Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Stephanie, LaHaye"'
Autor:
Stephanie LaHaye, James R. Fitch, Kyle J. Voytovich, Adam C. Herman, Benjamin J. Kelly, Grant E. Lammi, Jeremy A. Arbesfeld, Saranga Wijeratne, Samuel J. Franklin, Kathleen M. Schieffer, Natalie Bir, Sean D. McGrath, Anthony R. Miller, Amy Wetzel, Katherine E. Miller, Tracy A. Bedrosian, Kristen Leraas, Elizabeth A. Varga, Kristy Lee, Ajay Gupta, Bhuvana Setty, Daniel R. Boué, Jeffrey R. Leonard, Jonathan L. Finlay, Mohamed S. Abdelbaki, Diana S. Osorio, Selene C. Koo, Daniel C. Koboldt, Alex H. Wagner, Ann-Kathrin Eisfeld, Krzysztof Mrózek, Vincent Magrini, Catherine E. Cottrell, Elaine R. Mardis, Richard K. Wilson, Peter White
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Pediatric cancers typically have a distinct genomic landscape when compared to adult cancers and frequently carry somatic gene fusion events that alter gene expression and drive tumorigenesis. Sensitive and specific detection of g
Externí odkaz:
https://doaj.org/article/1bf38c799d7f4ba18515aabb9dbe24f1
Autor:
Margaret Shatara, Kathleen M. Schieffer, Darren Klawinski, Diana L. Thomas, Christopher R. Pierson, Eric A. Sribnick, Jeremy Jones, Diana P. Rodriguez, Carol Deeg, Elizabeth Hamelberg, Stephanie LaHaye, Katherine E. Miller, James Fitch, Benjamin Kelly, Kristen Leraas, Ruthann Pfau, Peter White, Vincent Magrini, Richard K. Wilson, Elaine R. Mardis, Mohamed S. Abdelbaki, Jonathan L. Finlay, Daniel R. Boué, Catherine E. Cottrell, David R. Ghasemi, Kristian W. Pajtler, Diana S. Osorio
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract Primary spinal cord tumors contribute to ≤ 10% of central nervous system tumors in individuals of pediatric or adolescent age. Among intramedullary tumors, spinal ependymomas make up ~ 30% of this rare tumor population. A twelve-year-old m
Externí odkaz:
https://doaj.org/article/caf4e2efb62e4d51aaa27696a5bedd05
Autor:
Katherine E. Miller, Gregory Wheeler, Stephanie LaHaye, Kathleen M. Schieffer, Sydney Cearlock, Lakshmi Prakruthi Rao Venkata, Alejandro Otero Bravo, Olivia E. Grischow, Benjamin J. Kelly, Peter White, Christopher R. Pierson, Daniel R. Boué, Selene C. Koo, Darren Klawinski, Mark A. Ranalli, Ammar Shaikhouni, Ralph Salloum, Margaret Shatara, Jeffrey R. Leonard, Richard K. Wilson, Catherine E. Cottrell, Elaine R. Mardis, Daniel C. Koboldt
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rhabdoid tumors (RTs) of the brain (atypical teratoid/rhabdoid tumor; AT/RT) and extracranial sites (most often the kidney; RTK) are malignant tumors predominantly occurring in children, frequently those with SMARCB1 germline alterations. Here we pre
Externí odkaz:
https://doaj.org/article/6f21c87851ce462a9ed11e94397b6312
Autor:
Kathleen M. Schieffer, Alexander Z. Feldman, Esko A. Kautto, Sean McGrath, Anthony R. Miller, Maria Elena Hernandez-Gonzalez, Stephanie LaHaye, Katherine E. Miller, Daniel C. Koboldt, Patrick Brennan, Benjamin Kelly, Amy Wetzel, Vibhuti Agarwal, Margaret Shatara, Suzanne Conley, Diana P. Rodriguez, Rolla Abu-Arja, Ala Shaikhkhalil, Matija Snuderl, Brent A. Orr, Jonathan L. Finlay, Diana S. Osorio, Annie I. Drapeau, Jeffrey R. Leonard, Christopher R. Pierson, Peter White, Vincent Magrini, Elaine R. Mardis, Richard K. Wilson, Catherine E. Cottrell, Daniel R. Boué
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Retinoblastoma is a childhood cancer of the retina involving germline or somatic alterations of the RB Transcriptional Corepressor 1 gene, RB1. Rare cases of sellar-suprasellar region retinoblastoma without evidence of ocular or pineal tumor
Externí odkaz:
https://doaj.org/article/85b8e7d1df914feb8bd8c86c7a9bff75
Autor:
Benjamin D. Sunkel, Meng Wang, Stephanie LaHaye, Benjamin J. Kelly, James R. Fitch, Frederic G. Barr, Peter White, Benjamin Z. Stanton
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102867- (2021)
Summary: Recent characterizations of pioneer transcription factors provide insights into their structures and patterns of chromatin recognition associated with their roles in cell fate commitment and transformation. Intersecting with these basic scie
