Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephane Germain"'
Implantation of engineered human microvasculature to study human infectious diseases in mouse models
Autor:
Sophia Schönherr-Hellec, Eirini Chatzopoulou, Jean-Philippe Barnier, Yoann Atlas, Sébastien Dupichaud, Thomas Guilbert, Yves Dupraz, Julie Meyer, Catherine Chaussain, Caroline Gorin, Xavier Nassif, Stephane Germain, Laurent Muller, Mathieu Coureuil
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106286- (2023)
Summary: Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular cells embedded in collagen hydrogel that allows inv
Externí odkaz:
https://doaj.org/article/42dd2748dbfa4182b28a846f68f9536c
Autor:
Stéphane Germain
Le premier livre qui rend accessible le référentiel de l'UNESCO en EDD. Ce guide propose une démarche d'appropriation du référentiel de l'éducation au développement durable (EDD) de l'UNESCO applicable à l'école primaire, au collège et au l
Autor:
Emmanuelle Guérin, Lisa Belin, Guillaume Franchineau, Loïc Le Guennec, David Hajage, Mamadou Hassimiou Diallo, Thomas Frapard, Lucie Le Fèvre, Charles-Edouard Luyt, Alain Combes, Stéphane Germain, Jan Hayon, Pierre Asfar, Nicolas Bréchot
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-11 (2023)
Abstract Background Vascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under development that stabilizes interendothelial cell junctions, at reducing vascular leakage d
Externí odkaz:
https://doaj.org/article/7d0ee03f3545421d8d48646355d062b0
Publikováno v:
Day 2 Tue, November 14, 2017.
In June 2016, GHGSat launched the world's first satellite capable of measuring greenhouse gas emissions from targeted industrial facilities around the world. We offer a single solution to measure emission rates of carbon dioxide and methane from sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483f12251f8a48c77c5844c01900400e
https://doi.org/10.2118/188398-ms
https://doi.org/10.2118/188398-ms
Autor:
Stephane Germain, Anne-Lise Etter, Marc Dupuis, Bernard Sordat, Jean-François Delaloye, Isabelle Bassi, Jürg Tschopp
Publikováno v:
Gynecologic Oncology. 107:14-21
Objective. MegaFas Ligand (MFL) is a recombinant molecule that efficiently triggers apoptosis after binding to the Fas receptor expressed on target cells. The purpose of this study was to determine the potency of MFL in vitro and efficacy in vivo for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da66ccce724e2e5cf83053158d3579e3
https://doi.org/10.1016/j.ygyno.2007.05.030
https://doi.org/10.1016/j.ygyno.2007.05.030
Autor:
Fawaz Alzaid, Jean‐Baptiste Julla, Marc Diedisheim, Charline Potier, Louis Potier, Gilberto Velho, Bénédicte Gaborit, Philippe Manivet, Stéphane Germain, Tiphaine Vidal‐Trecan, Ronan Roussel, Jean‐Pierre Riveline, Elise Dalmas, Nicolas Venteclef, Jean‐François Gautier
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 10, Pp 1-12 (2020)
Abstract Early in the COVID‐19 pandemic, type 2 diabetes (T2D) was marked as a risk factor for severe disease and mortality. Inflammation is central to the aetiology of both conditions where variations in immune responses can mitigate or aggravate
Externí odkaz:
https://doaj.org/article/7c72d6f547d64ae5b2a37caae2a48163
Publikováno v:
In Archives of Cardiovascular Diseases Supplements April 2015 7(2):148-148
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
In vitro 3D culture systems provide promising tools for screening novel therapies and understanding drug resistance mechanisms in cancer because they are adapted for high throughput analysis. One of the main current challenges is to reproducibly cult
Externí odkaz:
https://doaj.org/article/c38cabd6e1d54993bc81e4acd3bb64de
Autor:
Pierre Ucla, Xingming Ju, Melisa Demircioglu, Sarah Baiz, Laurent Muller, Stéphane Germain, Catherine Monnot, Vincent Semetey, Sylvie Coscoy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2415 (2022)
The understanding of endothelium–extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the mechanobiological principles governing endothelial protrusive behaviours in 3D microtopograph
Externí odkaz:
https://doaj.org/article/0eb9fdc793db467b867fde738cbc49c2
Autor:
Athanasia Liabotis, Corinne Ardidie-Robouant, Philippe Mailly, Samaher Besbes, Charly Gutierrez, Yoann Atlas, Laurent Muller, Stéphane Germain, Catherine Monnot
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 206 (2022)
Angiopoietin-like 4 (ANGPTL4) is a target of hypoxia that accumulates in the endothelial extracellular matrix. While ANGPTL4 is known to regulate angiogenesis and vascular permeability, its context-dependent role related to vascular endothelial growt
Externí odkaz:
https://doaj.org/article/159152695c0644e49df0f40fdb61c507