Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Stephan R. Holmer"'
Autor:
Andreas Jeron, Günter A.J. Riegger, Stefan Buchner, Kurt Debl, Matthias Lubnow, Stefan Barlage, Daniel P. Griese, Andreas Luchner, Frank Muders, Sabine Fredersdorf, Thomas Müller, Stephan R. Holmer
Publikováno v:
cclm. 48:875-881
Background: Whereas N-terminal pro-brain natriuretic peptide (NT-proBNP) is approved for risk stratification of patients with acute coronary syndromes (ACS), short-term temporal changes in NT-proBNP concentrations and the optimal time points for samp
Autor:
Peter W. Radke, Hans-Werner Hense, Henrike Liptau, Björn Mayer, Jeanette Erdmann, Andrea Bässler, Heribert Schunkert, Marcus Fischer, Lars C. Doehring, Anika Götz, Stephan R. Holmer, Zouhair Aherrahrou, Wolfgang Lieb, Christian Hengstenberg
Publikováno v:
Journal of Hypertension. 25:1731-1738
OBJECTIVES Coronary artery calcification (CAC) determined by electron beam computed tomography is a predictor of future cardiovascular events. This study investigates conditions affecting CAC severity in patients with coronary artery disease (CAD) un
Autor:
Andreas Jeron, A. Baessler, Christian Hengstenberg, Silke Wiedmann, Klaus Stark, Kamil Sedlacek, Marcus Fischer, Jeanette Erdmann, Katharina Neureuther, Heribert Schunkert, Wibke Hengstenberg, Stephan R. Holmer
Publikováno v:
Clinical Science. 113:213-218
Recently, the genetic variant Y402H in the CFH (complement factor H) gene was associated with an increased risk for MI (myocardial infarction) in a prospective Caucasian cohort. In another nested case-control study, however, the CFH -Y402H variant di
Autor:
Michael D. Harrison, Johanne Tremblay, Christian Glöckner, Jeff T. Williams, Karen Maresso, Ulrich Broeckel, Christian Hengstenberg, Ondrej Seda, Jeanette Erdmann, Howard J. Jacob, Heribert Schunkert, Gerd Schmitz, Bjoern Mayer, Daniel Gaudet, Lisa J. Martin, Stephan R. Holmer, Guenter Riegger, Pavel Hamet
Publikováno v:
Human Genetics. 122:95-102
High sensitivity C-reactive protein (hsCRP) is an independent risk factor for cardiovascular disease, such as stroke or coronary artery disease. Genetic factors influence significantly the inter-individual variability of hsCRP. The aim of this study
Autor:
Tanja Kaiser, Jörg Marienhagen, Andreas Luchner, Norbert Heinicke, Johann Schönberger, Mark Segmüller, Christoph Eilles, Stephan R. Holmer, Günter A.J. Riegger, Bernhard Benesch, Kurt Debl
Publikováno v:
Clinical Research in Cardiology. 95:650-656
In the diagnosis of coronary artery disease (CAD) with Dobutamine Stress Echocardiography (DSE), regional wall motion abnormalities (RWMA) are assumed to indicate a perfusion deficit.For a more particular examination of RWMAs, we compared simultaneou
Autor:
Björn Mayer, Anika Götz, Jan Stritzke, Jochen Graf, Stephan R. Holmer, Marcus Fischer, Wolfgang Lieb, Christian Hengstenberg, Angela Döring, Heribert Schunkert, Hannelore Löwel, Jeanette Erdmann, Inke R. König
Publikováno v:
J. Mol. Med. 84, 88-96 (2006)
Angiotensin-converting enzyme (ACE) activity is considered to be of major importance for the conversion of angiotensin (Ang) I to Ang II. Recently, a second ACE, named ACE2, has been identified. Experimental data provide evidence that ACE2 might be i
Autor:
Wolfgang Lieb, Annett Thiemig, Angela Doering, Stephan R. Holmer, Zouhair Aherrahrou, Inke R. König, Anika Götz, Heribert Schunkert, Hans-Werner Hense, Bjoern Mayer, Hannelore Loewel, Jeanette Erdmann, Christian Hengstenberg
Publikováno v:
Hypertension 46, 766-771 (2005)
Genetic variants of the arachidonic acid monooxygenase CYP4A11 result in decreased synthesis of 20-hydroxyeicostatetraenoic acid and experimental hypertension. Moreover, in humans, the T8590C polymorphism of CYP4A11 displayed association with arteria
Autor:
Günter A.J. Riegger, Christian Hengstenberg, Heribert Schunkert, Hannelore Löwel, Andreas Luchner, Stephan R. Holmer
Publikováno v:
Hypertension. 46:118-123
Brain natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) are markers of heart failure. Although renal dysfunction may increase plasma concentrations, the magnitude of this effect has not been assessed in a head-to-head comparison between th
Autor:
Stephan R. Holmer, Rotraud Meyringer, Ulf Müller-Ladner, Renate Oberhoffer, Jürgen Schölmerich
Publikováno v:
Medizinische Klinik. 100:279-283
Eine 17-jahrige Patientin stellte sich mit epigastrischen Schmerzen mit Ausstrahlung in Thorax und Hals in der Notaufnahme vor. Bei der Patientin war ein langjahriger systemischer Lupus erythematodes (SLE) mit vorwiegender Nierenbeteiligung bekannt.
Autor:
Marcus Fischer, Heribert Schunkert, Björn Mayer, S. Mell, V. Huf, Stephan R. Holmer, G. Riegger, A. Baessler, Christian Hengstenberg
Publikováno v:
International Journal of Cardiology. 101:293-298
The majority of patients with myocardial infarction (MI) and hypercholesterolaemia does not achieve guideline recommended low-density lipoprotein cholesterol (LDL) levels. Suboptimal dosages of statins explain this dilemma in most patients.We evaluat