Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephan Scheeff"'
Autor:
Xiaoding Jiang, Xu He, Jonathan Wong, Stephan Scheeff, Sam Chun-Kit Hau, Tak Hin Wong, Yao Qin, Chi Hang Fan, Bowen Ma, Ngai Lam Chung, Junzhe Huang, Jiajia Zhao, Yu Yan, Min Xiao, Xueqin Song, Tony K. C. Hui, Zhong Zuo, William Ka-Kei Wu, Ho Ko, Kim Hei-Man Chow, Billy Wai-Lung Ng
Publikováno v:
JACS Au, Vol 4, Iss 9, Pp 3537-3546 (2024)
Externí odkaz:
https://doaj.org/article/b2b61db2344b4ad188d3047fa5d873d2
Publikováno v:
eLife, Vol 12 (2023)
Understanding how to harden liquid condensates produced by influenza A virus could accelerate the development of novel antiviral drugs.
Externí odkaz:
https://doaj.org/article/d326c5dfa84040cebb2da88f76e5ae02
Autor:
Stephan Scheeff, Dirk Menche
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1085-1098 (2017)
V-ATPase has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with the archazolids, complex polyketide macrolides which present the most potent V-ATPase inhibitors known to date, rendering these
Externí odkaz:
https://doaj.org/article/b2365d805fa94adbb230430af9625a20
Autor:
Sebastian Bretzke, Stephan Scheeff, Felicitas Vollmeyer, Friederike Eberhagen, Frank Rominger, Dirk Menche
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1111-1121 (2016)
The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint
Externí odkaz:
https://doaj.org/article/b8364cffa4dd4e7faa24c3dc56cf341b
Autor:
Siyuan Guo, Kong Ching Wong, Stephan Scheeff, Zhuo He, Wesley Ting Kwok Chan, Kam-Hung Low, Pauline Chiu
Publikováno v:
The Journal of Organic Chemistry. 87:429-452
The copper-catalyzed reductive Ireland-Claisen rearrangement of propargylic acrylates led to 3,4-allenoic acids. The use of silanes or pinacolborane as stoichiometric reducing agents and triethylphosphite as a ligand facilitated the divergent and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcbdbfb4811fd76e0cedcaf93ca0200
https://doi.org/10.1021/acs.joc.1c02455
https://doi.org/10.1021/acs.joc.1c02455
Publikováno v:
The Journal of Organic Chemistry. 86:10190-10223
Full details on the design, development, and successful implementation of suitable synthetic strategies directed toward the total synthesis of iso-archazolids and archazologs are reported. Both a biomimetic and a multistep total synthesis of iso-arch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe63498352d74c04ff0303dc57e5c4c
https://doi.org/10.1021/acs.joc.1c00946
https://doi.org/10.1021/acs.joc.1c00946
Autor:
Helmut Wieczorek, Felix Tiburcy, Anna-Christina Schulz-Fincke, Meryem Köse, Johal Ruiz, Stephan Scheeff, Christa E. Müller, Dirk Menche, Michael Gütschow, Solenne Rivière, Aliaa Abdelrahman
Publikováno v:
Journal of medicinal chemistry. 63(4)
Vacuolar type ATPase (V-ATPase) has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with archazolids, complex polyketide macrolides, which present the most potent V-ATPase inhibitors known to da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5a6118fbe71b40ede0344def29dfc7
https://pubmed.ncbi.nlm.nih.gov/31990540
https://pubmed.ncbi.nlm.nih.gov/31990540
Autor:
Dirk Menche, Stephan Scheeff
Publikováno v:
Organic letters. 21(1)
A partial bioinspired as well as the total synthesis of archazolid F, a highly potent V-ATPase inhibitory, antiproliferative polyketide macrolide, is described. Key features of the synthetic routes include a highly stereoselective aldol condensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7c810ff99e1125cafa94c788732571
https://pubmed.ncbi.nlm.nih.gov/30548075
https://pubmed.ncbi.nlm.nih.gov/30548075
Autor:
Friederike Eberhagen, Frank Rominger, Stephan Scheeff, Felicitas Vollmeyer, Sebastian Bretzke, Dirk Menche
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1111-1121 (2016)
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1111-1121 (2016)
The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe621aa0492f76304021d152ba4e391
http://europepmc.org/articles/PMC4902044
http://europepmc.org/articles/PMC4902044
Autor:
Felicitas Vollmeyer, Frank Rominger, Sebastian Bretzke, Friederike Eberhagen, Stephan Scheeff, Dirk Menche
Publikováno v:
ChemInform. 47
The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3b50e5973f32bd422bd7d8262418dd
https://doi.org/10.1002/chin.201640212
https://doi.org/10.1002/chin.201640212