Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Stephan W Morris"'
Autor:
Kenichi Harano, Ying Wang, Bora Lim, Robert S Seitz, Stephan W Morris, Daniel B Bailey, David R Hout, Rachel L Skelton, Brian Z Ring, Hiroko Masuda, Arvind U K Rao, Steven Van Laere, Francois Bertucci, Wendy A Woodward, James M Reuben, Savitri Krishnamurthy, Naoto T Ueno
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204513 (2018)
In patients with triple-negative breast cancer (TNBC), tumor-infiltrating lymphocytes (TILs) are associated with improved survival. Lehmann et al. identified 4 molecular subtypes of TNBC [basal-like (BL) 1, BL2, mesenchymal (M), and luminal androgen
Externí odkaz:
https://doaj.org/article/d68e3061b3564009845c351904eed6a8
Autor:
Amy W Lasek, Jana Lim, Christopher L Kliethermes, Karen H Berger, Geoff Joslyn, Gerry Brush, Liquan Xue, Margaret Robertson, Monica S Moore, Karen Vranizan, Stephan W Morris, Marc A Schuckit, Raymond L White, Ulrike Heberlein
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22636 (2011)
Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in various human cancers. We have determined that Alk is associated with altered behavioral r
Externí odkaz:
https://doaj.org/article/a85a1905315e4389912e69a18a2d5452
Autor:
Kamaleldin E. Elagib, Ashton Brock, Cara M. Clementelli, Goar Mosoyan, Lorrie L. Delehanty, Ranjit K. Sahu, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, Stephan W. Morris, Koji Eto, Chintan Jobaliya, Deborah L. French, Paul Gadue, Sandeep Singh, Xinrui Shi, Fujun Qin, Robert Cornelison, Hui Li, Camelia Iancu-Rubin, Adam N. Goldfarb
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of hyperproliferation, limited morphogenesis, and low platelet production capacity. These properties contribute to clinical problems that include thrombocytopeni
Externí odkaz:
https://doaj.org/article/69ea6d3c7d304f89842bbed7338e9cbe
Autor:
Yongwei Zheng, Mei Yu, Yuhong Chen, Liquan Xue, Wen Zhu, Guoping Fu, Stephan W. Morris, Renren Wen, Demin Wang
Publikováno v:
The Journal of Immunology. 210:1222-1235
The caspase recruitment domain family member (CARD)11-Bcl10-Malt1 signalosome controls TGF-β–activated kinase 1 (TAK1) activation and regulates BCR-induced NF-κB activation. In this study, we discovered that CARD19 interacted with TAK1 and inhibi
Autor:
David A. Proia, Iman El-Hariry, Stephan W. Morris, D. Ross Camidge, Richard C. Bates, Suqin He, Robert C. Doebele, Alice T. Shaw, John-Paul Jimenez, Christine M. Lovly, Liquan Xue, Qin Jiang, Chaohua Zhang, Manuel Sequeira, Donald L. Smith, Julie C. Friedland, Jaime Acquaviva, Jim Sang
PDF file - 251K, Chemical structures of ganetespib and crizotinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39dc5c22057378f8df93d617a21671ed
https://doi.org/10.1158/2159-8290.22530747.v1
https://doi.org/10.1158/2159-8290.22530747.v1
Autor:
David A. Proia, Iman El-Hariry, Stephan W. Morris, D. Ross Camidge, Richard C. Bates, Suqin He, Robert C. Doebele, Alice T. Shaw, John-Paul Jimenez, Christine M. Lovly, Liquan Xue, Qin Jiang, Chaohua Zhang, Manuel Sequeira, Donald L. Smith, Julie C. Friedland, Jaime Acquaviva, Jim Sang
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578dd9225ce88a47f3a995ae4f325559
https://doi.org/10.1158/2159-8290.22530735
https://doi.org/10.1158/2159-8290.22530735
Autor:
David A. Proia, Iman El-Hariry, Stephan W. Morris, D. Ross Camidge, Richard C. Bates, Suqin He, Robert C. Doebele, Alice T. Shaw, John-Paul Jimenez, Christine M. Lovly, Liquan Xue, Qin Jiang, Chaohua Zhang, Manuel Sequeira, Donald L. Smith, Julie C. Friedland, Jaime Acquaviva, Jim Sang
PDF file - 486K, The addition of ganetespib to crizotinib does not result in added toxicity in H3122 xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4161e6fafcee3d4054ca9ff03bb65629
https://doi.org/10.1158/2159-8290.22530741
https://doi.org/10.1158/2159-8290.22530741
Autor:
David A. Proia, Iman El-Hariry, Stephan W. Morris, D. Ross Camidge, Richard C. Bates, Suqin He, Robert C. Doebele, Alice T. Shaw, John-Paul Jimenez, Christine M. Lovly, Liquan Xue, Qin Jiang, Chaohua Zhang, Manuel Sequeira, Donald L. Smith, Julie C. Friedland, Jaime Acquaviva, Jim Sang
PDF file - 2538K, Crizotinib-resistant H3122 CR1 cells express an EMT phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5431491285747122d44be04550a18ddb
https://doi.org/10.1158/2159-8290.22530738
https://doi.org/10.1158/2159-8290.22530738
Autor:
Hiroko Masuda, Kenichi Harano, Sakiko Miura, Ying Wang, Yuko Hirota, Oi Harada, Mohit Kumar Jolly, Yuki Matsunaga, Bora Lim, Anita L. Wood, Napa Parinyanitikul, Hee Jin Lee, Gyungyub Gong, Jason T. George, Herbert Levine, Jangsoon Lee, Xiaoping Wang, Anthony Lucci, Arvind Rao, Brock L. Schweitzer, O. Rayne Lawrence, Robert S. Seitz, Stephan W. Morris, David R. Hout, Seigo Nakamura, Savitri Krishnamurthy, Naoto T. Ueno
Publikováno v:
JCO precision oncology. 6
PURPOSE Lehmann et al have identified four molecular subtypes of triple-negative breast cancer (TNBC)—basal-like (BL) 1, BL2, mesenchymal (M), and luminal androgen receptor—and an immunomodulatory (IM) gene expression signature modifier. Our grou
Autor:
Kamaleldin E. Elagib, Ashton Brock, Cara M. Clementelli, Goar Mosoyan, Lorrie L. Delehanty, Ranjit K. Sahu, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, Stephan W. Morris, Koji Eto, Chintan Jobaliya, Deborah L. French, Paul Gadue, Sandeep Singh, Xinrui Shi, Fujun Qin, Robert Cornelison, Hui Li, Camelia Iancu-Rubin, Adam N. Goldfarb
Publikováno v:
The Journal of clinical investigation. 132(19)
Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of hyperproliferation, limited morphogenesis, and low platelet production capacity. These properties contribute to clinical problems that include thrombocytopeni