Výsledky vyhledávání - "Stephani Davis"

Data from BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer

Purpose: Current prostate cancer management calls for identifying novel and more effective therapies. Self-renewing tumor-initiating cells (TICs) hold intrinsic therapy resistance and account for tumor relapse and progression. As BMI-1 regulates stem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925153583244741b63d2ce956090ae1f
https://doi.org/10.1158/1078-0432.c.6527079.v1

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Supplementary data from BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer

Supplementary data Figure S1. Functional role(s) of BMI-1 in PCa. Figure S2. BMI-1 expression in subpopulations of DU145 cells. Figure S3. Pharmacological inhibition of BMI-1. Figure S4. Molecular and cellular effects of pharmacological targeting of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffced9ef7f9a1c40d742ab4b16fc4aa
https://doi.org/10.1158/1078-0432.22468857

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Enrichment of human prostate cancer cells with tumor initiating properties in mouse and zebrafish xenografts by differential adhesion

Autor: Nitu, Bansal, Stephani, Davis, Irina, Tereshchenko, Tulin, Budak-Alpdogan, Hua, Zhong, Mark N, Stein, Isaac Yi, Kim, Robert S, Dipaola, Joseph R, Bertino, Hatem E, Sabaawy

Publikováno v: The Prostate. 74(2)

Prostate tumor-initiating cells (TICs) have intrinsic resistance to current therapies. TICs are commonly isolated by cell sorting or dye exclusion, however, isolating TICs from limited primary prostate cancer (PCa) tissues is inherently inefficient.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a52db46c5e148de5d4f94685eb71229
https://pubmed.ncbi.nlm.nih.gov/24154958

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