Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Stephan N. Wagner"'
Autor:
Franziska Werner, Christine Wagner, Martin Simon, Katharina Glatz, Kirsten D. Mertz, Heinz Läubli, Johannes Griss, Stephan N. Wagner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
There is increasing evidence that tertiary lymphoid structures (TLS) control not only local adaptive B cell responses at melanoma tumor sites but also the cellular composition and function of other immune cells. In human melanoma, however, a comprehe
Externí odkaz:
https://doaj.org/article/7e84184c7d884add8874db79bcde43b3
Autor:
Minyi Chen, Franziska Werner, Christine Wagner, Martin Simon, Erika Richtig, Kirsten D. Mertz, Johannes Griss, Stephan N. Wagner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: The role of tumor-associated B cells in human cancer is only starting to emerge. B cells typically undergo a series of developmental changes in phenotype and function, however, data on the composition of the B cell population in human mel
Externí odkaz:
https://doaj.org/article/14be7fcc40fb4410b7d16c6d1db3fe8c
Autor:
Johannes Griss, Wolfgang Bauer, Christine Wagner, Martin Simon, Minyi Chen, Katharina Grabmeier-Pfistershammer, Margarita Maurer-Granofszky, Florian Roka, Thomas Penz, Christoph Bock, Gao Zhang, Meenhard Herlyn, Katharina Glatz, Heinz Läubli, Kirsten D. Mertz, Peter Petzelbauer, Thomas Wiesner, Markus Hartl, Winfried F. Pickl, Rajasekharan Somasundaram, Peter Steinberger, Stephan N. Wagner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The regulation of tumor inflammation is incompletely understood and the role of B cells is unclear. Here, the authors show that a specific subtype of B cells is induced in melanoma and required to recruit T lymphocytes and elicit inflammation.
Externí odkaz:
https://doaj.org/article/bb7a13c9ab124182a8b518e472ddcec1
Autor:
Franziska Werner, Christine Wagner, Martin Simon, Katharina Glatz, Kirsten D. Mertz, Heinz Läubli, Erika Richtig, Johannes Griss, Stephan N. Wagner
Publikováno v:
Diagnostics, Vol 11, Iss 7, p 1238 (2021)
Activated antigen-experienced B cells play an unexpected complex role in anti-tumor immunity in human melanoma patients. However, correlative studies between B cell infiltration and tumor progression are limited by the lack of distinction between fun
Externí odkaz:
https://doaj.org/article/9da3117e55264d839670984e3cc68fe8
Autor:
Rajasekharan Somasundaram, Gao Zhang, Mizuho Fukunaga-Kalabis, Michela Perego, Clemens Krepler, Xiaowei Xu, Christine Wagner, Denitsa Hristova, Jie Zhang, Tian Tian, Zhi Wei, Qin Liu, Kanika Garg, Johannes Griss, Rufus Hards, Margarita Maurer, Christine Hafner, Marius Mayerhöfer, Georgios Karanikas, Ahmad Jalili, Verena Bauer-Pohl, Felix Weihsengruber, Klemens Rappersberger, Josef Koller, Roland Lang, Courtney Hudgens, Guo Chen, Michael Tetzlaff, Lawrence Wu, Dennie Tompers Frederick, Richard A. Scolyer, Georgina V. Long, Manashree Damle, Courtney Ellingsworth, Leon Grinman, Harry Choi, Brian J. Gavin, Margaret Dunagin, Arjun Raj, Nathalie Scholler, Laura Gross, Marilda Beqiri, Keiryn Bennett, Ian Watson, Helmut Schaider, Michael A. Davies, Jennifer Wargo, Brian J. Czerniecki, Lynn Schuchter, Dorothee Herlyn, Keith Flaherty, Meenhard Herlyn, Stephan N. Wagner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Resistance to BRAFV600E inhibitors often occurs in melanoma patients. Here, the authors describe a potential mechanism of acquired drug resistance mediated by tumor-associated B cells-derived IGF-1.
Externí odkaz:
https://doaj.org/article/bdec5a8059084d31b97839ef9a5cc86d
Autor:
Katherine M. Aird, Gao Zhang, Hua Li, Zhigang Tu, Benjamin G. Bitler, Azat Garipov, Hong Wu, Zhi Wei, Stephan N. Wagner, Meenhard Herlyn, Rugang Zhang
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1252-1265 (2013)
Oncogene-induced senescence is characterized by a stable cell growth arrest, thus providing a tumor suppression mechanism. However, the underlying mechanisms for this phenomenon remain unknown. Here, we show that a decrease in deoxyribonucleotide tri
Externí odkaz:
https://doaj.org/article/c51fb2351544496e98a9bfbe85388849
Autor:
Ahmad Jalili, Kirsten D. Mertz, Julia Romanov, Christine Wagner, Frank Kalthoff, Anton Stuetz, Gaurav Pathria, Melanie Gschaider, Georg Stingl, Stephan N. Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/0de567f441f44ff6a4e5b3c0d1e53cb4
Autor:
Agnes Forsthuber, Ana Korosec, Tina Jacob, Bertram Aschenbrenner, Karl Annusver, Sophie Frech, Kim Purkhauser, Natalia Krajic, Katharina Lipp, Franziska Werner, Vy Nguyen, Johannes Griss, Wolfgang Bauer, Ana Soler Cardona, Benedikt Weber, Wolfgang Weninger, Bernhard Gesslbauer, Clement Staud, Jakob Nedomansky, Christine Radtke, Stephan N. Wagner, Peter Petzelbauer, Maria Kasper, Beate M. Lichtenberger
Cancer-associated fibroblasts (CAFs) play a key role in cancer progression and treatment outcome. Here, we elucidate the yet unresolved intra-tumoral CAF variety in three skin cancer types at molecular and spatial single-cell resolution in a large co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e3d6a704b566a37a9d53a8ed31a69cf
https://doi.org/10.1101/2023.05.03.539213
https://doi.org/10.1101/2023.05.03.539213
Autor:
Richard O. Hynes, Jill P. Mesirov, Sridhar Ramaswamy, Stephan N. Wagner, Jean-Philippe Brunet, Ken Ross, Aravind Subramanian, Yujin Hoshida, Steven S. Shen, Lei Xu
Supplementary Table S4 from Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19646f72f3217426c431881ea15242c8
https://doi.org/10.1158/1541-7786.22520742
https://doi.org/10.1158/1541-7786.22520742
Autor:
Richard O. Hynes, Jill P. Mesirov, Sridhar Ramaswamy, Stephan N. Wagner, Jean-Philippe Brunet, Ken Ross, Aravind Subramanian, Yujin Hoshida, Steven S. Shen, Lei Xu
Supplementary Figures S1-S2 from Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44f0ce2658cc9ad41e42db2ad0bd948
https://doi.org/10.1158/1541-7786.22520754
https://doi.org/10.1158/1541-7786.22520754