Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Stephane Hua"'
Autor:
Xiaoming Sun, Stephane Hua, Ce Gao, Jane E. Blackmer, Zhengyu Ouyang, Kevin Ard, Andrea Ciaranello, Sigal Yawetz, Paul E. Sax, Eric S. Rosenberg, Mathias Lichterfeld, Xu G. Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Zika virus (ZIKV) poses a significant public health threat, but the immune landscape changes following ZIKV infection is still unclear. Here, the authors show, using flow cytometry and transcriptomic data, that ZIKV induces a multitude of immune resp
Externí odkaz:
https://doaj.org/article/22635906b94d4ef385dfa69cc1d812bc
Autor:
Xiaoming Sun, Stephane Hua, Hsiao-Rong Chen, Zhengyu Ouyang, Kevin Einkauf, Samantha Tse, Kevin Ard, Andrea Ciaranello, Sigal Yawetz, Paul Sax, Eric S. Rosenberg, Mathias Lichterfeld, Xu G. Yu
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3471-3482 (2017)
Summary: Although dendritic cells are among the human cell population best equipped for cell-intrinsic antiviral immune defense, they seem highly susceptible to infection with the Zika virus (ZIKV). Using highly purified myeloid dendritic cells isola
Externí odkaz:
https://doaj.org/article/58d6d72cb86f4f28a1a3839ceda3c2f4
Autor:
Nathan W Cummins, Stacey Rizza, Mark R Litzow, Stephane Hua, Guinevere Q Lee, Kevin Einkauf, Tae-Wook Chun, Frank Rhame, Jason V Baker, Michael P Busch, Nicolas Chomont, Patrick G Dean, Rémi Fromentin, Ashley T Haase, Dylan Hampton, Sheila M Keating, Steven M Lada, Tzong-Hae Lee, Sekar Natesampillai, Douglas D Richman, Timothy W Schacker, Stephen Wietgrefe, Xu G Yu, Joseph D Yao, John Zeuli, Mathias Lichterfeld, Andrew D Badley
Publikováno v:
PLoS Medicine, Vol 14, Iss 11, p e1002461 (2017)
BACKGROUND:Notwithstanding 1 documented case of HIV-1 cure following allogeneic stem cell transplantation (allo-SCT), several subsequent cases of allo-SCT in HIV-1 positive individuals have failed to cure HIV-1 infection. The aim of our study was to
Externí odkaz:
https://doaj.org/article/6cb0f7ce4309430794213dddfb5bf122
Autor:
Mary Carrington, Joseph Varriale, Robert F. Siliciano, Joshua M. Chevalier, Jane E. Blackmer, Ma Somsouk, Sarah E. Sweet, Kevin Einkauf, Erik Serrao, Stephane Hua, Bruce D. Walker, Janet M. Siliciano, Kaylee Chang, Mathias Lichterfeld, Michael J. Peluso, Ce Gao, Xiaoming Sun, Jeffrey M. Milush, Matthew Osborn, Tae Wook Chun, Rebecca Hoh, Xu G. Yu, Gregory M. Laird, Lynn N. Bertagnolli, Steven G. Deeks, Chenyang Jiang, Peter D. Burbelo, Ben Rhee, Alan Engelman, Samantha M.Y. Chen, Xiao-Dong Lian
Publikováno v:
Nature. 585:261-267
Sustained, drug-free control of HIV-1 replication is naturally achieved in less than 0.5% of infected individuals (here termed ‘elite controllers’), despite the presence of a replication-competent viral reservoir1. Inducing such an ability to spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0245f5e7116bf3a6fb70b7ea751734df
https://doi.org/10.1038/s41586-020-2651-8
https://doi.org/10.1038/s41586-020-2651-8
Autor:
Mathias Lichterfeld, Kevin Einkauf, Xu G. Yu, Jonathan Z. Li, Fatema Z. Chowdhury, Guinevere Q. Lee, Xiaoming Sun, Stephane Hua, Ce Gao, Xiao-Dong Lian, Tae-Wook Chun, Samantha M.Y. Chen, Eric S. Rosenberg, Radwa Sharaf, Chenyang Jiang
Publikováno v:
Journal of Clinical Investigation. 129:988-998
Chromosomal integration of genome-intact HIV-1 sequences into the host genome creates a reservoir of virally infected cells that persists throughout life, necessitating indefinite antiretroviral suppression therapy. During effective antiviral treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eacdfa577f07bd7919bd171f7b54e97
https://doi.org/10.1172/jci124291
