Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephan Winklmeier"'
Autor:
Stephan Winklmeier, Heike Rübsamen, Ceren Özdemir, Paul R. Wratil, Gaia Lupoli, Marcel Stern, Celine Schneider, Katharina Eisenhut, Samantha Ho, Hoi Kiu Wong, Damla Taskin, Marvin Petry, Michael Weigand, Peter Eichhorn, Bärbel U. Foesel, Simone Mader, Oliver T. Keppler, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The mucosal immunity is crucial for restricting SARS-CoV-2 at its entry site. Intramuscularly applied vaccines against SARS-CoV-2 stimulate high levels of neutralizing Abs in serum, but the impact of these intramuscular vaccinations on features of mu
Externí odkaz:
https://doaj.org/article/9d42e7c5f3d24fc18847cc55adb70e1e
Autor:
Ramona Gerhards, Lena Kristina Pfeffer, Jessica Lorenz, Laura Starost, Luise Nowack, Franziska S. Thaler, Miriam Schlüter, Heike Rübsamen, Caterina Macrini, Stephan Winklmeier, Simone Mader, Mattias Bronge, Hans Grönlund, Regina Feederle, Hung-En Hsia, Stefan F. Lichtenthaler, Juliane Merl-Pham, Stefanie M. Hauck, Tanja Kuhlmann, Isabel J. Bauer, Eduardo Beltran, Lisa Ann Gerdes, Aleksandra Mezydlo, Amit Bar-Or, Brenda Banwell, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Hans Lassmann, Tania Kümpfel, Naoto Kawakami, Edgar Meinl
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Autoimmune disorders of the central nervous system (CNS) comprise a broad spectrum of clinical entities. The stratification of patients based on the recognized autoantigen is of great importance for therapy optimization and for concepts of p
Externí odkaz:
https://doaj.org/article/48e9a477e7444c7f8deb69565051b888
Autor:
Stephan Winklmeier, Katharina Eisenhut, Damla Taskin, Heike Rübsamen, Ramona Gerhards, Celine Schneider, Paul R. Wratil, Marcel Stern, Peter Eichhorn, Oliver T. Keppler, Matthias Klein, Simone Mader, Tania Kümpfel, Edgar Meinl
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103659- (2022)
Summary: Although some COVID-19 patients maintain SARS-CoV-2-specific serum immunoglobulin G (IgG) for more than 6 months postinfection, others eventually lose IgG levels. We assessed the persistence of SARS-CoV-2-specific B cells in 17 patients, 5 o
Externí odkaz:
https://doaj.org/article/421780233e7e4232a603f35bf55f7e8d
Autor:
Stefan Preisendörfer, Yoshihiro Ishikawa, Elisabeth Hennen, Stephan Winklmeier, Jonas C. Schupp, Larissa Knüppel, Isis E. Fernandez, Leonhard Binzenhöfer, Andrew Flatley, Brenda M. Juan-Guardela, Clemens Ruppert, Andreas Guenther, Marion Frankenberger, Rudolf A. Hatz, Nikolaus Kneidinger, Jürgen Behr, Regina Feederle, Aloys Schepers, Anne Hilgendorff, Naftali Kaminski, Edgar Meinl, Hans Peter Bächinger, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Publikováno v:
Cells, Vol 11, Iss 8, p 1341 (2022)
Antibodies are central effectors of the adaptive immune response, widespread used therapeutics, but also potentially disease-causing biomolecules. Antibody folding catalysts in the plasma cell are incompletely defined. Idiopathic pulmonary fibrosis (
Externí odkaz:
https://doaj.org/article/eee505bfb71a48c3bf92f6658efc3879
Autor:
Iris Marti Fernandez, Caterina Macrini, Markus Krumbholz, Paul J. Hensbergen, Agnes L. Hipgrave Ederveen, Stephan Winklmeier, Atay Vural, Asli Kurne, Dieter Jenne, Frits Kamp, Lisa Ann Gerdes, Reinhard Hohlfeld, Manfred Wuhrer, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and polyclonal anti-MOG responses fr
Externí odkaz:
https://doaj.org/article/0625c6d85031465797b02e7849f31245
Autor:
Simone Mader, Samantha Ho, Hoi Kiu Wong, Selia Baier, Stephan Winklmeier, Carolina Riemer, Heike Rübsamen, Iris Marti Fernandez, Ramona Gerhards, Cuilian Du, Omar Chuquisana, Jan D. Lünemann, Anja Lux, Falk Nimmerjahn, Monika Bradl, Naoto Kawakami, Edgar Meinl
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) have recently been established to define a new disease entity, MOG-antibody-associated disease (MOGAD), which is clinically overlapping with multiple sclerosis. MOG-specific antibodies
Autor:
Arek Kendirli, Clara de la Rosa, Katrin F. Lämmle, Klara Eglseer, Isabel J. Bauer, Vladyslav Kavaka, Stephan Winklmeier, Christian Wichmann, Lisa-Ann Gerdes, Tania Kümpfel, Klaus Dornmair, Eduardo Beltrán, Martin Kerschensteiner, Naoto Kawakami
SUMMARYMultiple sclerosis (MS) is a neuroinflammatory disease initiated by the infiltration of autoreactive T cells into the central nervous system (CNS). Several molecules that modulate T cell CNS infiltration in MS have been identified, but how the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92a8f759594ede63c23be8f2965e31cf
https://doi.org/10.1101/2022.06.17.496548
https://doi.org/10.1101/2022.06.17.496548
Autor:
Simone Mader, Lena Bergmann, Michaela Smolle, Dieter E. Jenne, Stephan Winklmeier, Henri G. Franquelim, Edgar Meinl, Reinhard Hohlfeld, Caterina Macrini, Tania Kümpfel, Melania Spadaro, Atay Vural, Ramona Gerhards, Stefan F. Lichtenthaler
Publikováno v:
Brain
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Antibodies to myelin oligodendrocyte glycoprotein (MOG-Abs) define a distinct disease entity. Here we aimed to understand essential structural features of MOG required for recognition by autoantibodies from patients. We produced the N-terminal part o
Autor:
Michelle Biljecki, Katharina Eisenhut, Eduardo Beltrán, Stephan Winklmeier, Simone Mader, Anna Thaller, Peter Eichhorn, Philipp Steininger, Andrea Flierl-Hecht, Jan Lewerenz, Tania Kümpfel, Martin Kerschensteiner, Edgar Meinl, Franziska S. Thaler
Publikováno v:
Neurology - Neuroimmunology Neuroinflammation. 10:e200090
Background and ObjectivesAntibodies (Abs) against the cytoplasmic protein glutamic acid decarboxylase 65 (GAD65) are detected in patients with neurologic syndromes together referred to as GAD65-Ab spectrum disorders. The response of some of these pat
Autor:
Edgar Meinl, Eva Oswald, Miriam Schlüter, Stephan Winklmeier, Tania Kümpfel, Ingrid Meinl, Joachim Havla, Peter Eichhorn
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectivesTo evaluate the long-term effects of natalizumab (NTZ) on different features of intrathecal immunoglobulin (Ig) synthesis in patients with multiple sclerosis (MS) and to quantify the expression of α4-integrin in stages of B-cell maturation