Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Stephan Wilkens"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/96a1080728764f57b9c815e9cc0a2277
Autor:
Lee S Parsons, Stephan Wilkens
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46960 (2012)
BACKGROUND:Vacuolar (H(+))-ATPase (V-ATPase; V(1)V(o)-ATPase) is a large multisubunit enzyme complex found in the endomembrane system of all eukaryotic cells where its proton pumping action serves to acidify subcellular organelles. In the plasma memb
Externí odkaz:
https://doaj.org/article/ff9b2dedcf3347ada49649c744624853
Publikováno v:
BioEssays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5d9a03a5d2257cc98d039b3873831d
https://doi.org/10.1002/bies.202200251
https://doi.org/10.1002/bies.202200251
Autor:
Sijin Luozhong, Zhefan Yuan, Tara Sarmiento, Yu Chen, Wenchao Gu, Caleb McCurdy, Wenting Gao, Ruoxin Li, Stephan Wilkens, Shaoyi Jiang
Publikováno v:
Nano letters. 22(20)
Secondary lymphoid organs (SLOs) are an important target for mRNA delivery in various applications. While the current delivery method relies on the drainage of nanoparticles to lymph nodes by intramuscular (IM) or subcutaneous (SC) injections, an eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06407d98b3e04d8173201104f47cd31
https://pubmed.ncbi.nlm.nih.gov/36194390
https://pubmed.ncbi.nlm.nih.gov/36194390
Publikováno v:
Journal of Biological Chemistry. 294:6439-6449
The vacuolar H+-ATPase (V-ATPase; V1Vo-ATPase) is an ATP-dependent proton pump that acidifies subcellular compartments in all eukaryotic organisms. V-ATPase activity is regulated by reversible disassembly into autoinhibited V1-ATPase and Vo proton ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1431f47eb307a3f6b920aef25f03b71c
https://doi.org/10.1074/jbc.ra119.007577
https://doi.org/10.1074/jbc.ra119.007577
Publikováno v:
The Journal of Biological Chemistry
Aggregation of the circulating protein leukocyte-cell-derived chemotaxin 2 (LECT2) causes amyloidosis of LECT2 (ALECT2), one of the most prevalent forms of systemic amyloidosis affecting the kidney and liver. The I40V mutation is thought to be necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e5b021537ca19af8551bf9b740106d
https://pubmed.ncbi.nlm.nih.gov/33617884
https://pubmed.ncbi.nlm.nih.gov/33617884
Publikováno v:
Encyclopedia of Biological Chemistry III ISBN: 9780128220405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8bfa64c2c920d4b2b185c05edc5397
https://doi.org/10.1016/b978-0-12-819460-7.00307-8
https://doi.org/10.1016/b978-0-12-819460-7.00307-8
Autor:
Wah Chiu, Mrinal Shekhar, Abhishek Singharoy, Stephan Wilkens, Soung Hun Roh, Grigore D. Pintilie, Christophe Chipot
Publikováno v:
Science Advances. 6
Rotary vacuolar adenosine triphosphatases (V-ATPases) drive transmembrane proton transport through a Vo proton channel subcomplex. Despite recent high-resolution structures of several rotary ATPases, the dynamic mechanism of proton pumping remains el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7efcf4fde0a3762e7d46346a157e3a4e
https://doi.org/10.1126/sciadv.abb9605
https://doi.org/10.1126/sciadv.abb9605
Autor:
Soung-Hun, Roh, Mrinal, Shekhar, Grigore, Pintilie, Christophe, Chipot, Stephan, Wilkens, Abhishek, Singharoy, Wah, Chiu
Publikováno v:
Science Advances
A 2.7-Å cryo-EM structure and MD simulations explain water-mediated H+ transport and autoinhibition of yeast Vo proton channel.
Rotary vacuolar adenosine triphosphatases (V-ATPases) drive transmembrane proton transport through a Vo proton chann
Rotary vacuolar adenosine triphosphatases (V-ATPases) drive transmembrane proton transport through a Vo proton chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2149756e1d0be947a66e77ff36d46b39
https://pubmed.ncbi.nlm.nih.gov/33028525
https://pubmed.ncbi.nlm.nih.gov/33028525
Publikováno v:
Journal of Biological Chemistry. 293:10718-10730
Vacuolar H+-ATPases (V-ATPases; V1Vo-ATPases) are rotary-motor proton pumps that acidify intracellular compartments and, in some tissues, the extracellular space. V-ATPase is regulated by reversible disassembly into autoinhibited V1-ATPase and Vo pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fd0343e4c28a9858ecf8b1c7e7a248
https://doi.org/10.1074/jbc.ra118.002951
https://doi.org/10.1074/jbc.ra118.002951