Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Stephan Reichl"'
Autor:
Leon Balters, Stephan Reichl
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
The cornea is the outermost layer of the eye and serves to protect the eye and enable vision by refracting light. The need for cornea organ donors remains high, and the demand for an artificial alternative continues to grow. 3D bioprinting is a promi
Externí odkaz:
https://doaj.org/article/9c629621da1242adbdd9d1bcfb1e3055
Autor:
Rebekka Schwab, Stephan Reichl
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 33, Iss 3, Pp 1-19 (2022)
Abstract Amniotic membrane (AM) is often applied as a substitute material during ocular surface reconstruction. However, since AM has several disadvantages, alternative materials must be considered for this application. Keratin films made from human
Externí odkaz:
https://doaj.org/article/349262f255654e6b8618495c17467ea3
Autor:
Eugen Viktor Koch, Sebastian Bendas, Kristina Nehlsen, Tobias May, Stephan Reichl, Andreas Dietzel
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2439 (2023)
The nasal mucosa, being accessible and highly vascularized, opens up new opportunities for the systemic administration of drugs. However, there are several protective functions like the mucociliary clearance, a physiological barrier which represents
Externí odkaz:
https://doaj.org/article/9bcd82d78acc4ff0b37d5c4ba74b7725
Autor:
Sebastian Bendas, Eugen Viktor Koch, Kristina Nehlsen, Tobias May, Andreas Dietzel, Stephan Reichl
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2245 (2023)
In recent years, there has been a significant increase in the registration of drugs for nasal application with systemic effects. Previous preclinical in vitro test systems for transmucosal drug absorption studies have mostly been based on primary cel
Externí odkaz:
https://doaj.org/article/c00efefd11cd410d9a90367d0375fbc9
Autor:
Stephan Reichl, Eric Mädl, Felix Riedlberger, Martin Piesch, Gábor Balázs, Michael Seidl, Manfred Scheer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Asymmetrically substituted phosphine ligands play a decisive role in catalysis, but their synthesis is rather challenging and often involves hazardous chemicals such as PCl3 or PH3. Here, the authors report the one-pot preparation of asymmetric phosp
Externí odkaz:
https://doaj.org/article/fc0054bb3c154684a05404a5a726a097
Autor:
Bo Tang, Sebastian Bendas, Victor Krajka, Tobias May, Anke Moritz, Iordania Constantinou, Stephan Reichl, Andreas Dietzel
Publikováno v:
Frontiers in Sensors, Vol 3 (2022)
Embedded porous membranes are a key element of various organ-on-chip systems. The widely used commercial polymer membranes impose limits with regard to chip integration and thinness. We report a microfluidic chip platform with the key element of a mo
Externí odkaz:
https://doaj.org/article/3540cf8365f74c20ab46d314546039ff
Autor:
Verena Ledwig, Stephan Reichl
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1688 (2023)
The blood–brain barrier (BBB) is the bottleneck in the development of new drugs to reach the brain. Due to the BBB, toxic substances cannot enter the brain, but promising drug candidates also pass the BBB poorly. Suitable in vitro BBB models are th
Externí odkaz:
https://doaj.org/article/090d2acea86f4e50a74f01f6b52cfe13
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1567 (2023)
This study aimed to develop valid in vitro models for preclinical evaluation of proliferative and anti-inflammatory effects of human allogeneic serum eye drops for dry eye disease (DED) treatment. A DED wound healing model was developed by analyzing
Externí odkaz:
https://doaj.org/article/0c0d24dd9f9440b0a008c9a9b2a564c5
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2128 (2022)
The relevance of the polymorphic form, particle size, and processing of mannitol for the mechanical properties of solid oral dosage forms was examined. Thus, particle and powder properties of spray granulated β D-mannitol, β D-mannitol, and δ D-ma
Externí odkaz:
https://doaj.org/article/0f1253628a284002a4b3708d56b7ae45
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1451 (2022)
One key application of organ-on-chip systems is the examination of drug transport and absorption through native cell barriers such the blood–brain barrier. To overcome previous hurdles related to the transferability of existing static cell cultivat
Externí odkaz:
https://doaj.org/article/14c894b61bc04564b02d5a6412d3ffbd