Externí odkaz:
https://doaj.org/article/fefe3a5084d94228bcd526e71cbc8b7d
Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma
Autor:
Mary Frances Wedekind, Katherine E. Miller, Chun-Yu Chen, Pin-Yi Wang, Brian J. Hutzen, Mark A. Currier, Brooke Nartker, Ryan D. Roberts, Louis Boon, Joe Conner, Stephanie LaHaye, Benjamin J. Kelly, David Gordon, Peter White, Elaine R. Mardis, Timothy P. Cripe
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102759- (2021)
Summary: Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent
Externí odkaz:
https://doaj.org/article/42684aaa1ef54305b26e4df761b4bd3f
Autor:
Anthony R, Miller, Saranga, Wijeratne, Sean D, McGrath, Kathleen M, Schieffer, Katherine E, Miller, Kristy, Lee, Mariam, Mathew, Stephanie, LaHaye, James R, Fitch, Benjamin J, Kelly, Peter, White, Elaine R, Mardis, Richard K, Wilson, Catherine E, Cottrell, Vincent, Magrini
Publikováno v:
The Journal of Molecular Diagnostics. 24:1292-1306
Genomic profiling using short-read sequencing has utility in detecting disease-associated variation in both DNA and RNA. However, given the frequent occurrence of structural variation in cancer, molecular profiling using long-read sequencing improves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4491dc650b861f24f390ac883ba4eef
https://doi.org/10.1016/j.jmoldx.2022.09.003
https://doi.org/10.1016/j.jmoldx.2022.09.003
Autor:
Karilyn T. Larkin, Deedra Nicolet, Benjamin J. Kelly, Krzysztof Mrózek, Stephanie LaHaye, Katherine E. Miller, Saranga Wijeratne, Gregory Wheeler, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Isaiah Boateng, Jill Buss, Adrienne Heyrosa, Helee Desai, Andrew J. Carroll, William Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Robert J. Mayer, Richard A. Larson, Richard M. Stone, Electra D. Paskett, John C. Byrd, Elaine R. Mardis, Ann-Kathrin Eisfeld
Publikováno v:
Blood Advances. 6:5570-5581
Survival of patients with acute myeloid leukemia (AML) is inversely associated with age, but the impact of race on outcomes of adolescent and young adult (AYA; range, 18-39 years) patients is unknown. We compared survival of 89 non-Hispanic Black and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f42871e4da56ae8ade725292b2121ab
https://doi.org/10.1182/bloodadvances.2022007544
https://doi.org/10.1182/bloodadvances.2022007544
Autor:
Selene C. Koo, Kathleen M. Schieffer, Kristy Lee, Ajay Gupta, Ruthann B. Pfau, Matthew R. Avenarius, Eileen Stonerock, Stephanie LaHaye, James Fitch, Bhuvana A. Setty, Ryan Roberts, Mark Ranalli, Miriam R. Conces, Fang Bu, Elaine R. Mardis, Catherine E. Cottrell
Publikováno v:
Genes, Chromosomes and Cancer. 62:17-26
Next-generation sequencing (NGS) assays can sensitively detect somatic variation, and increasingly can enable the identification of complex structural rearrangements. A subset of infantile spindle cell sarcomas, particularly congenital mesoblastic ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6a6c5be5dac7082d34f8ca17c19008
https://doi.org/10.1002/gcc.23087
https://doi.org/10.1002/gcc.23087
Autor:
Tracy A. Bedrosian, Katherine E. Miller, Olivia E. Grischow, Kathleen M. Schieffer, Stephanie LaHaye, Hyojung Yoon, Anthony R. Miller, Jason Navarro, Jesse Westfall, Kristen Leraas, Samantha Choi, Rachel Williamson, James Fitch, Benjamin J. Kelly, Peter White, Kristy Lee, Sean McGrath, Catherine E. Cottrell, Vincent Magrini, Jeffrey Leonard, Jonathan Pindrik, Ammar Shaikhouni, Daniel R. Boué, Diana L. Thomas, Christopher R. Pierson, Richard K. Wilson, Adam P. Ostendorf, Elaine R. Mardis, Daniel C. Koboldt
Publikováno v:
Epilepsia. 63:1981-1997
Epilepsy-associated developmental lesions, including malformations of cortical development and low-grade developmental tumors, represent a major cause of drug-resistant seizures requiring surgical intervention in children. Brain-restricted somatic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde007295943450b88f963d23e981af9
https://doi.org/10.1111/epi.17323
https://doi.org/10.1111/epi.17323