Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Stephana Carelli"'
Autor:
Giovanni Buccioli, Carolina Testa, Emanuela Jacchetti, Pietro Pinoli, Stephana Carelli, Stefano Ceri, Manuela T. Raimondi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Statins, widely used cardiovascular drugs that lower cholesterol by inhibiting HMG-CoA reductase, have been increasingly recognized for their potential anticancer properties. This study elucidates the underlying mechanism, revealing that sta
Externí odkaz:
https://doaj.org/article/0c1f53cca6b34826820d8f66486621c7
Autor:
Serena Mazzucchelli, Lorena Signati, Letizia Messa, Alma Franceschini, Arianna Bonizzi, Lorenzo Castagnoli, Patrizia Gasparini, Clarissa Consolandi, Eleonora Mangano, Paride Pelucchi, Ingrid Cifola, Tania Camboni, Marco Severgnini, Laura Villani, Barbara Tagliaferri, Stephana Carelli, Serenella M. Pupa, Cristina Cereda, Fabio Corsi
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background A reliable preclinical model of patient-derived organoids (PDOs) was developed in a case study of a 69-year-old woman diagnosed with breast cancer (BC) to investigate the tumour evolution before and after neoadjuvant chemotherapy
Externí odkaz:
https://doaj.org/article/87a0c667c3c14d669d41b5cdc4ebd64b
Autor:
Alessia Casamassa, Giovannina Rotundo, Chiara Ceresoni, Elisa Maria Turco, Isabella Torrente, Ornella Candido, Francesco Nicita, Davide Tonduti, Enrico Bertini, Massimo Marano, Daniela Ferrari, Cristina Cereda, Maria Pennuto, Angelo Luigi Vescovi, Stephana Carelli, Jessica Rosati
Publikováno v:
Stem Cell Research, Vol 78, Iss , Pp 103468- (2024)
Hypomyelinating leukodystrophies (HLD) are a group of heterogeneous genetic disorders characterized by a deficit in myelin deposition during brain development. Specifically, 4H-Leukodystrophy is a recessive disease due to biallelic mutations in the P
Externí odkaz:
https://doaj.org/article/0f7761d770824ef197fd91d880bd73f6
Autor:
Alessia Mauri, Clarissa Berardo, Davide Biganzoli, Andrea Meta, Sara Benedetti, Federica Rey, Letizia Messa, Gian Vincenzo Zuccotti, Stephana Carelli, Luisella Alberti, Cristina Cereda
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 39, Iss , Pp 101074- (2024)
Each year thousands of babies are born with rare genetic disorders not identified by current NBS panels, due to programs which are not yet optimal. Next-generation sequencing technologies have the potential to overcome many NBS drawbacks and provide
Externí odkaz:
https://doaj.org/article/131aec9bb5ee4203b3458d7620276936
Autor:
Sofian Al Wardat, Loredana Frassinelli, Elisa Orecchini, Federica Rey, Silvia Anna Ciafrè, Silvia Galardi, Jessica Garau, Stella Gagliardi, Simona Orcesi, Davide Tonduti, Stephana Carelli, Cristina Cereda, Ernesto Picardi, Alessandro Michienzi
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101028- (2024)
Externí odkaz:
https://doaj.org/article/28619eea9a654d04b5eefdeabe87eb70
Autor:
Letizia Messa, Carolina Testa, Stephana Carelli, Federica Rey, Emanuela Jacchetti, Cristina Cereda, Manuela Teresa Raimondi, Stefano Ceri, Pietro Pinoli
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9576 (2024)
The vast corpus of heterogeneous biomedical data stored in databases, ontologies, and terminologies presents a unique opportunity for drug design. Integrating and fusing these sources is essential to develop data representations that can be analyzed
Externí odkaz:
https://doaj.org/article/0a537d4b50914b828990419618625022
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1187-1188 (2024)
Externí odkaz:
https://doaj.org/article/b14b4a7ae2514a8794d39b04b9515a86
Autor:
Marta Sevieri, Serena Mazzucchelli, Linda Barbieri, Stefania Garbujo, Stephana Carelli, Arianna Bonizzi, Federica Rey, Camilla Recordati, Matteo Recchia, Raffaele Allevi, Leopoldo Sitia, Carlo Morasso, Pietro Zerbi, Davide Prosperi, Fabio Corsi, Marta Truffi
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106934- (2023)
Brain metastasis (BM) represents a clinical challenge for patients with advanced HER2 + breast cancer (BC). The monoclonal anti-HER2 antibody trastuzumab (TZ) improves survival of BC patients, but it has low central nervous system penetrance, being i
Externí odkaz:
https://doaj.org/article/a4369cca99084dba888ec5c9ebbf0ccd
Autor:
Francesca Donnaloja, Manuela Teresa Raimondi, Letizia Messa, Bianca Barzaghini, Federica Carnevali, Emanuele Colombo, Davide Mazza, Chiara Martinelli, Lucia Boeri, Federica Rey, Cristina Cereda, Roberto Osellame, Giulio Cerullo, Stephana Carelli, Monica Soncini, Emanuela Jacchetti
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 036112-036112-21 (2023)
Mechanical stimuli from the extracellular environment affect cell morphology and functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown in a custom-made 3D microscaffold, the Nichoid, are able to express higher levels of stemne
Externí odkaz:
https://doaj.org/article/82830f1396af455493f63e4478316e2c
Autor:
Maxime Bonnet, Céline Ertlen, Mostafa Seblani, Jean-Michel Brezun, Thelma Coyle, Cristina Cereda, Gianvincenzo Zuccotti, Mattia Colli, Christophe Desouches, Patrick Decherchi, Stephana Carelli, Tanguy Marqueste
Publikováno v:
Cells, Vol 13, Iss 2, p 182 (2024)
Traumatic spinal cord injuries (SCIs) often result in sensory, motor, and vegetative function loss below the injury site. Although preclinical results have been promising, significant solutions for SCI patients have not been achieved through translat
Externí odkaz:
https://doaj.org/article/5be83b175c2843f09eee5933e1c716f0