Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stephane R. B. Heymans"'
Autor:
Jerremy Weerts, Anne G. Raafs, Birgit Sandhoefner, Frank C. T. van der Heide, Sanne G. J. Mourmans, Nicolas Wolff, Robert P. Finger, Peyman Falahat, Maximilian W. M. Wintergerst, Vanessa P. M. van Empel, Stephane R. B. Heymans
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 7, p 1892 (2024)
Background: Systemic microvascular regression and dysfunction are considered important underlying mechanisms in heart failure with preserved ejection fraction (HFpEF), but retinal changes are unknown. Methods: This prospective study aimed to investig
Externí odkaz:
https://doaj.org/article/539bff002a9442779239258c689d8d8c
Autor:
Maurits A. Sikking, Sophie L. V. M. Stroeks, Olivia J. Waring, Michiel T. H. M. Henkens, Niels P. Riksen, Alexander Hoischen, Stephane R. B. Heymans, Job A. J. Verdonschot
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 15 (2023)
ABSTRACT Clonal hematopoiesis of indeterminate potential (CHIP) is a common bone marrow abnormality induced by age‐related DNA mutations, which give rise to proinflammatory immune cells. These immune cells exacerbate atherosclerotic cardiovascular
Externí odkaz:
https://doaj.org/article/23ac293c782343308b91a5c1bca21054
Autor:
Anne G. Raafs, Bouke P. Adriaans, Michiel T. H. M. Henkens, Job A. J. Verdonschot, Myrurgia A. Abdul Hamid, Javier Díez, Christian Knackstedt, Vanessa P. M. van Empel, Hans-Peter Brunner-La Rocca, Arantxa González, Joachim E. Wildberger, Stephane R. B. Heymans, Mark R. Hazebroek
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 17, p 5695 (2023)
Background: Collagen cross-linking is a fundamental process in dilated cardiomyopathy (DCM) and occurs when collagen deposition exceeds degradation, leading to impaired prognosis. This study investigated the associations of collagen-metabolism biomar
Externí odkaz:
https://doaj.org/article/16ee41565c354b0ba48dcad939d50fec
Autor:
Maurits A. Sikking, Sophie L. V. M. Stroeks, Michiel T. H. M. Henkens, Max F. G. H. M. Venner, Xiaofei Li, Stephane R. B. Heymans, Mark R. Hazebroek, Job A. J. Verdonschot
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 12, p 3937 (2023)
Dilated cardiomyopathy (DCM) has a genetic cause in up to 40% of cases, with differences in disease penetrance and clinical presentation, due to different exogeneous triggers and implicated genes. Cardiac inflammation can be the consequence of an exo
Externí odkaz:
https://doaj.org/article/9018c1554107469988f536bb2132b926
Autor:
Sharon Remmelzwaal, Joline W. J. Beulens, Petra J. M. Elders, Coen D. A. Stehouwer, M. Louis Handoko, Yolande Appelman, Vanessa van Empel, Stephane R. B. Heymans, A. Johanne van Ballegooijen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract We investigated the prospective associations of body composition with cardiac structure and function and explored effect modification by sex and whether inflammation was a mediator in these associations. Total body (BF), trunk (TF) and leg f
Externí odkaz:
https://doaj.org/article/ec0cb59f868046b6b112db214b955ed1
Autor:
Jacqueline L. Vos, Anne G. Raafs, Nikki van der Velde, Tjeerd Germans, Paul Stefan Biesbroek, Kit Roes, Alexander Hirsch, Stephane R. B. Heymans, Robin Nijveldt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Background Late gadolinium enhancement and left ventricular (LV) ejection fraction on cardiovascular magnetic resonance (CMR) are prognostic markers, but their predictive value for incident heart failure or life‐threatening arrhythmias in acute myo
Externí odkaz:
https://doaj.org/article/8747c542379d4ae2bfd255948b328cab
Autor:
Job A. J. Verdonschot, João Pedro Ferreira, Pierpaolo Pellicori, Hans-Peter Brunner-La Rocca, Andrew L. Clark, Franco Cosmi, Joe Cuthbert, Nicolas Girerd, Beatrice Mariottoni, Johannes Petutschnigg, Patrick Rossignol, John G. F. Cleland, Faiez Zannad, Stephane R. B. Heymans, HOMAGE “Heart Omics in AGEing” consortium
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Patients with diabetes mellitus (DM) are at increased risk of developing heart failure (HF). The “Heart OMics in AGEing” (HOMAGE) trial suggested that spironolactone had beneficial effect on fibrosis and cardiac remodelling in
Externí odkaz:
https://doaj.org/article/e14de118673048909bafad7206cc7788
Autor:
Michiel T. H. M. Henkens, Helena López Martínez, Jerremy Weerts, Arjan Sammani, Anne G. Raafs, Job A. J. Verdonschot, Rutger R. van de Leur, Maurits A. Sikking, Sophia Stroeks, Vanessa P. M. van Empel, Hans‐Peter Brunner‐La Rocca, Antonius M. W. van Stipdonk, Dimitrios Farmakis, Mark R. Hazebroek, Kevin Vernooy, Antoni Bayés‐de‐Luna, Folkert W. Asselbergs, Antoni Bayés‐Genís, Stephane R. B. Heymans
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 14 (2022)
Background Interatrial block (IAB) has been associated with supraventricular arrhythmias and stroke, and even with sudden cardiac death in the general population. Whether IAB is associated with life‐threatening arrhythmias (LTA) and sudden cardiac
Externí odkaz:
https://doaj.org/article/cb4fdebc7223417d8eb115fbd394b9be
Autor:
Anne G. Raafs, Andrea Boscutti, Michiel T. H. M. Henkens, Wout W. A. van den Broek, Job A. J. Verdonschot, Jerremy Weerts, Davide Stolfo, Vincenzo Nuzzi, Paolo Manca, Mark R. Hazebroek, Christian Knackstedt, Marco Merlo, Stephane R. B. Heymans, Gianfranco Sinagra
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 6 (2022)
Background Speckle tracking echocardiographic global longitudinal strain (GLS) predicts outcome in patients with new onset heart failure. Still, its incremental value on top of left ventricular ejection fraction (LVEF) in patients with nonischemic, n
Externí odkaz:
https://doaj.org/article/41cf2c74ee1c446f935ead66325c9b6a
Autor:
Sharon Remmelzwaal, Adriana J. van Ballegooijen, Linda J. Schoonmade, Elisa Dal Canto, M. Louis Handoko, Michiel T. H. M. Henkens, Vanessa van Empel, Stephane R. B. Heymans, Joline W. J. Beulens
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background An overview of the diagnostic performance of natriuretic peptides (NPs) for the detection of diastolic dysfunction (DD) and heart failure with preserved ejection fraction (HFpEF), in a non-acute setting, is currently lacking. Meth
Externí odkaz:
https://doaj.org/article/bec7f4f7cf1b4ec491b83b6b05691fdb