Výsledky vyhledávání - "Stephane Henriot"

Pharmacological characterisation of the recombinant human CRF binding protein using a simple assay

Autor: Gavin J. Kilpatrick, Roger G. Clerc, Juergen Gottowik, Ali Ardati, Stephane Henriot

Publikováno v: Journal of Neuroscience Methods. 80:99-105

We present the pharmacological characterisation of the recombinant human corticotropin releasing factor binding protein (hCRF-BP) using a simple assay. In this assay we employed [3H]urocortin as the radioligand and, as a means to separate bound and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4ce83a2b8314ddd2eede419c541090
https://doi.org/10.1016/s0165-0270(97)00210-0

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Urocortin: slower dissociation than corticotropin releasing factor from the CRF binding protein

Autor: Gavin J. Kilpatrick, Stephane Henriot, Frank M. Dautzenberg

Publikováno v: European journal of pharmacology. 376(3)

We report on a comparison of the kinetics of [125I][Tyr0]corticotropin releasing factor (CRF) and [125I][Tyr0]urocortin binding to the CRF binding protein (CRF-BP) at physiological temperature. The association rates of [125I][Tyr0]urocortin or [125I]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d6c0db8e3e46767b7fab8fe768445b
https://pubmed.ncbi.nlm.nih.gov/10448894

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Human CRF2 alpha and beta splice variants: pharmacological characterization using radioligand binding and a luciferase gene expression assay

Autor: Valérie Goetschy, Gavin J. Kilpatrick, Juergen Gottowick, Ali Ardati, Ulrich Deuschle, Olivier Valdenaire, Stephane Henriot

Publikováno v: Neuropharmacology. 38(3)

Corticotropin releasing factor (CRF) receptors belong to the super-family of G protein-coupled receptors. These receptors are classified into two subtypes (CRF1 and CRF2). Both receptors are positively coupled to adenylyl cyclase but they have a dist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da503840f7d67e19b2b28a2b47a8046
https://pubmed.ncbi.nlm.nih.gov/10219982

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Labelling of CRF1 and CRF2 receptors using the novel radioligand, [3H]-urocortin

Autor: Roger G. Clerc, Jean-Luc Moreau, Juergen Gottowik, Frederick J. Monsma, Valérie Goetschy, E. Kitas, Stephane Henriot, B. Fluhman, Gavin J. Kilpatrick

Publikováno v: Neuropharmacology. 36(10)

The binding of the novel radioligand, [3H]-rat urocortin to homogenates of rat cerebellum and homogenates of cells stably transfected with the human CRF1, rat CRF2α and rat CRF2β receptors was examined. In each case, specific reversible high affini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c51016ed709508897a0c860af1b38b
https://pubmed.ncbi.nlm.nih.gov/9423932

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S.13.03 Pharmacology of the human CRF1, CRF2α and CRF2β receptors and CRF binding protein

Autor: A. Ardati, Stephane Henriot, Olivier Valdenaire, Jean-Luc Moreau, U. Deuschle, J. Gottowik, T. Giller, V. Breu, Gavin J. Kilpatrick, Valérie Goetschy

Publikováno v: European Neuropsychopharmacology. 7:S103-S104

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8b59e6ff4aec22506ec4d872e04b80d
https://doi.org/10.1016/s0924-977x(97)88401-5

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