Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stephan K. Miller"'
Autor:
Graham K. Farrington, Jessica E. Friedman, Joshua C. Yoburn, Alexey Lugovskoy, William Michael Flanagan, Stephan K. Miller, Brian C. Cunningham, Amy D. Fung, Adrian Whitty, Molly M. He, Jun Wang, Annemarie Stroustrup Smith, Mark T. Cancilla, John Eldredge, Leslie A. Cruz, Johan D. Oslob, Teresa G. Cachero, Andrew C. Braisted, Eric S. Day, Ingrid C. Choong
Publikováno v:
Science. 310:1022-1025
We have identified a small-molecule inhibitor of tumor necrosis factor α (TNF-α) that promotes subunit disassembly of this trimeric cytokine family member. The compound inhibits TNF-α activity in biochemical and cell-based assays with median inhib
Autor:
Molly M, He, Annemarie Stroustrup, Smith, Johan D, Oslob, William M, Flanagan, Andrew C, Braisted, Adrian, Whitty, Mark T, Cancilla, Jun, Wang, Alexey A, Lugovskoy, Josh C, Yoburn, Amy D, Fung, Graham, Farrington, John K, Eldredge, Eric S, Day, Leslie A, Cruz, Teresa G, Cachero, Stephan K, Miller, Jessica E, Friedman, Ingrid C, Choong, Brian C, Cunningham
Publikováno v:
Science (New York, N.Y.). 310(5750)
We have identified a small-molecule inhibitor of tumor necrosis factor alpha (TNF-alpha) that promotes subunit disassembly of this trimeric cytokine family member. The compound inhibits TNF-alpha activity in biochemical and cell-based assays with med