Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Stephane L Bourque"'
Autor:
Dean A Fergusson, Marc T Avey, Carly C Barron, Mathew Bocock, Kristen E Biefer, Sylvain Boet, Stephane L Bourque, Isidora Conic, Kai Chen, Yuan Yi Dong, Grace M Fox, Ronald B George, Neil M Goldenberg, Ferrante S Gragasin, Prathiba Harsha, Patrick J Hong, Tyler E James, Sarah M Larrigan, Jenna L MacNeil, Courtney A Manuel, Sarah Maximos, David Mazer, Rohan Mittal, Ryan McGinn, Long H Nguyen, Abhilasha Patel, Philippe Richebé, Tarit K Saha, Benjamin E Steinberg, Sonja D Sampson, Duncan J Stewart, Summer Syed, Kimberly Vella, Neil L Wesch, Manoj M Lalu, Canadian Perioperative Anesthesia Clinical Trials Group
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215221 (2019)
Poor reporting quality may contribute to irreproducibility of results and failed 'bench-to-bedside' translation. Consequently, guidelines have been developed to improve the complete and transparent reporting of in vivo preclinical studies. To examine
Externí odkaz:
https://doaj.org/article/a41cd83c1ab14abfbdd7bdf3fab9263c
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202871 (2018)
BACKGROUND:Medication overdose is a prevalent issue and despite mixed reports of efficacy, the use of intravenous lipid emulsions, notably Intralipid®, for the management of toxicity from lipid-soluble drugs is becoming increasingly prevalent. Wheth
Externí odkaz:
https://doaj.org/article/596fb689b7404c16b5e65aa562da1f25
Autor:
Yana Kibalnyk, Elia Afanasiev, Ronan M. N. Noble, Adrianne E. S. Watson, Irina Poverennaya, Nicole L. Dittmann, Maria Alexiou, Kara Goodkey, Amanda A. Greenwell, John R. Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L. Bourque, Jo Anne Stratton, Anastassia Voronova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract ANKRD11 (Ankyrin Repeat Domain 11) is a chromatin regulator and a causative gene for KBG syndrome, a rare developmental disorder characterized by multiple organ abnormalities, including cardiac defects. However, the role of ANKRD11 in heart
Externí odkaz:
https://doaj.org/article/ce8c90516c504572ba5ad45d0a89daf1
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61861 (2013)
Intra-uterine growth restriction (IUGR) has been associated with increased predisposition to age-related complications. We tested the hypothesis that rat offspring models of IUGR would exhibit exacerbated, age-related retinal dysfunction.Female Sprag
Externí odkaz:
https://doaj.org/article/76e2f0f00df64fe5bdd670335d84ff9a
Autor:
Neha Sharma, Damian Chwastek, Dhruva J. Dwivedi, Jared Schlechte, Ian-Ling Yu, Braedon McDonald, Jaskirat Arora, Erblin Cani, Mikaela Eng, Doreen Engelberts, Eva Kuhar, Sarah K. Medeiros, Stephane L. Bourque, Gediminas Cepinskas, Sean E. Gill, Forough Jahandideh, Kimberly F. Macala, Sareh Panahi, Cynthia Pape, David Sontag, Janet Sunohara-Neilson, Dean A. Fergusson, Alison E. Fox-Robichaud, Patricia C. Liaw, Manoj M. Lalu, Asher A. Mendelson, for the National Preclinical Sepsis Platform, Sepsis Canada
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Preclinical sepsis models have been criticized for their inability to recapitulate human sepsis and suffer from methodological shortcomings that limit external validity and reproducibility. The National Preclinical Sepsis Platform
Externí odkaz:
https://doaj.org/article/2a7fa924fb5b4658b0da38387de75a6e
Autor:
MengQi Zhang, Dean A. Fergusson, Rahul Sharma, Ciel Khoo, Asher A. Mendelson, Braedon McDonald, Kimberly F. Macala, Neha Sharma, Sean E. Gill, Kirsten M. Fiest, Christian Lehmann, Risa Shorr, Forough Jahandideh, Stephane L. Bourque, Patricia C. Liaw, Alison Fox-Robichaud, Manoj M. Lalu, on behalf of the Canadian Critical Care Translational Biology Group, the Sepsis Canada National Preclinical Sepsis Platform
Publikováno v:
Systematic Reviews, Vol 12, Iss 1, Pp 1-9 (2023)
Abstract Background The importance of investigating sex- and gender-dependent differences has been recently emphasized by major funding agencies. Notably, the influence of biological sex on clinical outcomes in sepsis is unclear, and observational st
Externí odkaz:
https://doaj.org/article/19f1ce8a2d3b487d9eec9135366362f3
Publikováno v:
Food Chemistry: X, Vol 13, Iss , Pp 100222- (2022)
Diabetes mellitus, a group of metabolic disorders characterized by persistent hyperglycemia, affects millions of people worldwide and is on the rise. Dietary proteins, from a wide range of food sources, are rich in bioactive peptides with antidiabeti
Externí odkaz:
https://doaj.org/article/fad71e5326ec427180484baacc207bc7
Autor:
Saad Y. Salim, Nour AlMalki, Kimberly F. Macala, Alyssa Wiedemeyer, Thomas F. Mueller, Thomas A. Churchill, Stephane L. Bourque, Rachel G. Khadaroo
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 483 (2023)
Sepsis remains one of the leading causes of death worldwide. Oncostatin M (OSM), an interleukin (IL)-6 family cytokine, can be found at high levels in septic patients. However, little is known about its role in sepsis. This study aimed to determine i
Externí odkaz:
https://doaj.org/article/9e6ec6197c06438bb0d4a755e66efbd6
Autor:
Sandra T. Davidge, Stephane L. Bourque
Publikováno v:
Clinical Science. 134:3023-3046
The developmental origins of health and disease (DOHaD) is a concept linking pre- and early postnatal exposures to environmental influences with long-term health outcomes and susceptibility to disease. It has provided a new perspective on the etiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d125bacf61c9355fd0b647f966b4f159
https://doi.org/10.1042/cs20191210
https://doi.org/10.1042/cs20191210
Autor:
Kelsea M. Drall, Andrew J. Forgie, Stephane L. Bourque, Benjamin P. Willing, Anita L. Kozyrskyj, Catherine J. Field
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
BMC Medicine
BMC Medicine
Background Early-life malnutrition may have long-lasting effects on microbe-host interactions that affect health and disease susceptibility later in life. Diet quality and quantity in conjunction with toxin and pathogen exposure are key contributors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc69f3adb9230935a18cd8571636257c
http://link.springer.com/article/10.1186/s12916-020-01584-z
http://link.springer.com/article/10.1186/s12916-020-01584-z