Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Stephan Mauersberger"'
Publikováno v:
Journal of Biotechnology. 339:42-52
New Yarrowia lipolytica strains for the co-expression of steroidogenic mammalian proteins were obtained in this study. For this purpose, a two-step approach for constructing recombinant strains that permits the simple introduction of several expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9939649933b48a0d6af697e734abeccc
https://doi.org/10.1016/j.jbiotec.2021.07.012
https://doi.org/10.1016/j.jbiotec.2021.07.012
Autor:
Dominique Böttcher, Uwe T. Bornscheuer, Kathleen Balke, Lisa K. Morlock, Sascha Grobe, Stephan Mauersberger
Publikováno v:
ChemBioChem. 19:1954-1958
The CYP171 enzyme is known to catalyse a key step in the steroidogenesis of mammals. The substrates progesterone and pregnenolone are first hydroxylated at the C17 position, and this is followed by cleavage of the C17-C20 bond to yield important prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b9a2cb891f2c482aa408cdd967b04c
https://doi.org/10.1002/cbic.201800371
https://doi.org/10.1002/cbic.201800371
Autor:
Andreas Aurich, Jörg Hofmann, Robert Oltrogge, Mike Wecks, Roger Gläser, Laura Blömer, Stephan Mauersberger, Roland A. Müller, Dieter Sicker, Athanassios Giannis
Publikováno v:
Organic Process Research & Development. 23:1105-1105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a6e086f0f5afd32faa387a5c58a36c8
https://doi.org/10.1021/acs.oprd.9b00097
https://doi.org/10.1021/acs.oprd.9b00097
Publikováno v:
Applied Microbiology and Biotechnology. 98:2003-2013
To establish and develop a biotechnological process of α-ketoglutaric acid (KGA) production by Yarrowia lipolytica, it is necessary to increase the KGA productivity and to reduce the amounts of by-products, e.g. pyruvic acid (PA) as major by-product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b5396e2abb427826cf9aa0144bff11
https://doi.org/10.1007/s00253-013-5369-9
https://doi.org/10.1007/s00253-013-5369-9
Autor:
I.P. Edimecheva, Vladimir M. Shkumatov, Hanna V. Hlushko, Stephan Mauersberger, N. S. Frolova, Y. V. Faletrov, E. V. Rudaya
Publikováno v:
FEBS Journal. 280:3109-3119
The fluorescent probes Nile Red (nonsteroidal dye) and 25-{N-[(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-methyl]amino}-27-norcholesterol (25-NBD-cholesterol) (a cholesterol analog) were evaluated as novel substrates for steroid-converting oxidoreductases. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed10f1c293a6d10eeffb26c75d789a7
https://doi.org/10.1111/febs.12265
https://doi.org/10.1111/febs.12265
Publikováno v:
Applied Microbiology and Biotechnology. 95:905-917
The yeast Yarrowia lipolytica secretes high amounts of various organic acids, like citric, isocitric, pyruvic (PA), and α-ketoglutaric (KGA) acids, triggered by growth limitation and excess of carbon source. This is leading to an increased interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229112cec12f46a9a8f161d78b506453
https://doi.org/10.1007/s00253-012-4085-1
https://doi.org/10.1007/s00253-012-4085-1
Autor:
Stephan Mauersberger, Ya. V. Faletrov, Valentin N. Luzikov, I. E. Kovaleva, Vladimir M. Shkumatov, L.A. Novikova
Publikováno v:
Biochemistry (Moscow). 74:1482-1504
(3/4) This review summarizes data about structural and functional organization of steroidogenic P450-dependent enzymatic systems. Problems of catalysis of steroid substrate transformation, special features of mitochondrial type P450scc topogenesis, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5daad9acdb72679971e8e00bd1592892
https://doi.org/10.1134/s0006297909130057
https://doi.org/10.1134/s0006297909130057
Publikováno v:
Applied Microbiology and Biotechnology. 81:1087-1096
The yeast Yarrowia lipolytica secretes high amounts of various organic acids, like citric acid (CA) and isocitric acid (ICA) under an excess of carbon source and several conditions of growth limitation. Depending on the carbon source used, Y. lipolyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688158b70106841d42a0ca33c0eae0ec
https://doi.org/10.1007/s00253-008-1725-6
https://doi.org/10.1007/s00253-008-1725-6
Publikováno v:
Applied Microbiology and Biotechnology. 77:861-869
The yeast Yarrowia lipolytica secretes high amounts of various organic acids, like citric (CA) and isocitric (ICA) acids, triggered by growth limitation caused by different factors and an excess of carbon source. Depending on the carbon source used,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bec81eee877329264fc52a8e340445
https://doi.org/10.1007/s00253-007-1205-4
https://doi.org/10.1007/s00253-007-1205-4
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 1:87-94
Using recombinant microorganisms S. cerevisiae GRF18/YEp 5117α, expressing bovine adrenocortical cytochrome P450cl7, we have studied the effect of various modifiers of steroid biosynthesis on the relationship between reactions of the 17α-hydroxylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b434a31b61c1da986782e5e5d4817d9
https://doi.org/10.1134/s1990750807010131
https://doi.org/10.1134/s1990750807010131