Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Stephan Stremersch"'
Autor:
Laurens Raes, Melissa Pille, Aranit Harizaj, Glenn Goetgeluk, Jelter Van Hoeck, Stephan Stremersch, Juan C. Fraire, Toon Brans, Olivier Gerrit de Jong, Roel Maas-Bakker, Enrico Mastrobattista, Pieter Vader, Stefaan C. De Smedt, Bart Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 696-707 (2021)
The CRISPR-Cas9 technology represents a powerful tool for genome engineering in eukaryotic cells, advancing both fundamental research and therapeutic strategies. Despite the enormous potential of the technology, efficient and direct intracellular del
Externí odkaz:
https://doaj.org/article/d83a80530b204562bf8701e1aa7bfddd
Autor:
Laurens Raes, Stephan Stremersch, Juan C. Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, Xavier Saelens, Bart Vandekerckhove, Stefaan De Smedt, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Nano-Micro Letters, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Efficient and safe cell engineering by transfection of nucleic acids remains one of the long-standing hurdles for fundamental biomedical research and many new therapeutic applications, such as CAR T cell-based therapies. mRNA has recently ga
Externí odkaz:
https://doaj.org/article/543a96ad06524b4f9271212ffb59401e
Autor:
Sriram Balusu, Elien Van Wonterghem, Riet De Rycke, Koen Raemdonck, Stephan Stremersch, Kris Gevaert, Marjana Brkic, Delphine Demeestere, Valerie Vanhooren, An Hendrix, Claude Libert, Roosmarijn E Vandenbroucke
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 10, Pp 1162-1183 (2016)
Abstract Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced an increase in EVs and associated pro‐inflammatory miRNAs,
Externí odkaz:
https://doaj.org/article/6d64e554a98c44b7a2568b682bcc28e6
Autor:
Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan C. Fraire, Toon Brans, Ranhua Xiong, Stefaan De Smedt, Linos Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Crystals, Vol 9, Iss 8, p 411 (2019)
The modification of CD4+ T cells with exogenous nucleic acids or proteins is a critical step in several research and therapeutic applications, such as HIV studies and cancer immunotherapies. However, efficient cell transfections are not always easily
Externí odkaz:
https://doaj.org/article/5f79c192ee3943908590f8ae3310d25b
Autor:
Rita S Santos, George R Dakwar, Ranhua Xiong, Katrien Forier, Katrien Remaut, Stephan Stremersch, Nuno Guimarães, Sílvia Fontenete, Jesper Wengel, Marina Leite, Céu Figueiredo, Stefaan C De Smedt, Kevin Braeckmans, Nuno F Azevedo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H. pylori
Externí odkaz:
https://doaj.org/article/c2573389785b4b008350aa1ac492161f
Autor:
Juan C. Fraire, Ine Lentacker, Filip Van Hauwermeiren, Aranit Harizaj, Toon Brans, Stefaan C. De Smedt, Riet De Rycke, Kevin Braeckmans, Stephan Stremersch, Herlinde De Keersmaecker, Karolien Grauwen, Mohamed Lamkanfi
Publikováno v:
Nanoscale
Inflammasomes are multi-protein complexes that guard against cellular stress and microbial infections. Inflammasome activation studies frequently require delivery of pathogen-derived virulence factors into the cytosol of macrophages and other innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf608f2bb3d1b2ff22317e8c01017b3
https://doi.org/10.1039/d0nr05067a
https://doi.org/10.1039/d0nr05067a
Autor:
Gaëlle Houthaeve, Gerardo García-Díaz Barriga, Stephan Stremersch, Herlinde De Keersmaecker, Juan Fraire, Jo Vandesompele, Pieter Mestdagh, Stefaan De Smedt, Kevin Braeckmans, Winnok H. De Vos
Publikováno v:
CELLULAR AND MOLECULAR LIFE SCIENCES
Cellular and Molecular Life Sciences
Cellular and molecular life sciences
Cellular and Molecular Life Sciences
Cellular and molecular life sciences
Vapor nanobubble (VNB) photoporation is a physical method for intracellular delivery that has gained significant interest in the past decade. It has successfully been used to introduce molecular cargo of diverse nature into different cell types with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fa3e539ed963dce1c441c0d657c0e9
https://hdl.handle.net/1854/LU-8743612
https://hdl.handle.net/1854/LU-8743612
Autor:
Elke De Schutter, Jana Ramon, Benjamin Pfeuty, Caroline De Tender, Stephan Stremersch, Koen Raemdonck, Ken Op de Beeck, Wim Declercq, Franck B. Riquet, Kevin Braeckmans, Peter Vandenabeele
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2022, 79 (1), pp.19. ⟨10.1007/s00018-021-04078-0⟩
CELLULAR AND MOLECULAR LIFE SCIENCES
Cellular and molecular life sciences
Cellular and Molecular Life Sciences, 2022, 79 (1), pp.19. ⟨10.1007/s00018-021-04078-0⟩
CELLULAR AND MOLECULAR LIFE SCIENCES
Cellular and molecular life sciences
Secondary necrosis has long been perceived as an uncontrolled process resulting in total lysis of the apoptotic cell. Recently, it was shown that progression of apoptosis to secondary necrosis is regulated by Gasdermin E (GSDME), which requires activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f83354acaefc13ef0521b0dfb8f03c
https://hal.science/hal-04012801/file/schutter_cmls_22.pdf
https://hal.science/hal-04012801/file/schutter_cmls_22.pdf
Autor:
Jana Ramon, Wim Declercq, Stephan Stremersch, Benjamin Pfeuty, Caroline De Tender, Elke De Schutter, Franck B. Riquet, Peter Vandenabeele, Koen Raemdonck, Ken Op de Beeck, Kevin Braeckmans
Secondary necrosis has long been perceived as an uncontrolled process resulting in total lysis of the apoptotic cell. Recently, it was shown that progression of apoptosis to secondary necrosis is regulated by Gasdermin E (GSDME), which requires activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aaa482ea84af65f2e8958192639aa44
https://doi.org/10.21203/rs.3.rs-592826/v1
https://doi.org/10.21203/rs.3.rs-592826/v1
Autor:
Kevin Braeckmans, Riet De Rycke, Juan C. Fraire, Tinne Monteyne, Stephan Stremersch, Davinia Bouckaert, Pieter Wuytens, Thomas De Beer, Andre G. Skirtach, Koen Raemdonck, Stefaan C. De Smedt
Publikováno v:
ACS Applied Materials & Interfaces. 11:39424-39435
Exosome-like vesicles (ELVs) are nanovectors released by cells that are endowed with a variety of molecules, including proteins, nucleic acids, and chemicals that reflect the molecular signature of the producing cell. Given their presence in many bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7199048204bed355e4790b2a6b73aefb
https://doi.org/10.1021/acsami.9b11473
https://doi.org/10.1021/acsami.9b11473