Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stephan W Jahn"'
Autor:
Brigitte Pelzmann, Ahmed Hatab, Susanne Scheruebel, Sonja Langthaler, Theresa Rienmueller, Armin Sokolowski, Astrid Gorischek, Dieter Platzer, Klaus Zorn-Pauly, Stephan W. Jahn, Thomas Bauernhofer, Wolfgang Schreibmayer
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A search in the GDC Data Portal revealed 304 documented somatic mutations of the KCNJ3 gene in primary tumors (out of 10.202 cases). Most affected tumor types were carcinomas from uterus, skin and lung, while breast cancer exerted the lowest number o
Externí odkaz:
https://doaj.org/article/25e751d727e649c9b262bb838d06b3f1
Autor:
Jakob M. Riedl, Samantha O. Hasenleithner, Gudrun Pregartner, Lukas Scheipner, Florian Posch, Karin Groller, Karl Kashofer, Stephan W. Jahn, Thomas Bauernhofer, Martin Pichler, Herbert Stöger, Andrea Berghold, Gerald Hoefler, Michael R. Speicher, Ellen Heitzer, Armin Gerger
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for this purpose.
Externí odkaz:
https://doaj.org/article/6908822717ae4acb80b68f6cfaa4b07b
Autor:
Stephan W. Jahn, Philipp J. Jost
Publikováno v:
memo - Magazine of European Medical Oncology. 15:303-306
SummaryProfiling of malignancies with next-generation sequencing (NGS) is now routine in clinical practice. While many cases of approved targeted therapies are straightforward based on well-characterized alterations, applying large NGS multigene pane
Autor:
Gudrun Pregartner, Gerald Hoefler, Stephan W Jahn, Lukas Scheipner, Ellen Heitzer, Samantha O Hasenleithner, Herbert Stöger, Karin Groller, Florian Posch, Martin Pichler, Karl Kashofer, Thomas Bauernhofer, Andrea Berghold, Jakob M. Riedl, Armin Gerger, Michael R. Speicher
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for this purpose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6027a7848df2811d7284addc97fb666e
https://opus.bibliothek.uni-augsburg.de/opus4/files/101638/1758835920987658.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/101638/1758835920987658.pdf
Autor:
Christiane Klec, Erik Knutsen, Daniela Schwarzenbacher, Katharina Jonas, Barbara Pasculli, Ellen Heitzer, Beate Rinner, Katarina Krajina, Felix Prinz, Benjamin Gottschalk, Peter Ulz, Alexander Deutsch, Andreas Prokesch, Stephan W. Jahn, S. Mohammad Lellahi, Maria Perander, Raffaela Barbano, Wolfgang F. Graier, Paola Parrella, George Adrian Calin, Martin Pichler
The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in breast carcinogenesis are completely unknown. Here, we identified high ALYREF expression as a fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b8faecaa19eb0b3fc375c1bcbcb413
https://hdl.handle.net/10037/27596
https://hdl.handle.net/10037/27596
Autor:
Wolfgang Schreibmayer, Ruth Prassl, Stefanie Stanzer, Katja Ester, Sonja Langthaler, Nassim Ghaffari-Tabrizi-Wizsy, Simin Rezania, Andreas Prokesch, Helmut Ahammer, Dieter Platzer, Susanne Scheruebel, Brigitte Pelzmann, Klaus Zorn-Pauly, Gebhard Schratter, Trevor DeVaney, Thomas Bauernhofer, Kurt Schmidt, Astrid Gorischek, Stephan W Jahn
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Scientific Reports
Scientific Reports
Excessive expression of subunit 1 of GIRK1 in ER+ breast tumors is associated with reduced survival times and increased lymph node metastasis in patients. To investigate possible tumor-initiating properties, benign MCF10A and malign MCF7 mammary epit
Autor:
Florian Posch, Stephan W Jahn, Peter Regitnig, Hanno Gerritsmann, Christoph Suppan, Eva Valentina Klocker, Qing Zhou, Ellen Heitzer, Rupert Bartsch, Marija Balic, Ricarda Graf, Karl Kashofer, Nadia Dandachi, Angelika Terbuch, Philipp J. Jost, Joerg Lindenmann
Publikováno v:
Br J Cancer
Background The benefit of alpelisib in hormone-receptor-positive (HR+) metastatic breast cancer patients provided clinical evidence for the increasing importance of PIK3CA testing. We performed a comparison of liquid biopsy and tissue-based detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34630344238eab82bfd7b4225c5de38
https://europepmc.org/articles/PMC8810831/
https://europepmc.org/articles/PMC8810831/
Autor:
Felix Offner, Zerina Jasarevic, Michael Knauer, Christine Gruber-Rossipal, Andreas Bösl, Ruth Helfgott, Marija Balic, Farid Moinfar, Florian Fitzal, Oleksiy Tsybrovskyy, Stephan W Jahn
Publikováno v:
British Journal of Cancer
Inter-test concordance between the MammaPrint and the EndoPredict tests used to predict the risk of recurrence in breast cancer was evaluated in 94 oestrogen receptor-positive, HER2-negative breast cancers. We correlated histopathological data with c
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 3697, p 3697 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine
Digital pathology is on the verge of becoming a mainstream option for routine diagnostics. Faster whole slide image scanning has paved the way for this development, but implementation on a large scale is challenging on technical, logistical, and fina
Publikováno v:
Geburtshilfe und Frauenheilkunde.