leah E. Cowen, John L. Rubinstein, Peter Imming
Publikováno v:
ACS Omega.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5c13821879697fa7bd3ac939a389bf1
https://doi.org/10.1021/acsomega.3c02259
https://doi.org/10.1021/acsomega.3c02259
Autor:
Thamiya Vasanthakumar, Kristine A. Keon, Stephanie A. Bueler, Michael C. Jaskolka, John L. Rubinstein
Publikováno v:
Nature Structural & Molecular Biology. 29:430-439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94504592dae0600f2dff872f68fa80c
https://doi.org/10.1038/s41594-022-00757-z
https://doi.org/10.1038/s41594-022-00757-z
Autor:
Yingke Liang, Alicia Plourde, Stephanie A. Bueler, Jun Liu, Peter Brzezinski, Siavash Vahidi, John L. Rubinstein
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Oxidative phosphorylation, the combined activity of the electron transport chain (ETC) and adenosine triphosphate synthase, has emerged as a valuable target for the treatment of infection by Mycobacterium tuberculosis and other mycobacteria. The myco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d4ec8bbf3bffc0af30f5804a42cf84
https://doi.org/10.1073/pnas.2214949120
https://doi.org/10.1073/pnas.2214949120
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Vacuolar-type adenosine triphosphatases (V-ATPases) are rotary proton pumps that acidify specific intracellular compartments in almost all eukaryotic cells. These multi-subunit enzymes consist of a soluble catalytic V 1 region and a membrane-embedded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80f175633d5ab03be4048de19c288f61
https://doi.org/10.1073/pnas.2217181120
https://doi.org/10.1073/pnas.2217181120
Vacuolar-type ATPases (V-ATPases) are rotary proton pumps that acidify specific intracellular compartments in almost all eukaryotic cells. These multi-subunit enzymes consist of a soluble catalytic V1region and a membrane-embedded proton-translocatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa2035d4aa11498fdf3201d5742688ca
https://doi.org/10.1101/2022.10.19.512923
https://doi.org/10.1101/2022.10.19.512923
Autor:
Jianhua Zhao, Ksenia Beyrakhova, Yao Liu, Claudia P Alvarez, Stephanie A Bueler, Li Xu, Caishuang Xu, Michal T Boniecki, Voula Kanelis, Zhao-Qing Luo, Miroslaw Cygler, John L Rubinstein
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006394 (2017)
Intracellular pathogenic bacteria evade the immune response by replicating within host cells. Legionella pneumophila, the causative agent of Legionnaires' Disease, makes use of numerous effector proteins to construct a niche supportive of its replica
Externí odkaz:
https://doaj.org/article/25983daec897429b9ce82b455086e88c
Autor:
Yazan M. Abbas, David Dai, Stephanie A. Bueler, Mohammad T. Mazhab-Jafari, Jean-Philippe Julien, S. M. Naimul Hasan, John L. Rubinstein, Geoffrey Woollard
Publikováno v:
Biochemistry. 60:1808-1821
Tuberous sclerosis protein complex (pTSC) nucleates a proteinaceous signaling hub that integrates information about the internal and external energy status of the cell in the regulation of growth and energy consumption. Biochemical and cryo-electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d2a853e3b68e4c2816daaf7667f6bf
https://doi.org/10.1021/acs.biochem.1c00269
https://doi.org/10.1021/acs.biochem.1c00269
Publikováno v:
Nature. 589:143-147
Tuberculosis—the world’s leading cause of death by infectious disease—is increasingly resistant to current first-line antibiotics1. The bacterium Mycobacterium tuberculosis (which causes tuberculosis) can survive low-energy conditions, allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45954d73c1b2e7409cb16c34592dfb98
https://doi.org/10.1038/s41586-020-3004-3
https://doi.org/10.1038/s41586-020-3004-3