Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stephanie, Puukila"'
Autor:
Marissa Burke, Kelly Wong, Yuli Talyansky, Siddhita D. Mhatre, Carol Mitchell, Cassandra M. Juran, Makaila Olson, Janani Iyer, Stephanie Puukila, Candice G. T. Tahimic, Lane K. Christenson, Moniece Lowe, Linda Rubinstein, Yasaman Shirazi-Fard, Marianne B. Sowa, Joshua S. Alwood, April E. Ronca, Amber M. Paul
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Exposure to cosmic ionizing radiation is an innate risk of the spaceflight environment that can cause DNA damage and altered cellular function. In astronauts, longitudinal monitoring of physiological systems and interactions between these sy
Externí odkaz:
https://doaj.org/article/a49ceff1b5d94721b1f2bc6e8f711071
Autor:
Stephanie Puukila, Olivia Siu, Linda Rubinstein, Candice G. T. Tahimic, Moniece Lowe, Steffy Tabares Ruiz, Ivan Korostenskij, Maya Semel, Janani Iyer, Siddhita D. Mhatre, Yasaman Shirazi-Fard, Joshua S. Alwood, Amber M. Paul, April E. Ronca
Publikováno v:
Life, Vol 13, Iss 5, p 1214 (2023)
Exposure to space galactic cosmic radiation is a principal consideration for deep space missions. While the effects of space irradiation on the nervous system are not fully known, studies in animal models have shown that exposure to ionizing radiatio
Externí odkaz:
https://doaj.org/article/783b8f85f80648558e9d9925d3da7f2f
Autor:
Linda Rubinstein, Frederico Kiffer, Stephanie Puukila, Moniece G. Lowe, Brie Goo, Amalia Luthens, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Candice G. T. Tahimic, Antiño R. Allen
Publikováno v:
Life, Vol 12, Iss 11, p 1838 (2022)
Microgravity (modeled by head-tilt bedrest and hind-limb unloading), experienced during prolonged spaceflight, results in neurological consequences, central nervous system (CNS) dysfunction, and potentially impairment during the performance of critic
Externí odkaz:
https://doaj.org/article/a238ffcabf174beaa0b5206b859522b7
Autor:
Ruth K. Globus, Moniece Lowe, Linda Rubinstein, Joshua S. Alwood, Stephanie Puukila, Amber M. Paul, Siddhita D. Mhatre, Candice Tahimic, Janani Iyer, Sharmila Bhattacharya, Marianne B. Sowa, April E. Ronca
Publikováno v:
Neuroscience & Biobehavioral Reviews. 132:908-935
As human space exploration advances to establish a permanent presence beyond the Low Earth Orbit (LEO) with NASA’s Artemis mission, researchers are striving to understand and address the health challenges of living and working in the spaceflight en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66d4be46e4387516c34da027ea7ba53
https://doi.org/10.1016/j.neubiorev.2021.09.055
https://doi.org/10.1016/j.neubiorev.2021.09.055
Autor:
Shailesh Bihari, Melissa H. Costell, Tara Bouchier, David J. Behm, Mark Burgert, Guosen Ye, Andrew D. Bersten, Stephanie Puukila, Elena Cavallaro, Dennis L. Sprecher, Dani-Louise Dixon
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed3d5ba742ccd6f87d9884f5e6f2777
https://doi.org/10.2139/ssrn.4110953
https://doi.org/10.2139/ssrn.4110953
Autor:
Stephanie Puukila, Mark D. Lawrence, Carmine G. De Pasquale, Andrew D. Bersten, Shailesh Bihari, James McEvoy-May, Ashley Nemec-Bakk, Dani-Louise Dixon
Publikováno v:
Cytokine. 161:156060
Dyspnea, the cardinal manifestation of chronic heart failure (CHF), may reflect both pulmonary oedema and pulmonary remodeling resulting in tissue stiffening. Emerging evidence suggests that predominance of distinct phenotypes of alveolar and recruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d546d855890ed04f3fcc4f895d87b0d4
https://doi.org/10.1016/j.cyto.2022.156060
https://doi.org/10.1016/j.cyto.2022.156060
Autor:
Stephanie Puukila, Sean Bryan, Anna Laakso, Jessica Abdel-Malak, Carli Gurney, Adrian Agostino, Adriane Belló-Klein, Kailash Prasad, Neelam Khaper
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122852 (2015)
Cardiac iron overload is directly associated with cardiac dysfunction and can ultimately lead to heart failure. This study examined the effect of secoisolariciresinol diglucoside (SDG), a component of flaxseed, on iron overload induced cardiac damage
Externí odkaz:
https://doaj.org/article/51b55b1a9f3848daa5ad5ce33d580baa
Acute pulmonary and splenic response in an in vivo model of whole-body low-dose X-radiation exposure
Autor:
Tara Bouchier, Neelam Khaper, James McEvoy, Antony M. Hooker, Douglas R. Boreham, Stacy Muise, Dani-Louise Dixon, Stephanie Puukila
Publikováno v:
International Journal of Radiation Biology. 95:1072-1084
Purpose: Diagnostic radiation is an important part of patient care in the Intensive Care Unit; however, there is little data on the acute effects of exposure to these doses. We investigated...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97fee8c1b673655dda6ad1a9ca95d975
https://doi.org/10.1080/09553002.2019.1625459
https://doi.org/10.1080/09553002.2019.1625459
Autor:
Eveline A I F Queiroz, Stephanie Puukila, Rosangela Eichler, Sandra C Sampaio, Heidi L Forsyth, Simon J Lees, Aneli M Barbosa, Robert F H Dekker, Zuleica B Fortes, Neelam Khaper
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98207 (2014)
Recent studies have demonstrated that the anti-diabetic drug, metformin, can exhibit direct antitumoral effects, or can indirectly decrease tumor proliferation by improving insulin sensitivity. Despite these recent advances, the underlying molecular
Externí odkaz:
https://doaj.org/article/a955e7dd2cae4ccb8c7e6b9b3e8262f4
Autor:
Dani-Louise Dixon, Douglas R. Boreham, Stephanie Puukila, Andrew Johnston, Antony M. Hooker, Peter Haigh
Publikováno v:
Journal of environmental radioactivity.
In order to facilitate direct testing of the biological effects of radon, we designed and constructed a 3.1 m3 radon chamber specifically for radon exposures to small animals. The chamber is designed to operate as a sealed enclosure with a controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb37c981ac3d0ef2ba8fa46d38b99ccc
https://pubmed.ncbi.nlm.nih.gov/32560885
https://pubmed.ncbi.nlm.nih.gov/32560885