Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephane Bourg"'
Autor:
Sreenivas Avula, Xudan Peng, Xingfen Lang, Micky Tortorella, Béatrice Josselin, Stéphane Bach, Stephane Bourg, Pascal Bonnet, Frédéric Buron, Sandrine Ruchaud, Sylvain Routier, Cleopatra Neagoie
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1632-1650 (2022)
A library of substituted indolo[2,3-c]quinolone-6-ones was developed as simplified Lamellarin isosters. Synthesis was achieved from indole after a four-step pathway sequence involving iodination, a Suzuki-Miyaura cross-coupling reaction, and a reduct
Externí odkaz:
https://doaj.org/article/eae579ca70af4ec7902f09b889e08fbc
Publikováno v:
Mineral Economics
Mineral Economics, 2022, ⟨10.1007/s13563-022-00338-y⟩
Mineral Economics, 2022, ⟨10.1007/s13563-022-00338-y⟩
International audience; The world’s population is constantly growing, the global standard of living is increasing, urbanisation is developing on all continents and both the digital transformation and the necessary energy transition are underway. Th
Autor:
Giovanni Di Girolamo, Stephane Bourg
Publikováno v:
2018 IEEE International Conference on Environment and Electrical Engineering and 2018 IEEE Industrial and Commercial Power Systems Europe (EEEIC / I&CPS Europe).
SCRREEN project gathers more than 50 European initiatives, associations, organisations or independent experts working on Critical Raw Materials (CRM) into a long lasting Network including stakeholders, public authorities and civil society representat
Autor:
Samia Aci-Sèche, Stéphane Bourg, Pascal Bonnet, Joseph Rebehmed, Alexandre G. de Brevern, Julien Diharce
Publikováno v:
Data in Brief, Vol 49, Iss , Pp 109386- (2023)
Computational approaches are nowadays largely applied in drug discovery projects. Among these, molecular docking is the most used for hit identification against a drug target protein. However, many scientists in the field shed light on the lack of av
Externí odkaz:
https://doaj.org/article/e7585940b50d4c97ab4ca6ad27f5d0b4
Autor:
Stephane Bourgeois, Daniel F. Carr, Crispin O. Musumba, Alexander Penrose, Celestine Esume, Andrew P. Morris, Andrea L. Jorgensen, J. Eunice Zhang, D. Mark Pritchard, Panos Deloukas, Munir Pirmohamed
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103728- (2021)
ABSTRACT: Background: Low-dose aspirin can cause gastric and duodenal ulceration, hereafter called peptic ulcer disease (PUD). Predisposition is thought to be related to clinical and genetic factors; our aim was to identify genetic risk factors assoc
Externí odkaz:
https://doaj.org/article/e356fc46996447cfa33cfd26c73f0564
Autor:
Stavroula Kanoni, Satish Kumar, Charalampia Amerikanou, Mary Jo Kurth, Maria G. Stathopoulou, Stephane Bourgeois, Christine Masson, Aimo Kannt, Lucia Cesarini, Maria-Spyridoula Kontoe, Maja Milanović, Francisco J. Roig, Mirjana Beribaka, Jonica Campolo, Nuria Jiménez-Hernández, Nataša Milošević, Carlos Llorens, Ilias Smyrnioudis, M. Pilar Francino, Nataša Milić, Andriana C. Kaliora, Maria Giovanna Trivella, Mark W. Ruddock, Milica Medić-Stojanoska, Amalia Gastaldelli, John Lamont, Panos Deloukas, George V. Dedoussis, Sophie Visvikis-Siest
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease with no therapeutic consensus. Oxidation and inflammation are hallmarks in the progression of this complex disease, which also involves interactions between the genetic backgr
Externí odkaz:
https://doaj.org/article/01cf24ceb3e947749ca21d7d2aed1f4f
Akademický článek
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Autor:
Camille Chenevier-Gobeaux, Louis Deweerdt, Anne-Valérie Cantero, Bertrand Renaud, Bruno Desmaizières, Sandrine Charpentier, Aline Leroy, Emmanuelle Adelaïde, Delphine Collin-Chavagnac, Eric Bonnefoy-Cudraz, Laurence Estepa, Akli Chekroune, Sylvie Basco, Stéphane Andrieu, Stéphane Bourgeois, Marie-Agnès Costa, Christine Vallejo, Tiphaine Robert, Siham Ouahabi, Bruno Baudin, Benedicte Beneteau-Burnat, Anne-Marie Gorce-Dupuy, Patrick Ray, Claire Gast, Monique Dehoux, Guillaume Lefèvre
Publikováno v:
Practical Laboratory Medicine, Vol 11, Iss , Pp 23-32 (2018)
Objectives: We aimed to compare the use of nine different cardiac troponin (cTn) assays (2 cTnT and 7 cTnI) for the diagnosis of NSTEMI in a single multi-centre population. Design and methods: One hundred and fifty-eight patients were included (mean
Externí odkaz:
https://doaj.org/article/ab12085b3eb643a5ae10afc1d9ed60b6
Autor:
Assaf Gottlieb, Roxana Daneshjou, Marianne DeGorter, Stephane Bourgeois, Peter J. Svensson, Mia Wadelius, Panos Deloukas, Stephen B. Montgomery, Russ B. Altman
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-9 (2017)
Abstract Background Genome-wide association studies are useful for discovering genotype–phenotype associations but are limited because they require large cohorts to identify a signal, which can be population-specific. Mapping genetic variation to g
Externí odkaz:
https://doaj.org/article/261a8c9e0ef54d29a241ab8e535b6302
Autor:
Frédéric Buron, Nuno Rodrigues, Thibault Saurat, Marie Aude Hiebel, Stéphane Bourg, Pascal Bonnet, Reine Nehmé, Philippe Morin, Nathalie Percina, Justine Corret, Béatrice Vallée, Remy le Guevel, Marie-Lise Jourdan, Hélène Bénédetti, Sylvain Routier
Publikováno v:
Molecules, Vol 26, Iss 17, p 5349 (2021)
This work describes the synthesis, enzymatic activities on PI3K and mTOR, in silico docking and cellular activities of various uncommon 2,4,7 trisubstituted pyrido[3,2-d]pyrimidines. The series synthesized offers a chemical diversity in C-7 whereas C
Externí odkaz:
https://doaj.org/article/6a0143f187a1484fb74923056d30d307