Zobrazeno 1 - 10 of 173 pro vyhledávání: '"Stephan M. Ensminger"'
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Akademický článek
AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome
Autor: Rawa Arif, Marcin Zaradzki, Anca Remes, Philipp Seppelt, Reiner Kunze, Hannes Schröder, Simon Schwill, Stephan M. Ensminger, Peter N. Robinson, Matthias Karck, Oliver J. Müller, Markus Hecker, Andreas H. Wagner, Klaus Kallenbach
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 69-79 (2017)
Marfan syndrome is characterized by high expression of matrix metalloproteinases (MMPs) in aortic smooth muscle cells (AoSMCs) associated with medial elastolysis and aortic root aneurysm. We aimed to reduce aortic elastolysis through decrease of MMP
Externí odkaz: https://doaj.org/article/d149b02da641496bb88b5064360f8425
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2
Akademický článek
Platelets and Immune Responses During Thromboinflammation
Autor: Matthias Mezger, Henry Nording, Reinhard Sauter, Tobias Graf, Christian Heim, Nikolas von Bubnoff, Stephan M. Ensminger, Harald F. Langer
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Besides mediating hemostatic functions, platelets are increasingly recognized as important players of inflammation. Data from experiments in mice and men revealed various intersection points between thrombosis, hemostasis, and inflammation, which are
Externí odkaz: https://doaj.org/article/cedb15f843bd4a4395ed325bbe05c4be
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3
Akademický článek
Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts
Autor: Annika Gocht, Bernd Spriewald, MD, DPhil, Jörg H.W. Distler, MD, Martina Ramsperger-Gleixner, PhD, Stephan M. Ensminger, MD, DPhil, Michael Weyand, MD, Christian Heim, MD
Publikováno v: Transplantation Direct, Vol 4, Iss 7, p e367 (2018)
Background. Nintedanib is a small molecule tyrosine kinase inhibitor that blocks the action of the platelet-derived growth factor receptor (PDGFR), the vascular endothelial growth factor receptor (VEGFR) and the fibroblast growth factor receptor. All
Externí odkaz: https://doaj.org/article/9aa96a05d4544b5d8413279447b95f9a
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4
Direct Impact of Human Platelets on the Development of Transplant Arteriosclerosis
Autor: Susann Görner, Stephan M. Ensminger, Michael Weyand, Benjamin von Silva-Tarouca, Martina Ramsperger-Gleixner, A. Kuckhahn, Benno Weigmann, Robert Zimmermann, Christian Heim
Publikováno v: Transplantation. 106:1180-1192
Background Platelets play an important role in the pathogenesis of inflammatory and proliferative vascular changes. The aim of this study was to investigate whether human platelets are able to induce transplant arteriosclerosis in a humanized C57/Bl6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a400f8dcbef3dd3c6cf4c4a5eabd767
https://doi.org/10.1097/tp.0000000000003935
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9
Ethical considerations regarding heart and lung transplantation and mechanical circulatory support during the COVID-19 pandemic: an ISHLT COVID-19 Task Force statement
Autor: Luciano Potena, Raymond L. Benza, Andrew M. Courtwright, M. Shullo, Marta Farrero, Jeffrey J. Teuteberg, Saima Aslam, Stuart C. Sweet, Stephan M. Ensminger, Mandeep R. Mehra, Lianne G. Singer, Are Martin Holm
Publikováno v: The Journal of Heart and Lung Transplantation
To understand the challenges for thoracic transplantation and mechanical circulatory support during the current coronavirus disease 2019 pandemic, we propose separating the effects of the pandemic into 5 distinct stages from a healthcare system persp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b93a26756702c905dd3fa68d7fa72a
https://doi.org/10.1016/j.healun.2020.04.019
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