Výsledky vyhledávání - "Stephane, Potteaux"

Akademický článek

Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Obesity and inflammation have been associated to cancer progression. Here, the authors show that high fat and cholesterol diet, in a non-obese context, promotes tumourigenesis through increasing inflammatory monocytes and myeloid-derived pro-angiogen

Externí odkaz: https://doaj.org/article/9d1b5cbfa4cd4a4690d9acceffb058b5

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Akademický článek

Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet.

Autor: Sarvenaz Metghalchi, Marie Vandestienne, Yacine Haddad, Bruno Esposito, Julien Dairou, Alain Tedgui, Ziad Mallat, Stephane Potteaux, Soraya Taleb

Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0193737 (2018)

AIMS:Abdominal aortic aneurysm (AAA) is an age-associated disease characterized by chronic inflammation, vascular cell apoptosis and metalloproteinase-mediated extracellular matrix degradation. Despite considerable progress in identifying targets inv

Externí odkaz: https://doaj.org/article/f81b7faf65ed4cdd8c45d1997961e44f

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MicroRNA-21 Deficiency Alters the Survival of Ly-6C lo Monocytes in ApoE −/− Mice and Reduces Early-Stage Atherosclerosis—Brief Report

Autor: Mélanie Montabord, Stephane Potteaux, Alain Tedgui, Anna Chipont, Ziad Mallat, Xavier Loyer, Bruno Esposito, Inès Challier

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 39:170-177

Objective— To determine the role of microRNA-21 (miR-21) on the homeostasis of monocyte subsets and on atherosclerosis development in ApoE −/− (apolipoprotein E) mice. Approach and Results— In ApoE −/− mice, miR-21 expression was increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b5fa04176b3f45d59f1498ec433fa22
https://doi.org/10.1161/atvbaha.118.311942

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Pro-atherogenic diet accelerates tumor growth in mice through IL-1β and myeloid cell-derived VEGF-A

Autor: Thi Tran, Christian Stockmann, Bruno Esposito, Olivia Lenoir, Jaouen Tran Rajau, Hafid Ait-Oufella, Mélanie Montabord, Alain Tedgui, Ziad Mallat, Stephane Potteaux, Nadège Gruel, Eric Tartour

Aims: Myeloid inflammatory cells are recruited to the tumor microenvironment and subsequently educated in situ to acquire a pro-invasive, pro-angiogenic and immunosuppressive phenotype. Components of the metabolic syndrome are known to aggravate tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd260a023477b4909d3373689848e570
https://doi.org/10.21203/rs.3.rs-86825/v1

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Akademický článek

Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy.

Autor: Abigail S Haka, Stephane Potteaux, Haley Fraser, Gwendalyn J Randolph, Frederick R Maxfield

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e44823 (2012)

The progressive accumulation of monocyte-derived cells in the atherosclerotic plaque is a hallmark of atherosclerosis. However, it is now appreciated that monocytes represent a heterogeneous circulating population of cells that differ in functionalit

Externí odkaz: https://doaj.org/article/1ba77e2cda124b30a540d24e86619577

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Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis

Autor: Sébastien Gibot, Saskia C.A. de Jager, Marie Vandestienne, Xavier Loyer, Carole Hénique, Ivana Zlatanova, Jérémie Joffre, Ludivine Laurans, Stephane Potteaux, Patrick Bruneval, Lynda Zeboudj, Bruno Esposito, Amir Boufenzer, Hafid Ait-Oufella, Alain Tedgui, Soraya Taleb, Ziad Mallat

Publikováno v: Journal of the American College of Cardiology, 68(25), 2776. Elsevier USA

Background Innate immune responses activated through myeloid cells contribute to the initiation, progression, and complications of atherosclerosis in experimental models. However, the critical upstream pathways that link innate immune activation to f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbc1a27cc97858c1a2dac7fa8706431
https://doi.org/10.1016/j.jacc.2016.10.015

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Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant

Autor: Martin, Steinmetz, Ludivine, Laurans, Sarah, Nordsiek, Lena, Weiß, Bieke, van der Veken, Padmapriya, Ponnuswamy, Bruno, Esposito, Marie, Vandestienne, Andreas, Giraud, Cristina, Göbbel, Eva, Steffen, Tobias, Radecke, Stephane, Potteaux, Georg, Nickenig, Tienush, Rassaf, Alain, Tedgui, Ziad, Mallat

Publikováno v: Journal of Cellular and Molecular Medicine

Adaptive immune responses regulate the development of atherosclerosis, with a detrimental effect of type 1 but a protective role of type 2 immune responses. Immunization of Apolipoprotein E‐deficient (ApoE−/−) mice with Freund's adjuvant inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd6fd4c6c4ad67b520c601ad2e2b1681
https://pubmed.ncbi.nlm.nih.gov/32285594

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