Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stephan Struckmann"'
Autor:
Carsten Oliver Schmidt, Stephan Struckmann, Cornelia Enzenbach, Achim Reineke, Jürgen Stausberg, Stefan Damerow, Marianne Huebner, Börge Schmidt, Willi Sauerbrei, Adrian Richter
Publikováno v:
BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background No standards exist for the handling and reporting of data quality in health research. This work introduces a data quality framework for observational health research data collections with supporting software implementations to fac
Externí odkaz:
https://doaj.org/article/b76e6474393344feba5fb311f1a19a4f
Publikováno v:
Applied Sciences, Vol 12, Iss 9, p 4238 (2022)
Data quality assessments (DQA) are necessary to ensure valid research results. Despite the growing availability of tools of relevance for DQA in the R language, a systematic comparison of their functionalities is missing. Therefore, we review R packa
Externí odkaz:
https://doaj.org/article/4fdd8c08abf54d23a0f81beab3835957
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81784 (2013)
In silico approaches are increasingly considered to improve breast cancer treatment. One of these treatments, neoadjuvant TFAC chemotherapy, is used in cases where application of preoperative systemic therapy is indicated. Estimating response to trea
Externí odkaz:
https://doaj.org/article/be44f11962e742d6804d9dcb3e7e116b
Autor:
Carsten Oliver Schmidt, Stephan Struckmann, Maik Scholz, Janka Schössow, Dörte Radke, Adrian Richter, Achim Reineke, Elisa Kasbohm, Joany Mariño Coronado, Birgit Schauer, Kristin Henselin, Susanne Westphal, Darko Balke, Torsten Leddig, Henry Völzke, Jörg Henke
Publikováno v:
Caring is Sharing – Exploiting the Value in Data for Health and Innovation ISBN: 9781643683881
Conducting large-scale epidemiologic studies requires powerful software for electronic data capture, data management, data quality assessments, and participant management. There is also an increasing need to make studies and the data collected findab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be7ddf257a86b46779d211ec6ff67c0
https://doi.org/10.3233/shti230292
https://doi.org/10.3233/shti230292
Autor:
Anja U. Bräuer, Maria Vittoria Cubellis, Georg Fuellen, Jan Lukas, Anne-Katrin Giese, Arndt Rolfs, Mathias Ernst, Giuseppina Andreotti, Stephan Struckmann, Andreas Hermann, Linda Rebecca Haake, Anne-Marie Knospe, Claudia Cozma, Valentina Citro, Susanne Seemann, Chiara Cimmaruta, Dirk Koczan
Publikováno v:
Biochemical journal (Online) (2020). doi:10.1042/BCJ20190513
info:cnr-pdr/source/autori:Susanne Seemann ; Mathias Ernst ; Chiara Cimmaruta ; Stephan Struckmann ; Claudia Cozma ; Dirk Koczan ; Anne-Marie Knospe ; Linda R Haake ; Valentina Citro ; Anja U Bräuer ; Giuseppina Andreotti ; Maria V Cubellis ; Georg Fuellen ; Andreas Hermann ; Anne-Katrin Giese ; Arndt Rolfs ; Jan Lukas/titolo:Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypesin Fabry disease/doi:10.1042%2FBCJ20190513/rivista:Biochemical journal (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
The biochemical journal / Reviews 477(2), 359-380 (2020). doi:10.1042/BCJ20190513
Biochemical Journal
info:cnr-pdr/source/autori:Susanne Seemann ; Mathias Ernst ; Chiara Cimmaruta ; Stephan Struckmann ; Claudia Cozma ; Dirk Koczan ; Anne-Marie Knospe ; Linda R Haake ; Valentina Citro ; Anja U Bräuer ; Giuseppina Andreotti ; Maria V Cubellis ; Georg Fuellen ; Andreas Hermann ; Anne-Katrin Giese ; Arndt Rolfs ; Jan Lukas/titolo:Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypesin Fabry disease/doi:10.1042%2FBCJ20190513/rivista:Biochemical journal (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
The biochemical journal / Reviews 477(2), 359-380 (2020). doi:10.1042/BCJ20190513
Biochemical Journal
The lysosomal storage disorder Fabry disease is characterized by a deficiency of the lysosomal enzyme α-Galactosidase A. The observation that missense variants in the encoding GLA gene often lead to structural destabilization, endoplasmic reticulum
Autor:
Carsten Schmidt, Stephan Struckmann, Cornelia Enzenbach, Achim Reineke, Jürgen Stausberg, Stefan Damerow, Marianne Huebner, Börge Schmitt, Willi Sauerbrei, Adrian Richter
Background No standards exist for the handling and reporting of data quality in health research. This work introduces a data quality framework for observational health research data collections with supporting software implementations to facilitate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::823978ee1c9062642b296bc4730faab8
https://doi.org/10.21203/rs.3.rs-119457/v1
https://doi.org/10.21203/rs.3.rs-119457/v1
Autor:
Katharina A Sterenczak, Julia Beck, Israel Barrantes, Anselm Jünemann, Gregor Warsow, Stephan Struckmann, Steffen Möller, Robert Rejdak, Georg Fuellen, Oliver Stachs, Thomas Stahnke, Ekkehard Schütz, Beata Gajda-Deryło
Publikováno v:
Royal Society Open Science
To elucidate and to inhibit post-surgical fibrotic processes after trabeculectomy in glaucoma therapy, we measured gene expression in a fibrotic cell culture model, based on transforming growth factor TGF-β induction in primary human tenon fibroblas
Publikováno v:
Aging
Publikováno v:
Journal of Open Source Softwar
Autor:
Mohamed Hamed, Yvonne Gladbach, Steffen Möller, Sarah Fischer, Mathias Ernst, Stephan Struckmann, Alexander Storch, Georg Fuellen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
The volume of molecular observations on human diseases in public databases is continuously increasing at accelerating rates. A bottleneck is their computational integration into a coherent description, from which researchers may derive new well-found