Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Stephanie, Trittel"'
Autor:
Lisa Paschold, Cornelia Gottschick, Susan Langer, Bianca Klee, Sophie Diexer, Ivona Aksentijevich, Christoph Schultheiß, Oliver Purschke, Peggy Riese, Stephanie Trittel, Roland Haase, Frank Dressler, Wolfgang Eberl, Johannes Hübner, Till Strowig, Carlos A. Guzman, Rafael Mikolajczyk, Mascha Binder
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract We set out to gain insight into peripheral blood B and T cell repertoires from 120 infants of the LoewenKIDS birth cohort to investigate potential determinants of early life respiratory infections. Low antigen-dependent somatic hypermutation
Externí odkaz:
https://doaj.org/article/9c7fc834ee74407e8789eb9a8157038e
Autor:
Peggy Riese, Stephanie Trittel, Manas K. Akmatov, Marcus May, Jana Prokein, Thomas Illig, Christoph Schindler, Birgit Sawitzki, Yassin Elfaki, Stefan Floess, Jochen Huehn, Adrian J. Błażejewski, Till Strowig, Esteban A. Hernandez-Vargas, Robert Geffers, Bowen Zhang, Yang Li, Frank Pessler, Carlos A. Guzmán
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Seasonal influenza vaccination is an important strategy to prevent serious disease in the elderly, but individual responsiveness to vaccination widely vary. Here authors establish, with an array of state-of-the art methods, the major immunological pa
Externí odkaz:
https://doaj.org/article/9417193549c440fd81f568927dc6de4e
Autor:
Arnika K. Wagner, Nadir Kadri, Chris Tibbitt, Koen van de Ven, Sunitha Bagawath-Singh, Denys Oliinyk, Eric LeGresley, Nicole Campbell, Stephanie Trittel, Peggy Riese, Ulf Ribacke, Tatyana Sandalova, Adnane Achour, Klas Kärre, Benedict J. Chambers
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105137- (2022)
Summary: Although PD-1 was shown to be a hallmark of T cells exhaustion, controversial studies have been reported on the role of PD-1 on NK cells. Here, we found by flow cytometry and single cell RNA sequencing analysis that PD-1 can be expressed on
Externí odkaz:
https://doaj.org/article/99441dde0a53467fba669a0d4271061b
Autor:
Manas K. Akmatov, Peggy Riese, Stephanie Trittel, Marcus May, Jana Prokein, Thomas Illig, Christoph Schindler, Carlos A. Guzmán, Frank Pessler
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The immune response to seasonal influenza vaccines decreases with advancing age. Therefore, an adjuvanted inactivated trivalent influenza vaccine (Fluad®) exists for elderly individuals. Fluad® is more immunogenic and efficaciou
Externí odkaz:
https://doaj.org/article/0805c4c43a8b485c941beb48a82a02dc
Autor:
Martha A. L. Böning, Stephanie Trittel, Peggy Riese, Marco van Ham, Maxi Heyner, Martin Voss, Gerald P. Parzmair, Frank Klawonn, Andreas Jeron, Carlos A. Guzman, Lothar Jänsch, Burkhart Schraven, Annegret Reinhold, Dunja Bruder
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional scaffold and is involved in the formation of immune signaling complexes. To date only limited and moreover conflicting data exist regarding the role of ADAP i
Externí odkaz:
https://doaj.org/article/ce4e454661cc46a7be438dd5540edb06
Autor:
Susan Langer, Johannes Horn, Cornelia Gottschick, Bianca Klee, Oliver Purschke, Mahrrouz Caputo, Evelyn Dorendorf, Kristin Maria Meyer-Schlinkmann, Heike Raupach-Rosin, André Karch, Nicole Rübsamen, Mustafa Aydogdu, Matthias Buhles, Frank Dressler, Wolfgang Eberl, Franz Edler von Koch, Torsten Frambach, Heiko Franz, Florian Guthmann, Carlos A. Guzman, Roland Haase, Gesine Hansen, Valerie Heselich, Johannes Hübner, Hans Georg Koch, Carsten Oberhoff, Peggy Riese, Ralf Schild, Sven Seeger, Michael Tchirikov, Stephanie Trittel, Constantin von Kaisenberg, Rafael Mikolajczyk
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 111 (2022)
Acute respiratory infections (ARIs) are the most common childhood illnesses worldwide whereby the reported frequency varies widely, often depending on type of assessment. Symptom diaries are a powerful tool to counteract possible under-reporting, par
Externí odkaz:
https://doaj.org/article/4c65f7ec03e64837857f7f43cbc3fe99
Autor:
Darío Lirussi, Thomas Ebensen, Kai Schulze, Stephanie Trittel, Veronica Duran, Ines Liebich, Ulrich Kalinke, Carlos A. Guzmán
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 100-111 (2017)
Cyclic di-nucleotides (CDN) are potent stimulators of innate and adaptive immune responses. Cyclic di-AMP (CDA) is a promising adjuvant that generates humoral and cellular immunity. The strong STING-dependent stimulation of type I IFN represents a ke
Externí odkaz:
https://doaj.org/article/cb74b8fdf97b4c9cb8cfd08666b1d745
Autor:
Manas K. Akmatov, Peggy Riese, Marcus May, Leonhard Jentsch, Malik W. Ahmed, Damaris Werner, Anja Rösel, Megan Tyler, Kevin Pessler, Jana Prokein, Inga Bernemann, Norman Klopp, Blair Prochnow, Stephanie Trittel, Aravind Tallam, Thomas Illig, Christoph Schindler, Carlos A. Guzmán, Frank Pessler
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 7, Pp 1630-1639 (2017)
Elderly individuals have the highest burden of disease from influenza infection but also the lowest immune response to influenza vaccination. A better understanding of the host response to influenza vaccination in the elderly is therefore urgently ne
Externí odkaz:
https://doaj.org/article/2f7e0859e8cd42408bf1441a2939e166
Autor:
Stephanie Trittel, Neha Vashist, Thomas Ebensen, Benedict J. Chambers, Carlos A. Guzmán, Peggy Riese
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Non-NK group 1 innate lymphoid cells (ILC1s), mainly investigated in the mucosal areas of the intestine, are well-known to contribute to anti-parasitic and anti-bacterial immune responses. Recently, our group revealed that lung ILC1s become activated
Externí odkaz:
https://doaj.org/article/6b86be7884f144cfa78f56c0d72b4902
Autor:
Peggy Riese, Stephanie Trittel, Rishi D. Pathirana, Frank Klawonn, Rebecca J. Cox, Carlos A. Guzmán
Publikováno v:
Vaccines, Vol 8, Iss 2, p 281 (2020)
Influenza vaccination often results in a large percentage of low responders, especially in high-risk groups. As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. However, their implication with re
Externí odkaz:
https://doaj.org/article/de5c486ef40645348b81653d500ce274