https://doi.org/10.1172/jci124291
Autor:
Christine Bourgeois, Lluis Quintana-Murci, Faivre, Stephane Hua, Kim Zita Martinet, Boniotto M, Lukaszewicz Ac, Didier Payen, Pierre Tissieres, Miatello J
Monocyte HLA-DR is an increasingly recognized markers of sepsis-induced immunodepression, but its regulatory mechanisms remain poorly understood in sepsis. Several evidence for positive selection on the 5’ promoter region of HLA class II transactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b8d97e7b88460fc756c4003b28bb60
https://doi.org/10.1101/2021.02.19.21252097
https://doi.org/10.1101/2021.02.19.21252097
Autor:
Céline Gommet, Roger Le Grand, Catherine Chapon, Mariangela Cavarelli, Nathalie Dereuddre-Bosquet, Naima Hantour, Sabine Tricot, Nicolas Tchitchek, Hakim Hocini, Stephane Hua
Publikováno v:
Communications Biology
Communications Biology, 2021, 4, pp.861. ⟨10.1038/s42003-021-02383-9⟩
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology, Nature Publishing Group, 2021, 4, pp.861. ⟨10.1038/s42003-021-02383-9⟩
Communications Biology, 2021, 4, pp.861. ⟨10.1038/s42003-021-02383-9⟩
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology, Nature Publishing Group, 2021, 4, pp.861. ⟨10.1038/s42003-021-02383-9⟩
Mucosal exposure to infected semen accounts for the majority of HIV-1 transmission events, with rectal intercourse being the route with the highest estimated risk of transmission. Yet, the impact of semen inflammation on colorectal HIV-1 transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34922276c3e2ee93d1ee6c47e556a737
https://hal.sorbonne-universite.fr/hal-03287057
https://hal.sorbonne-universite.fr/hal-03287057
Autor:
Ce Gao, Xiaoming Sun, Andrea L. Ciaranello, Eric S. Rosenberg, Sigal Yawetz, Xu G. Yu, Zhengyu Ouyang, Mathias Lichterfeld, Jane E. Blackmer, Kevin L. Ard, Stephane Hua, Paul E. Sax
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Zika virus (ZIKV) is a mosquito-borne pathogen with increasing public health significance. To characterize immune responses to ZIKV, here we examine transcriptional signatures of CD4 T, CD8 T, B, and NK cells, monocytes, myeloid dendritic cells (mDCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebbcad73bffd0637fc3fc2d19bebb5d
http://europepmc.org/articles/PMC7229207
http://europepmc.org/articles/PMC7229207
Autor:
Hadi Shafiee, Xu G. Yu, Maryam Moazeni, Yudong Li, Xiaoming Sun, Manasa Venkataramani, Anish Vasan, Mohamed Shehata Draz, Stephane Hua, Harini Lakshminarayanan, Ecem Saygili
Publikováno v:
Nanoscale. 10:11841-11849
Zika virus (ZIKV) is a reemerging flavivirus causing an ongoing pandemic and public health emergency worldwide. There are currently no effective vaccines or specific therapy for Zika infection. Rapid, low-cost diagnostics for mass screening and early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ba96e535b89d744f047c9cd0b1e6d5
https://doi.org/10.1039/c8nr01646a
https://doi.org/10.1039/c8nr01646a
Autor:
Sean Harrington, Mathias Lichterfeld, Manuel Leal, Samantha Tse, Ezequiel Ruiz-Mateos, Stephane Hua, Pilar Garcia-Broncano, Xu G. Yu, Miguel Genebat, Giulia Marchetti, Selena Vigano, Jordi Negron, Ouyang Zhengyu, Salvador Resino
Publikováno v:
Clinical Infectious Diseases. 66:1910-1917
BACKGROUND: Interferon alpha (IFN-α) can potently reduce human immunodeficiency virus type 1 (HIV-1) replication in tissue culture and animal models, but may also modulate residual viral reservoirs that persist despite suppressive antiretroviral com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1457a83309a700c999db51ee423a537
https://doi.org/10.1093/cid/cix1111
https://doi.org/10.1093/cid/cix1111