Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephane R B Heymans"'
Autor:
Sharon Remmelzwaal, Joline W J Beulens, Petra J M Elders, Coen D A Stehouwer, Zhenyu Zhang, M Louis Handoko, Yolande Appelman, Vanessa van Empel, Stephane R B Heymans, Lutgarde Thijs, Jan A Staessen, A Johanne van Ballegooijen
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251148 (2021)
BackgroundThis study aimed to determine the within-person and between-persons associations of low-grade inflammation (LGI) and endothelial dysfunction (ED) with echocardiographic measures related to diastolic dysfunction (DD) in two general populatio
Externí odkaz:
https://doaj.org/article/f16a21d3f1e341fdb23700860bb5fdaf
Autor:
Maurits A. Sikking, Sophie L. V. M. Stroeks, Olivia J. Waring, Michiel T. H. M. Henkens, Niels P. Riksen, Alexander Hoischen, Stephane R. B. Heymans, Job A. J. Verdonschot
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 15 (2023)
ABSTRACT Clonal hematopoiesis of indeterminate potential (CHIP) is a common bone marrow abnormality induced by age‐related DNA mutations, which give rise to proinflammatory immune cells. These immune cells exacerbate atherosclerotic cardiovascular
Externí odkaz:
https://doaj.org/article/23ac293c782343308b91a5c1bca21054
Autor:
Jacqueline L. Vos, Anne G. Raafs, Nikki van der Velde, Tjeerd Germans, Paul Stefan Biesbroek, Kit Roes, Alexander Hirsch, Stephane R. B. Heymans, Robin Nijveldt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Background Late gadolinium enhancement and left ventricular (LV) ejection fraction on cardiovascular magnetic resonance (CMR) are prognostic markers, but their predictive value for incident heart failure or life‐threatening arrhythmias in acute myo
Externí odkaz:
https://doaj.org/article/8747c542379d4ae2bfd255948b328cab
Autor:
Sharon Remmelzwaal, Adriana J. van Ballegooijen, Linda J. Schoonmade, Elisa Dal Canto, M. Louis Handoko, Michiel T. H. M. Henkens, Vanessa van Empel, Stephane R. B. Heymans, Joline W. J. Beulens
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background An overview of the diagnostic performance of natriuretic peptides (NPs) for the detection of diastolic dysfunction (DD) and heart failure with preserved ejection fraction (HFpEF), in a non-acute setting, is currently lacking. Meth
Externí odkaz:
https://doaj.org/article/bec7f4f7cf1b4ec491b83b6b05691fdb
Autor:
Anne G. Raafs, Andrea Boscutti, Michiel T. H. M. Henkens, Wout W. A. van den Broek, Job A. J. Verdonschot, Jerremy Weerts, Davide Stolfo, Vincenzo Nuzzi, Paolo Manca, Mark R. Hazebroek, Christian Knackstedt, Marco Merlo, Stephane R. B. Heymans, Gianfranco Sinagra
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 6 (2022)
Background Speckle tracking echocardiographic global longitudinal strain (GLS) predicts outcome in patients with new onset heart failure. Still, its incremental value on top of left ventricular ejection fraction (LVEF) in patients with nonischemic, n
Externí odkaz:
https://doaj.org/article/41cf2c74ee1c446f935ead66325c9b6a
Autor:
Job A. J. Verdonschot, Emma L. Robinson, Kiely N. James, Mohamed W. Mohamed, Godelieve R. F. Claes, Kari Casas, Els K. Vanhoutte, Mark R. Hazebroek, Gabriel Kringlen, Michele M. Pasierb, Arthur van denWijngaard, Jan F. C. Glatz, Stephane R. B. Heymans, Ingrid P. C. Krapels, Shareef Nahas, Han G. Brunner, Radek Szklarczyk
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract Background A causal genetic mutation is found in 40% of families with dilated cardiomyopathy (DCM), leaving a large percentage of families genetically unsolved. This prevents adequate counseling and clear recommendations in these families. W
Externí odkaz:
https://doaj.org/article/4c768b28545c4e9c80d7adf8d44f46ec
Autor:
Job A. J. Verdonschot, Mark R. Hazebroek, James S. Ware, Sanjay K. Prasad, Stephane R. B. Heymans
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)
Externí odkaz:
https://doaj.org/article/1603290b2efc48deb0fce6fe5dc81fa3
Autor:
Verdonschot, Maurits A. Sikking, Sophie L. V. M. Stroeks, Michiel T. H. M. Henkens, Max F. G. H. M. Venner, Xiaofei Li, Stephane R. B. Heymans, Mark R. Hazebroek, Job A. J.
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 12; Pages: 3937
Dilated cardiomyopathy (DCM) has a genetic cause in up to 40% of cases, with differences in disease penetrance and clinical presentation, due to different exogeneous triggers and implicated genes. Cardiac inflammation can be the consequence of an exo
Autor:
Jacqueline L Vos, Anne G Raafs, Michiel T H M Henkens, Gianni Pedrizzetti, Caroline J van Deursen, Laura Rodwell, Stephane R B Heymans, Robin Nijveldt
Publikováno v:
European Heart Journal - Cardiovascular Imaging.
Aims Left ventricular (LV) blood flow is determined by intraventricular pressure gradients (IVPG). Changes in blood flow initiate remodelling and precede functional decline. Novel cardiac magnetic resonance (CMR) post-processing LV-IVPG analysis migh
Autor:
Sharon, Remmelzwaal, Sabine, van Oort, M Louis, Handoko, Vanessa, van Empel, Stephane R B, Heymans, Joline W J, Beulens
Publikováno v:
Journal of cardiovascular medicine (Hagerstown, Md.). 23(11)
It is hypothesized that inflammation leads to heart failure. Results from observational studies thus far have been inconsistent and it is unclear whether inflammation is causally associated with new-onset heart failure. Mendelian randomization analys