Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephan Meding"'
Autor:
Alice Ly, Axel Walch, Philippe Schmitt-Kopplin, Michael Witting, Marius Ueffing, Stephan Meding, Michaela Aichler, Stefanie M. Hauck, Na Sun
Publikováno v:
PROTEOMICS. 14:913-923
MS imaging (MSI) is a valuable tool for diagnostics and systems biology studies, being a highly sensitive, label-free technique capable of providing comprehensive spatial distribution of different classes of biomolecules. The application of MSI to th
Autor:
Marius Ueffing, Cédrik Schöne, Rupert Langer, Stefanie M. Hauck, Stefan Maier, Benjamin Balluff, Ludwig Hierber, Axel Walch, Stephan Meding, Marcus Feith, Michaela Aichler, Manfred Schmitt, Bernhard Kuster, Sandra Rauser, H. Braselmann, Horst Zitzelsberger, Heinz Höfler, Mareike Elsner, Michaela Aubele, Natalie Ludyga, Verena Zangen, Hans Zischka, Annette Feuchtinger
Publikováno v:
The Journal of Pathology. 230:410-419
Chemotherapeutic drugs kill cancer cells, but it is unclear why this happens in responding patients but not in non-responders. Proteomic profiles of patients with oesophageal adenocarcinoma may be helpful in predicting response and selecting more eff
Autor:
James S. Eddes, Peter Hoffmann, Shaun R. McColl, Stephan Meding, Martin K. Oehler, Ove J. R. Gustafsson
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:655-670
Ove J. R. Gustafsson, James S. Eddes, Stephan Meding, Shaun R. McColl, Martin K. Oehler and Peter Hoffmann
Autor:
Hakan Sarioglu, Axel Walch, Sandra Rauser, Bernhard Kuster, Benjamin Balluff, Mareike Elsner, Gerhard Jung, Michaela Aichler, Cédrik Schöne, Heinz Höfler, Horst Zitzelsberger, Giuseppina Maccarrone, Stephan Meding, Marcus Feith, Uta Jütting, Stefan Maier, Marius Ueffing, Rupert Langer, Martin Nipp, Annette Feuchtinger
Publikováno v:
Journal of Proteomics. 75:4693-4704
To characterize proteomic changes found in Barrett's adenocarcinoma and its premalignant stages, the proteomic profiles of histologically defined precursor and invasive carcinoma lesions were analyzed by MALDI imaging MS. For a primary proteomic scre
Autor:
Stephan Meding, Helmut Friess, Heinz Höfler, Axel Walch, Stefanie M. Hauck, Marius Ueffing, Rupert Langer, Alexander Schäfer, Sandra Rauser, Robert D. Rosenberg, Cédrik Schöne, Mareike Elsner, Matthias Maak, Benjamin Balluff, Ulrich Nitsche
Publikováno v:
The Journal of Pathology. 228:459-470
Regional lymph node metastasis negatively affects prognosis in colon cancer patients. The molecular processes leading to regional lymph node metastasis are only partially understood and proteomic markers for metastasis are still scarce. Therefore, a
Autor:
Axel Walch, Benjamin Balluff, Robert D. Rosenberg, Rupert Langer, Helmut Friess, Cédrik Schöne, Matthias Maak, Heinz Höfler, Matthias P. Ebert, Stephan Meding, Marcus Feith, Ulrich Nitsche, Martin Nipp, Mareike Elsner, Sandra Rauser, Horst Zitzelsberger
Publikováno v:
Journal of Proteome Research. 11:1996-2003
In clinical diagnostics, it is of outmost importance to correctly identify the source of a metastatic tumor, especially if no apparent primary tumor is present. Tissue-based proteomics might allow correct tumor classification. As a result, we perform
Autor:
Matthias P.A. Ebert, Andreas Kowarsch, Roland M. Schmid, Marcus Feith, Heinz Höfler, Sandra Rauser, Christoph Schuhmacher, Christoph Röcken, Mareike Elsner, Stephan Meding, Benjamin Balluff, Axel Walch, Ken Herrmann
Publikováno v:
Journal of Proteome Research. 9:6317-6322
HER2-testing in breast and gastric cancers is mandatory for the treatment with trastuzumab. We hypothesized that imaging mass spectrometry (IMS) of breast cancers may be useful for generating a classifier that may determine HER2-status in other cance
Autor:
Bilge Ergin, K. Becker, Axel Walch, Daniela Berg, Claudia Wolff, Katharina Malinowsky, Stephan Meding, Heinz Höfler
Publikováno v:
Der Pathologe. 31:263-267
Tissue samples have been routinely used for decades to distinguish healthy from diseased tissue in histopathological characterization. While nucleic acid-based methodologies have been successfully in use for many years, protein-based techniques, in c
Autor:
Stefanie M. Hauck, Michael Becker, Stephan Meding, Michaela Aichler, Detlev Suckau, Axel Walch, Janine Rattke, Marius Ueffing, Alice Ly, Cédrik Schöne
Publikováno v:
Histochemistry and cell biology. 143(5)
Matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) is emerging as a powerful tool for the analysis of molecular distributions in biological samples in situ. When compared to classical histology, the major benefit of th
Publikováno v:
Ann. Appl. Stat. 9, no. 4 (2015), 1973-1996
Imaging mass spectrometry (IMS) has transformed proteomics by providing an avenue for collecting spatially distributed molecular data. Mass spectrometry data acquired with matrix assisted laser desorption ionization (MALDI) IMS consist of tens of tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5905073bc01112d4c0272961dbded1
http://arxiv.org/abs/1410.1630
http://arxiv.org/abs/1410.1630