Výsledky vyhledávání - "Stephanie, Choi"

Akademický článek

Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions

Autor: Norris Lam, Richard Finney, Shicheng Yang, Stephanie Choi, Xiaolin Wu, Lauren Cutmore, Jorge Andrade, Lei Huang, Christina Amatya, Margaret Cam, James N. Kochenderfer

Publikováno v: Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 132-149 (2023)

To address CD19 loss from lymphoma after anti-CD19 chimeric antigen receptor (CAR) T cell therapy, we designed a bicistronic construct encoding an anti-CD19 CAR and an anti-CD20 CAR. We detected deletions from the expected bicistronic construct seque

Externí odkaz: https://doaj.org/article/8394a243d09d4dd3a0e473ce7dff27d0

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Akademický článek

Hot-Melt Extrusion-Based Dexamethasone–PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation

Autor: Alireza (Allen) Ghaffari, Brock A. Matter, Rachel R. Hartman, David W. A. Bourne, Yan Wang, Stephanie Choi, Uday B. Kompella

Publikováno v: Pharmaceutics, Vol 16, Iss 7, p 895 (2024)

Developing bioequivalent (BE) generic products of complex dosage forms like intravitreal implants (IVIs) of corticosteroids such as dexamethasone prepared using hot-melt extrusion (HME), based on biodegradable poly (lactide-co-glycolide) (PLGA) polym

Externí odkaz: https://doaj.org/article/fe2c7f17f5564f3ea69a8850b4e81a40

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Akademický článek

Author Correction: IFNγ-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/4fd7ed9712ca43fbbfea0936d917d2b4

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Akademický článek

Bilateral exudative retinal detachments after subretinal gene therapy with voretigene neparvovec-rzyl for RPE65 Leber Congenital Amaurosis

Autor: Alcina K. Lidder, Stephanie Choi, Yasha S. Modi, Scott E. Brodie, Janet L. Davis, Ninel Z. Gregori, Byron L. Lam

Publikováno v: American Journal of Ophthalmology Case Reports, Vol 32, Iss , Pp 101879- (2023)

Purpose: To report panuveitis with exudative retinal detachments in a healthy 27-year-old woman with biallelic mutations in the RPE65 gene, who underwent bilateral sequential gene therapy with subretinal administration of voretigene neparvovec-rzyl.

Externí odkaz: https://doaj.org/article/05675087d50e47d2afc8f087a3df93aa

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Akademický článek

Maternal exposure to high‐fat diet during pregnancy and lactation predisposes normal weight offspring mice to develop hepatic inflammation and insulin resistance

Autor: Suchaorn Saengnipanthkul, Hye Lim Noh, Randall H. Friedline, Sujin Suk, Stephanie Choi, Nicholas K. Acosta, Duy A. Tran, Xiaodi Hu, Kunikazu Inashima, Allison M. Kim, Ki Won Lee, Jason K. Kim

Publikováno v: Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)

Abstract Increasing evidence shows a potential link between the perinatal nutrient environment and metabolic outcome in offspring. Here, we investigated the effects of maternal feeding of a high‐fat diet (HFD) during the perinatal period on hepatic

Externí odkaz: https://doaj.org/article/7e3e901846094972a3f3f8a6e838bb42

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