Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stephan Woditschka"'
Autor:
Brunilde Gril, Anurag N. Paranjape, Stephan Woditschka, Emily Hua, Emma L. Dolan, Jeffrey Hanson, Xiaolin Wu, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Rafał Pęksa, Wojciech Biernat, Jacek Jassem, Naema Nayyar, Priscilla K. Brastianos, O. Morgan Hall, Cody J. Peer, William D. Figg, Gary T. Pauly, Christina Robinson, Simone Difilippantonio, Emilie Bialecki, Philippe Metellus, Joel P. Schneider, Patricia S. Steeg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
When brain metastases form, the blood–brain barrier morphs into the blood–tumor barrier (BTB), surrounded by neuroinflammatory response. Here, the authors show that S1P3 is upregulated in neuroinflammatory response in highly BTB permeable lesions
Externí odkaz:
https://doaj.org/article/69cb9612d00a46d3a48171a71ecd0d7b
Autor:
Patricia S. Steeg, Jacek Jassem, Seth M. Steinberg, David J. Liewehr, Stephen M. Hewitt, Andreas M. Stark, Brunilde Gril, Katarzyna Sosińska-Mielcarek, Wojciech Biernat, Yongzhen Qian, Emily Hua, Stephan Woditschka, Renata Duchnowska, Diane Palmieri
PDF file - 113KB, MGMT expression status in Jimt-1-Br3 cells predicts sensitivity to temozolomide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fdb68ad1ef7515d3c4d98d0f850709
https://doi.org/10.1158/1078-0432.22449878
https://doi.org/10.1158/1078-0432.22449878
Autor:
Patricia S. Steeg, Jacek Jassem, Seth M. Steinberg, David J. Liewehr, Stephen M. Hewitt, Andreas M. Stark, Brunilde Gril, Katarzyna Sosińska-Mielcarek, Wojciech Biernat, Yongzhen Qian, Emily Hua, Stephan Woditschka, Renata Duchnowska, Diane Palmieri
PDF file - 96KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e127b59381ef2175b7c010cd33f41f0
https://doi.org/10.1158/1078-0432.22449872.v1
https://doi.org/10.1158/1078-0432.22449872.v1
Autor:
Patricia S. Steeg, Jacek Jassem, Seth M. Steinberg, David J. Liewehr, Stephen M. Hewitt, Andreas M. Stark, Brunilde Gril, Katarzyna Sosińska-Mielcarek, Wojciech Biernat, Yongzhen Qian, Emily Hua, Stephan Woditschka, Renata Duchnowska, Diane Palmieri
Purpose: Brain metastases of breast cancer cause neurocognitive damage and are incurable. We evaluated a role for temozolomide in the prevention of brain metastases of breast cancer in experimental brain metastasis models.Experimental Design: Temozol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb33fc0b63bdad27500000a3497119b
https://doi.org/10.1158/1078-0432.c.6521783
https://doi.org/10.1158/1078-0432.c.6521783
Autor:
Patricia S. Steeg, Jacek Jassem, Seth M. Steinberg, David J. Liewehr, Stephen M. Hewitt, Andreas M. Stark, Brunilde Gril, Katarzyna Sosińska-Mielcarek, Wojciech Biernat, Yongzhen Qian, Emily Hua, Stephan Woditschka, Renata Duchnowska, Diane Palmieri
PDF file - 67KB, MGMT overexpression in 231-BR-EGFP cells increases sensitivity to temozolomide in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ca687049f8838b3024df9e8107c14e
https://doi.org/10.1158/1078-0432.22449881
https://doi.org/10.1158/1078-0432.22449881
Autor:
Patricia S. Steeg, Jacek Jassem, Seth M. Steinberg, David J. Liewehr, Stephen M. Hewitt, Andreas M. Stark, Brunilde Gril, Katarzyna Sosińska-Mielcarek, Wojciech Biernat, Yongzhen Qian, Emily Hua, Stephan Woditschka, Renata Duchnowska, Diane Palmieri
PDF file - 96KB, MGMT expression in matched sets of human breast primary tumors and resected brain metastases does not affect overall patient survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e4bce33291b78af34995e417925048
https://doi.org/10.1158/1078-0432.22449875.v1
https://doi.org/10.1158/1078-0432.22449875.v1
Autor:
Wojciech Kloc, O Morgan Hall, Emily Hua, Rafał Pęksa, Wojciech Biernat, Xiaolin Wu, Philippe Metellus, Naema Nayyar, Jeffrey C. Hanson, Anurag N. Paranjape, Gary T. Pauly, Patricia S. Steeg, Emma L. Dolan, Cody J. Peer, Brunilde Gril, Joel P. Schneider, Stephan Woditschka, Jacek Jassem, William D. Figg, Simone Difilippantonio, Renata Duchnowska, Emilie Bialecki, Ewa Izycka-Swieszewska, Christina Robinson, Priscilla K. Brastianos
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Nature Communications
Nature Communications
Brain metastases are devastating complications of cancer. The blood–brain barrier (BBB), which protects the normal brain, morphs into an inadequately characterized blood–tumor barrier (BTB) when brain metastases form, and is surrounded by a neuro
Autor:
William D. Figg, Joel P. Schneider, Priscilla K. Brastianos, Jeffrey C. Hanson, Anurag N. Paranjape, Xiaolin Wu, Gary T. Pauly, Patricia S. Steeg, Stephan Woditschka, Cody J. Peer, Brunilde Gril, Renata Duchnowska
Breast cancer brain metastases are incurable. The blood-brain barrier (BBB) is a multicellular dynamic structure regulating exchanges between the blood and the central nervous system. As cancer cells colonize the brain, the BBB evolves into a blood-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb195ddf6beaf80a23b61dfdddd1a355
https://europepmc.org/articles/PMC5693203/
https://europepmc.org/articles/PMC5693203/
Autor:
Brunilde Gril, Anurag N Paranjape, Stephan Woditschka, Jeffrey Hanson, Xiaolin Wu, Renata Duchnowska, Priscilla K Brastianos, Cody Peer, William D Figg, Gary T Pauly, Joel P Schneider, Patricia S Steeg
Breast cancer brain metastases are incurable. The blood-brain barrier (BBB) is a multicellular dynamic structure regulating exchanges between the blood and the central nervous system. As cancer cells colonize the brain, the BBB evolves into a blood-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1478d0a38695ea5f7a0dbc2c971ca8
https://europepmc.org/articles/PMC5692950/
https://europepmc.org/articles/PMC5692950/
Autor:
Brunilde Gril, Stephan Woditschka, Diane Palmieri, Katarzyna Sosińska-Mielcarek, P. S. Steeg, David J. Liewehr, Stephen M. Hewitt, Emily Hua, Seth M. Steinberg, W. Biernat, Andreas M. Stark, Renata Duchnowska, Jacek Jassem, Yongzhen Qian
Publikováno v:
Clinical Cancer Research. 20:2727-2739
Purpose: Brain metastases of breast cancer cause neurocognitive damage and are incurable. We evaluated a role for temozolomide in the prevention of brain metastases of breast cancer in experimental brain metastasis models. Experimental Design: Temozo