Design and biological evaluation of substituted 5,7-dihydro-6H-indolo[2,3-c]quinolin-6-one as novel selective Haspin inhibitors

Autor: Sreenivas Avula, Xudan Peng, Xingfen Lang, Micky Tortorella, Béatrice Josselin, Stéphane Bach, Stephane Bourg, Pascal Bonnet, Frédéric Buron, Sandrine Ruchaud, Sylvain Routier, Cleopatra Neagoie

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1632-1650 (2022)

A library of substituted indolo[2,3-c]quinolone-6-ones was developed as simplified Lamellarin isosters. Synthesis was achieved from indole after a four-step pathway sequence involving iodination, a Suzuki-Miyaura cross-coupling reaction, and a reduct

Externí odkaz: https://doaj.org/article/eae579ca70af4ec7902f09b889e08fbc

Solutions for Critical Raw Materials Supply: Main Activities in the SCRREEN Project

Autor: Giovanni Di Girolamo, Stephane Bourg

Publikováno v: 2018 IEEE International Conference on Environment and Electrical Engineering and 2018 IEEE Industrial and Commercial Power Systems Europe (EEEIC / I&CPS Europe).

SCRREEN project gathers more than 50 European initiatives, associations, organisations or independent experts working on Critical Raw Materials (CRM) into a long lasting Network including stakeholders, public authorities and civil society representat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084fc23066a66dff2332711119cae706
https://doi.org/10.1109/eeeic.2018.8494385

From mineral processing to waste management and recycling: common challenges and needs for innovation in France.

Autor: D'Hugues, Patrick, Bourg, Stephane, Menard, Yannick

Publikováno v: Mineral Economics: Raw Materials Report; Dec2022, Vol. 35 Issue 3/4, p563-567, 5p

Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2- d ]Pyrimidine Series as Novel PI3K/mTOR Inhibitors.

Autor: Buron, Frédéric¹ (AUTHOR) frederic.buron@univ-orleans.fr, Rodrigues, Nuno¹ (AUTHOR) nuno.rodrigues@univ-orleans.fr, Saurat, Thibault^1,2 (AUTHOR) thibault.saurat@univ-orleans.fr, Hiebel, Marie Aude¹ (AUTHOR) marie-aude.hiebel@univ-orleans.fr, Bourg, Stéphane¹ (AUTHOR) stephane.bourg@univ-oleans.fr, Bonnet, Pascal¹ (AUTHOR) pascal.bonnet@univ-orleans.fr, Nehmé, Reine¹ (AUTHOR) reine.nehme@univ-orleans.fr, Morin, Philippe¹ (AUTHOR) philippe.morin@univ-orleans.fr, Percina, Nathalie¹ (AUTHOR) nathalie.percina@univ-orleans.fr, Corret, Justine² (AUTHOR) beatrice.vallee@cnrs.fr, Vallée, Béatrice² (AUTHOR), le Guevel, Remy³ (AUTHOR) remy.leguevel@univ-rennes1.fr, Jourdan, Marie-Lise⁴ (AUTHOR) m.jourdan@chu-tours.fr, Bénédetti, Hélène² (AUTHOR) helene.benedetti@cnrs-orleans.fr, Routier, Sylvain¹ (AUTHOR) helene.benedetti@cnrs-orleans.fr

Publikováno v: Molecules. Sep2021, Vol. 26 Issue 17, p5349. 1p.

Global Progress on Molten Salt Reactors : A Companion to Dolan's Molten Salt Reactors and Thorium Energy

Autor: Thomas James Dolan, John Kutsch

Global Progress on Molten Salt Reactors: A Companion to Dolan's Molten Salt Reactors and Thorium Energy, Second Edition presents global perspectives on the latest research and technological advances. Each case study utilizes a comprehensive template