Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stephan Hellwig"'
Autor:
Bart W Faber, Stephan Hellwig, Sophie Houard, Nicolas Havelange, Jürgen Drossard, Hubert Mertens, Alexander Croon, Robin Kastilan, Richard Byrne, Nicole van der Werff, Marjolein van der Eijk, Alan W Thomas, Clemens H M Kocken, Edmond J Remarque
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading asexual blood stage vaccine candidate for malaria. In preparation for clinical trials, three Diversity Covering (DiCo) PfAMA1 ectodomain proteins, designed to overcome the intrinsi
Externí odkaz:
https://doaj.org/article/46cb131ada9e43298252bc652224aff9
Autor:
Andreas Reimann, Holger Spiegel, Alexander Boes, Nadja Voepel, Rainer Fischer, Johannes F. Buyel, Robin Kastilan, Stephan Hellwig, Ivana Chudobová
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Pichia pastoris is a simple and powerful expression platform that has the ability to produce a wide variety of recombinant proteins, ranging from simple peptides to complex membrane proteins. A well-established fermentation strategy is available comp
Autor:
Adelheid Degelmann, Cornelis P. Hollenberg, Sebastian Kleebank, Michael Piontek, Jens Klabunde, Stephan Hellwig
Publikováno v:
Fems Yeast Research
The type I membrane protein calnexin is a conserved key component of the quality control mechanism in the endoplasmic reticulum. It functions as a molecular chaperone that monitors the folding state of nascent polypeptides entering the endoplasmic re
Publikováno v:
Biotechnology journal. 11(4)
The production of biopharmaceutical proteins in plants requires efficient downstream processing steps that remove impurities such as host cell proteins (HCPs) and adventitious endotoxins produced by bacteria during transient expression. We therefore
Autor:
Thomas Rademacher, Rainer Fischer, Juergen Drossard, Holger Spiegel, Markus Sack, Alexander Boes, Stephan Hellwig, Eva Stoger
Publikováno v:
Plant biotechnology journal. 13(8)
The EU Sixth Framework Programme Integrated Project 'Pharma-Planta' developed an approved manufacturing process for recombinant plant-made pharmaceutical proteins (PMPs) using the human HIV-neutralizing monoclonal antibody 2G12 as a case study. In co
Publikováno v:
Journal of Biotechnology. 124:302-311
Plants have been established as an useful production system for commercially relevant proteins. Plant cell cultures show certain advantages compared to field-grown plants. However, one critical drawback for the long-term use of recombinant plant cell
Autor:
Ashok K. Srivastava, Alfredo Ramos-Plasencia, Jochen Büchs, Keyur Raval, Stephan Hellwig, Gunjan Prakash
Publikováno v:
Journal of Bioscience and Bioengineering. 96:16-22
The effect of major nutrients on growth and azadirachtin-related limonoids (AZRL) production in plant cell culture of Azadirachta indica (neem) was studied with the objective to increase the yield of AZRL, one of the major group of pesticidal compoun
Autor:
Rainer Fischer, Frank Emde, Nicole P. G. Raven, Mario Henke, Paul van der Logt, Stephan Hellwig
Publikováno v:
Biotechnology and Bioengineering. 74:344-352
In the last few years the Pichia pastoris expres- sion system has been gaining more and more interest for the expression of recombinant proteins. Many groups have employed fermentation technology in their investi- gations because the system is fairly
Autor:
Alexander Croon, Clemens H. M. Kocken, Nicolas Havelange, Jürgen Drossard, Sophie Houard, Bart W. Faber, Robin Kastilan, Nicole van der Werff, Alan W. Thomas, Hubert Mertens, Marjolein van der Eijk, Richard W. Byrne, Edmond J. Remarque, Stephan Hellwig
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading asexual blood stage vaccine candidate for malaria. In preparation for clinical trials, three Diversity Covering (DiCo) PfAMA1 ectodomain proteins, designed to overcome the intrinsi
Radio frequency impedance spectroscopy (RFIS) is a robust method for the determination of cell biomass during fermentation. RFIS allows non-invasive in-line monitoring of the passive electrical properties of cells in suspension and can distinguish be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d36abc0ddd67e63edf68050d28cff2
https://publica.fraunhofer.de/handle/publica/233600
https://publica.fraunhofer.de/handle/publica/233600