Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Stephanie, McArdle"'
Autor:
Adeola Grace Atobatele, Elisa Tonoli, Jayakumar Vadakekolathu, Maria Pia Savoca, Melissa Barr, Yukti Kataria, Marta Rossanese, Izhar Burhan, Stephanie McArdle, Daniela Caccamo, Elisabetta A. M. Verderio
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-13 (2023)
Abstract Androgen independency is associated with poor prostate cancer (PCa) survival. Here we report that silencing of transglutaminase-2 (TG2) expression by CRISPR-Cas9 is associated with upregulation of androgen receptor (AR) transcription in PCa
Externí odkaz:
https://doaj.org/article/13a9f2f11db04ec99babc1d5d0b686a3
Autor:
Aikaterini Nasi, Stephanie McArdle, Gustav Gaudernack, Gabriel Westman, Cornelis Melief, Johan Rockberg, Ramon Arens, Demetrios Kouretas, Jan Sjölin, Sara Mangsbo
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 768-771 (2020)
During the current COVID-19 pandemic, a need for evaluation of already available drugs for treatment of the disease is crucial. Hereby, based on literature review from the current pandemic and previous outbreaks with corona viruses we analyze the imp
Externí odkaz:
https://doaj.org/article/a2b0000d31584847912b4e5ba09418d7
Autor:
Rukaia Almshayakhchi, Divya Nagarajan, Jayakumar Vadakekolathu, Barbara-Ann Guinn, Stephen Reeder, Victoria Brentville, Rachael Metheringham, A. Graham Pockley, Lindy Durrant, Stephanie McArdle
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Many cancers, including myeloid leukaemia express the cancer testis antigen (CTA) DDX43 (HAGE) and/or the oncogene Wilms’ tumour (WT1). Here we demonstrate that HAGE/WT1-ImmunoBody® vaccines derived T-cells can kill ex-vivo human CML cell lines ex
Externí odkaz:
https://doaj.org/article/f437f782c2b54899806b100305362a57
Autor:
Adeola Atobatele, Elisa Tonoli, Jayakumar Vadakekolathu, Maria Pia Savoca, Melissa Barr, Yukti Kataria, Marta Rossanese, Izhar Burhan, Stephanie McArdle, Daniela Caccamo, Elisabetta Verderio
Androgen independency is associated with poor prostate cancer (PCa) survival. Here we report that silencing of transglutaminase-2 (TG2) expression by CRISPR-Cas9 is associated with upregulation of androgen receptor (AR) transcription in prostate canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d59a6a6d8f4e6f36ead4cec5f2549ff
https://doi.org/10.21203/rs.3.rs-2223106/v1
https://doi.org/10.21203/rs.3.rs-2223106/v1
Autor:
Srividya Sundararaman, Alexey Y. Karulin, Tameem Ansari, Nadine BenHamouda, Judith Gottwein, Sreenivas Laxmanan, Steven M. Levine, John T. Loffredo, Stephanie McArdle, Christine Neudoerfl, Diana Roen, Karina Silina, Mackenzie Welch, Paul V. Lehmann
Publikováno v:
Cells, Vol 4, Iss 1, Pp 21-39 (2015)
The primary goal of immune monitoring with ELISPOT is to measure the number of T cells, specific for any antigen, accurately and reproducibly between different laboratories. In ELISPOT assays, antigen-specific T cells secrete cytokines, forming spots
Externí odkaz:
https://doaj.org/article/4b8b577842b84291b39e2adf1401c336
Autor:
Rukaia, Almshayakhchi, Divya, Nagarajan, Jayakumar, Vadakekolathu, Barbara-Ann, Guinn, Stephen, Reeder, Victoria, Brentville, Rachael, Metheringham, A Graham, Pockley, Lindy, Durrant, Stephanie, McArdle
Publikováno v:
Frontiers in Oncology
Many cancers, including myeloid leukaemia express the cancer testis antigen (CTA) DDX43 (HAGE) and/or the oncogene Wilms’ tumour (WT1). Here we demonstrate that HAGE/WT1-ImmunoBody® vaccines derived T-cells can kill ex-vivo human CML cell lines ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8efdefff8a589a3a54ff014326a5c2a
https://pubmed.ncbi.nlm.nih.gov/34262856
https://pubmed.ncbi.nlm.nih.gov/34262856
Autor:
Laura Jayne, Fry, Sergio Querol, Giner, Susana G, Gomez, Melanie, Green, Sally, Anderson, Jackie, Horder, Stephanie, McArdle, Robert, Rees, Jose Alejandro, Madrigal
Publikováno v:
Transfusion. 53(8)
Conditions for maintaining hematopoietic progenitor cells (HPCs) before cryopreservation remain controversial. An understanding of the impact of time and temperature during nonfrozen storage can contribute to the maintenance of the quality of product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c237e59c85c50191b47335507de12f01
https://pubmed.ncbi.nlm.nih.gov/23228098
https://pubmed.ncbi.nlm.nih.gov/23228098
Autor:
Amanda K, Miles, Alistair, Rogers, Thomas, McCulloch, Zsolt, Hodi, Stephanie, McArdle, Michael, Bishop, Robert C, Rees
Publikováno v:
BJU international. 109(5)
• To define the expression pattern of the tumour antigen T21 at the protein level in prostate tissues, prostate cell lines and a panel of normal tissues. • To correlate the expression pattern of T21 in prostate cancer with clinical parameters.•
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d40a61b81500b0db2232c21b03c2e03
https://pubmed.ncbi.nlm.nih.gov/21851547
https://pubmed.ncbi.nlm.nih.gov/21851547
Autor:
Robert C, Rees, Stephanie, McArdle, Shahid, Mian, Geng, Li, Murrium, Ahmad, Richard, Parkinson, Selman A, Ali
Publikováno v:
Current opinion in molecular therapeutics. 4(1)
Disabled infectious single cycle-herpes simplex viruses (DISC-HSV) have been shown to be safe for use in humans and may be considered efficacious as vectors for immunogene therapy in cancer. Preclinical studies show that DISC-HSV is an efficient deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db476775da6fefda9b70469e30ecbc9b
https://pubmed.ncbi.nlm.nih.gov/11883695
https://pubmed.ncbi.nlm.nih.gov/11883695
Autor:
Shahid Mian, Graham Ball, Jo Hornbuckle, Finn Holding, James Carmichael, Ian Ellis, Selman Ali, Geng Li, Stephanie McArdle, Colin Creaser, Robert Rees
Publikováno v:
Proteomics; Sep2003, Vol. 3 Issue 9, p1725-1737, 13p