Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stephanie, Laszig"'
Publikováno v:
HemaSphere, Vol 7, p e68270a4 (2023)
Externí odkaz:
https://doaj.org/article/0d8dfd61499246cc9599feade29229cd
Autor:
Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
BH3 mimetics are promising novel anticancer therapeutics. By selectively inhibiting BCL-2, BCL-xL, or MCL-1 (i.e. ABT-199, A-1331852, S63845) they shift the balance of pro- and anti-apoptotic proteins in favor of apoptosis. As Bromodomain and Extra T
Externí odkaz:
https://doaj.org/article/0403c2302550453288f621f27f8c9d7f
Autor:
Sofia, Gialesaki, Daniela, Bräuer-Hartmann, Hasan, Issa, Raj, Bhayadia, Oriol, Alejo-Valle, Lonneke, Verboon, Anna-Lena, Schmell, Stephanie, Laszig, Eniko Melinda, Regenyi, Konstantin, Schuschel, Maurice, Labuhn, Michelle, Ng, Robert, Winkler, Christian, Ihling, Andrea, Sinz, Markus, Glaß, Stefan, Hüttelmaier, Sören, Matzk, Lena, Schmid, Farina Josepha, Strüwe, Sofie-Katrin, Kadel, Dirk, Reinhardt, Marie-Laure, Yaspo, Dirk, Heckl, Jan-Henning, Klusmann
Publikováno v:
Blood
Gain of chromosome 21 (Hsa21) is among the most frequent aneuploidies in leukemia. However, it remains unclear how partial or complete amplifications of Hsa21 promote leukemogenesis and why children with Down syndrome (i.e. trisomy 21) are particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e032a4734dffe692b74a5e5a2e423759
https://hdl.handle.net/21.11116/0000-000C-6D6E-021.11116/0000-000C-6D70-C
https://hdl.handle.net/21.11116/0000-000C-6D6E-021.11116/0000-000C-6D70-C
Publikováno v:
Cancer letters. 486
Targeting the epigenome of cancer cells with the combination of Bromodomain and Extra Terminal (BET) protein inhibitors and histone deacetylase (HDAC) inhibitors has shown synergistic antitumor effects in several cancer types. In this study, we inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc9a63eda5395b8cad38c733a20b408
https://pubmed.ncbi.nlm.nih.gov/32445837
https://pubmed.ncbi.nlm.nih.gov/32445837