Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stephane Flamant"'
Autor:
Alexandre Ribault, Mohamed Amine Benadjaoud, Claire Squiban, Laurent Arnaud, Coralie Judicone, Aurélie S. Leroyer, Alexandra Rousseau, Christelle Huet, Chandan Guha, Marc Benderitter, Romaric Lacroix, Stephane Flamant, Emily I. Chen, Jean-Marc Simon, Radia Tamarat
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In a large retrospective study, we assessed the putative use of circulating microvesicles (MVs), as innovative biomarkers of radiation toxicity in a cohort of 208 patients with prostate adenocarcinoma overexposed to radiation. The level of p
Externí odkaz:
https://doaj.org/article/74a0e092cc38444aa0ec420a2040ca5a
Autor:
Sónia Ribeiro, Ana Rita Simões, Filipe Rocha, Inês Sofia Vala, Ana Teresa Pinto, Augusto Ministro, Esmeralda Poli, Isabel Maria Diegues, Filomena Pina, Mohamed Amine Benadjaoud, Stephane Flamant, Radia Tamarat, Hugo Osório, Diogo Pais, Diogo Casal, Fausto José Pinto, Rune Matthiesen, Manuela Fiuza, Susana Constantino Rosa Santos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The contribution of radiotherapy, per se, to late cardiotoxicity remains controversial. To clarify its impact on the development of early cardiac dysfunction, we developed an experimental model in which the hearts of rats were exposed, in a fractiona
Externí odkaz:
https://doaj.org/article/e032c7f38ff34276b9a654e9db40189c
Autor:
Megha Rajasekhar, Ulf Schmitz, Stephane Flamant, Justin J.-L. Wong, Charles G. Bailey, William Ritchie, Jeff Holst, John E. J. Rasko
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Myelopoiesis involves differentiation of hematopoietic stem cells to cellular populations that are restricted in their self-renewal capacity, beginning with the common myeloid progenitor (CMP) and leading to mature cells including monocytes
Externí odkaz:
https://doaj.org/article/5130f8e3f39c40e099172e258a4f2129
Autor:
Valérie Holler, Valerie Buard, Telma Roque, Claire Squiban, Marc Benderitter, Stephane Flamant, Radia Tamarat
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Skin lesions caused by accidental exposure to radiation or by radiotherapy are a major clinical challenge. We evaluated the effect of bone marrow mononuclear cells (BMMNC) on collagen remodeling and vascular function in radiation-induced skin lesions
Externí odkaz:
https://doaj.org/article/392ded8ad62f4fc999537ba17afe1620
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 9, p e1000513 (2009)
microRNAs (miRNAs) are major regulators of gene expression and thereby modulate many biological processes. Computational methods have been instrumental in understanding how miRNAs bind to mRNAs to induce their repression but have proven inaccurate. H
Externí odkaz:
https://doaj.org/article/7dcaf2493fa64d21be11d1ce08ac556b
Autor:
Lucie Ancel, Olivier Gabillot, Chloé Szurewsky, Romain Granger, Amandine Sache, Frédéric Voyer, Gaëtan Gruel, Stéphane Illiano, Marc Benderitter, Bernard Le Guen, Maâmar Souidi, Mohamed Amine Benadjaoud, Stéphane Flamant
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract A radiological accident, whether from industrial, medical, or malicious origin, may result in localized exposure to high doses of ionizing radiations, leading to the development of local radiation injury (LRI), that may evolve toward deep ul
Externí odkaz:
https://doaj.org/article/95b6b1b3eb054219ab9215540f423b78
Autor:
Paul Dumas, Olivier Feraud, Rania Khedhir, Marie-Laure Bonnet, Christophe Desterke, Annelise Bennaceur-Griscelli, Ali G. Turhan, Christophe Sandt, Stephane Flamant, Charles G. Bailey, John E.J. Rasko
Publikováno v:
Biochemical and Biophysical Research Communications. 503:1861-1867
Despite the major success obtained by the use of tyrosine kinase inhibitors (TKI) in chronic myeloid leukemia (CML), resistances to therapies occur due to mutations in the ABL-kinase domain of the BCR-ABL oncogene. Amongst these mutations, the “gat
Autor:
Ulf Schmitz, John E.J. Rasko, Justin J.-L. Wong, Megha Rajasekhar, Charles G. Bailey, Stephane Flamant, Jeff Holst, William Ritchie
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Myelopoiesis involves differentiation of hematopoietic stem cells to cellular populations that are restricted in their self-renewal capacity, beginning with the common myeloid progenitor (CMP) and leading to mature cells including monocytes and granu
Autor:
Céline Loinard, Mohamed Amine Benadjaoud, Bruno Lhomme, Stéphane Flamant, Jan Baijer, Radia Tamarat
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Local overexposure to ionizing radiation leads to chronic inflammation, vascular damage and cachexia. Here we investigate the kinetics of inflammatory cells from day (D)1 to D180 after mouse hindlimb irradiation and analyze the role of monoc
Externí odkaz:
https://doaj.org/article/d99b118c976e4f01ae426b8285043af4
Autor:
M. Peschanski, A. Ribault, Bruno l’Homme, C. Pinset, Stephane Flamant, Jean-Jacques Lataillade, E. Massouridès, Marc Benderitter, Radia Tamarat, E. Busson
Publikováno v:
Cytotherapy. 22:S44
Background & Aim The current management of victims of radiological burns, resulting from industrial or medical accidental exposure, consists in autologous mesenchymal stromal cell (MSC) injection associated with reparative surgery. MSCs were shown to