Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Stephan W Schwarzacher"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135493 (2015)
Adult neurogenesis is frequently studied in the mouse hippocampus. We examined the morphological development of adult-born, immature granule cells in the suprapyramidal blade of the septal dentate gyrus over the period of 7-77 days after mitosis with
Externí odkaz:
https://doaj.org/article/835dcb0286994194af98620d0c7d8258
Autor:
Alexandra Vogel, Timo Ueberbach, Annett Wilken-Schmitz, Lisa Hahnefeld, Luisa Franck, Marc-Philipp Weyer, Tassilo Jungenitz, Tobias Schmid, Giulia Buchmann, Florian Freudenberg, Ralf P. Brandes, Robert Gurke, Stephan W. Schwarzacher, Gerd Geisslinger, Thomas Mittmann, Irmgard Tegeder
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-24 (2023)
Abstract Background Pain in early life may impact on development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of “early-life-pain” (ELP) using mice with transgenic expression of channelrhodopsin-2 (ChR2) under contro
Externí odkaz:
https://doaj.org/article/1360257bc91b435c8db71bf01203a661
Autor:
Nina Rößler, Tassilo Jungenitz, Albrecht Sigler, Alexander Bird, Martin Mittag, Jeong Seop Rhee, Thomas Deller, Hermann Cuntz, Nils Brose, Stephan W. Schwarzacher, Peter Jedlicka
Publikováno v:
Open Biology, Vol 13, Iss 8 (2023)
Dendritic spines are crucial for excitatory synaptic transmission as the size of a spine head correlates with the strength of its synapse. The distribution of spine head sizes follows a lognormal-like distribution with more small spines than large on
Externí odkaz:
https://doaj.org/article/bd78c7109d364e9c9d436be340b75e5d
Autor:
Tassilo Jungenitz, Alexander Bird, Maren Engelhardt, Peter Jedlicka, Stephan W. Schwarzacher, Thomas Deller
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
The axon initial segment (AIS) is the site of action potential initiation and important for the integration of synaptic input. Length and localization of the AIS are dynamic, modulated by afferent activity and contribute to the homeostatic control of
Externí odkaz:
https://doaj.org/article/db502a10667946dfb9a06d1c1d87e54c
Autor:
Alexandra Vogel, Timo Ueberbach, Annett Wilken-Schmitz, Lisa Hahnefeld, Luisa Franck, Marc-Philipp Weyer, Tassilo Jungenitz, Tobias Schmid, Giulia Buchmann, Florian Freudenberg, Ralf P. Brandes, Robert Gurke, Stephan W. Schwarzacher, Gerd Geisslinger, Thomas Mittmann, Irmgard Tegeder
Pain in early life may affect cortical development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of "early-life-pain" (ELP) using mice with transgenic expression of channelrhodopsin-2 (ChR2) under control of the Advillin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d383ead2e7cc3c8cbbaada7fedd124
https://doi.org/10.21203/rs.3.rs-2560826/v1
https://doi.org/10.21203/rs.3.rs-2560826/v1
Autor:
Stephan W. Schwarzacher, Matej Vnencak, Angelo Ippolito, Peter Jedlicka, Dilja Krueger-Burg, Tassilo Jungenitz, Julia Muellerleile
Publikováno v:
Molecular Neurobiology. 59:1098-1111
Neuroligin-3 (Nlgn3), a neuronal adhesion protein implicated in autism spectrum disorder (ASD), is expressed at excitatory and inhibitory postsynapses and hence may regulate neuronal excitation/inhibition balance. To test this hypothesis, we recorded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75453641b18b700043f597661b0eacb
https://doi.org/10.1007/s12035-021-02663-9
https://doi.org/10.1007/s12035-021-02663-9
Autor:
Julia Muellerleile, Matej Vnencak, Mohammad Valeed Ahmed Sethi, Tassilo Jungenitz, Stephan W. Schwarzacher, Peter Jedlicka
Publikováno v:
eneuro. 10:ENEURO.0471-22.2023
Loss-of-function mutations in neuroligin-4 (Nlgn4), a member of the neuroligin family of postsynaptic adhesion proteins, cause autism spectrum disorder in humans. Nlgn4 knockout (KO) in mice leads to social behavior deficits and complex alterations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6539c81c1c8fc5c0f8281af7e017fd24
https://doi.org/10.1523/eneuro.0471-22.2023
https://doi.org/10.1523/eneuro.0471-22.2023
Autor:
Julia, Muellerleile, Aline, Blistein, Astrid, Rohlmann, Frederieke, Scheiwe, Markus, Missler, Stephan W, Schwarzacher, Peter, Jedlicka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Deletion of the autism candidate molecule neurobeachin (Nbea), a large PH-BEACH-domain containing neuronal protein, has been shown to affect synaptic function by interfering with neurotransmitter receptor targeting and dendritic spine formation. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::48416338fd44edab5c65c41f65562b2b
http://link.springer.com/article/10.1038/s41598-020-72925-4
http://link.springer.com/article/10.1038/s41598-020-72925-4
Publikováno v:
Brain, behavior, and immunity. 97
The continuous generation of new neurons occurs in at least two well-defined niches in the adult rodent brain. One of these areas is the subgranular zone of the dentate gyrus (DG) in the hippocampus. While the DG is associated with contextual and spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31db5c7356499abada4daba5859b57d4
https://pubmed.ncbi.nlm.nih.gov/34794849
https://pubmed.ncbi.nlm.nih.gov/34794849
Publikováno v:
Brain, Behavior, and Immunity. 99:412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590ef95fc4297a01a3cde50143bf5003
https://doi.org/10.1016/j.bbi.2021.11.004
https://doi.org/10.1016/j.bbi.2021.11.004