Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephanie, Shiffka"'
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170960 (2017)
Δ4-3-oxosteroid 5β-reductase is member D1 of the aldo-keto reductase family 1 (AKR1D1), which catalyzes 5β-reduction of molecules with a 3-oxo-4-ene structure. Bile acid intermediates and most of the steroid hormones carry the 3-oxo-4-ene structur
Externí odkaz:
https://doaj.org/article/a18a83b90f8446dea9fae35172921522
Autor:
Yuan Chen, Christina Nadolny, Sangmin You, Mwlod Ghareeb, Liangran Guo, Ruitang Deng, Stephanie Shiffka, Ruchi Verma, Leila Valanejad, Fatemeh Akhlaghi
Publikováno v:
Molecular and Cellular Endocrinology. 470:127-141
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ4-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea6e1fba734c01992b162a056acc8bc
https://doi.org/10.1016/j.mce.2017.10.005
https://doi.org/10.1016/j.mce.2017.10.005
Autor:
Xiulong Song, Yuan Chen, Ruchi Verma, Alex Vasilenko, Stephanie Shiffka, Bingfang Yan, Ruitang Deng, Leila Valanejad, Leeza Hargreaves, Christina Nadolny, Sangmin You
Publikováno v:
Molecular Endocrinology. 29:613-626
Among diseases unique to pregnancy, intrahepatic cholestasis of pregnancy is the most prevalent disorder with elevated serum bile acid levels. We have previously shown that estrogen 17β-estradiol (E2) transrepresses bile salt export pump (BSEP) thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd89ca741d442e124fb1da4b4c517331
https://doi.org/10.1210/me.2015-1014
https://doi.org/10.1210/me.2015-1014
Autor:
Leila, Valanejad, Mwlod, Ghareeb, Stephanie, Shiffka, Christina, Nadolny, Yuan, Chen, Liangran, Guo, Ruchi, Verma, Sangmin, You, Fatemeh, Akhlaghi, Ruitang, Deng
Publikováno v:
Molecular and cellular endocrinology. 470
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ(4)-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef279685c951a0c109546331f23f5848
https://pubmed.ncbi.nlm.nih.gov/29024782
https://pubmed.ncbi.nlm.nih.gov/29024782
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170960 (2017)
PLoS ONE, Vol 12, Iss 1, p e0170960 (2017)
Δ4-3-oxosteroid 5β-reductase is member D1 of the aldo-keto reductase family 1 (AKR1D1), which catalyzes 5β-reduction of molecules with a 3-oxo-4-ene structure. Bile acid intermediates and most of the steroid hormones carry the 3-oxo-4-ene structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fbc6f55677d696db3d564af6143385
https://doi.org/10.1371/journal.pone.0170960
https://doi.org/10.1371/journal.pone.0170960