Výsledky vyhledávání - "Stephan Imreh"

The interferon-α responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma

Autor: Xiaoling Zhou, Stephan Imreh, George Klein, Nicholas C. Popescu

Publikováno v: Cancer Genetics and Cytogenetics. 177:6-15

Multiple regions on the chromosome arm 3p are frequently affected by loss of heterozygosity in human cancers. A candidate tumor suppressor gene is TMEM7 , at 3p21.3, which encodes a transmembrane protein. TMEM7 is expressed specifically in the liver,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59811fc478503ab7bbe791de10109bfb
https://doi.org/10.1016/j.cancergencyto.2007.04.007

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Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'

Autor: H. Kansoul, Stephan Imreh, M. Kost-Alimova, Hajnalka Kiss, George Klein, Eva Darai

Publikováno v: Genomics. 86:1-12

We have previously found with the microcell hybrid-based “elimination test” that human chromosome 3 transferred into murine or human tumor cells regularly lost certain 3p regions during tumor growth in SCID mice. The most common eliminated region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569b4ace4450784643c5a12d48a7d5d8
https://doi.org/10.1016/j.ygeno.2005.04.003

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A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3

Autor: Stephan Imreh, M. Kost-Alimova, Ingegerd Fransson, Ying Yang, Hajnalka Kiss, Jan P. Dumanski, Darek Kedra, George Klein, Csaba Kiss, Kevin O'Brien

Publikováno v: Human Genetics. 105:552-559

Chromosomal deletions on 3p have been described in a large number of human tumors, suggesting the presence of a tumor suppressor gene(s). Using an experimental system, called the elimination test, we previously identified a 1 Mb segment, the common e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4816f5b9a9d66fb7559430430a8cd6
https://doi.org/10.1007/s004399900188

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[Untitled]

Autor: Carl Perez, Judit Keresö, Erika Csonka, Gyula Hadlaczky, Stephan Imreh, Håkan Telenius, Anna Szeles, Jan I. Drayer, Tünde Praznovszky, Alexisann Maxwell

Publikováno v: Chromosome Research. 7:3-7

A 60-Mb murine chromosome consisting of murine pericentric satellite DNA and two bands of integrated marker and reporter genes has been generated de novo in a rodent/human hybrid cell line (mM2C1). This prototype mammalian artificial chromosome platf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e107bdf0f6338691523137c278ed068
https://doi.org/10.1023/a:1009215026001

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Differential elimination of 3p and retention of 3q segments in human/mouse microcell hybrids during tumor growth

Autor: Hajnalka Kiss, George Klein, Stephan Imreh, Irina Kholodnyuk, Maria Kost-Alimova, Karen Foster, Ying Yang, Yie Liu, Eric J. Stanbridge, Eugene R. Zabarovsky, Anna Szeles

Publikováno v: Genes, Chromosomes and Cancer. 20:224-233

We have previously found that human chromosome 3 was fragmented in the course of in vivo tumor growth of monochromosomal human/mouse (A9 fibrosarcoma parent) microcell hybrids in SCID mice. Marker analysis of tumor cell lines has identified a regular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a0a0f1b6e0705c44b8ec90e4d215a5b
https://doi.org/10.1002/(sici)1098-2264(199711)20:3<224::aid-gcc2>3.0.co

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A 3p21.3 region is preferentially eliminated from human chromosome 3/mouse microcell hybrids during tumor growth in SCID mice

Autor: Stephan Imreh, Irina Kholodnyuk, M. Kost-Alimova, Eric J. Stanbridge, Anna Szeles, Rinat Gizatulin, Vladimir I. Kashuba, Eugene R. Zabarovsky, George Klein

Publikováno v: Genes, Chromosomes and Cancer. 18:200-211

We have previously shown that four markers spanning the 3p24-p21.3 region, THRB, AP20R, D3S1029, and D3S32, were regularly eliminated from three human chromosome 3 (chr3)/mouse microcell hybrids (MCHs) during tumor growth in SCID mice. In an attempt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7978a7810b71895f30d2ce4ce15b0de4
https://doi.org/10.1002/(sici)1098-2264(199703)18:3<200::aid-gcc6>3.0.co

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Spontaneous development of plasmacytomas in a selected subline of BALB/cJ mice

Autor: Francis Wiener, Stephan Imreh, George Klein, Santiago Silva, M. Babonits, Yongzhi Wang

Publikováno v: European Journal of Cancer. 33:479-485

Sixty per cent of BALB/cAnPt mice injected intraperitoneally (i.p.) with tetramethylpentadecane (pristane) develop plasmacytomas (PCs), whereas less than 10% of BALB/cJ develop such tumours. Most other mouse strains are completely resistant. Resistan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d024b518be97cbb103970c06881940a
https://doi.org/10.1016/s0959-8049(97)89025-9

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