Zobrazeno 1 - 10
of 754
pro vyhledávání: '"Stephan Günther"'
Autor:
Ayodeji Olayemi, Dominik Werner Schmid, Ramona Fleischer, Kerstin Wilhelm, Alexander Christoph Heni, Nadine Mueller-Klein, Lavinia Haikukutu, Elisabeth Fichet-Calvet, Stephan Günther, Simone Sommer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011984 (2024)
West African Mastomys rodents are the primary reservoir of the zoonotic Lassa virus (LASV). The virus causes haemorrhagic Lassa fever and considerable mortality in humans. To date, the role of Mastomys immunogenetics in resistance to, and persistence
Externí odkaz:
https://doaj.org/article/a5bcc3548c90499a8c5ee2e12ce2d4c2
Autor:
Adetunji Samuel Adesina, Akinlabi Oyeyiola, Adeoba Obadare, Joseph Igbokwe, Chukwuyem Abejegah, Patience Akhilomen, Umaru Bangura, Danny Asogun, Ekaete Tobin, Olufemi Ayodeji, Omolaja Osoniyi, Chris Davis, Emma C. Thomson, Meike Pahlmann, Stephan Günther, Elisabeth Fichet-Calvet, Ayodeji Olayemi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTWe phylogenetically compared sequences of the zoonotic Lassa virus (LASV) obtained from Mastomys rodents in seven localities across the highly endemic Edo and Ondo States within Nigeria. Sequencing 1641 nt from the S segment of the virus geno
Externí odkaz:
https://doaj.org/article/daae585ff4ff4b388bd75c191ef90d19
Autor:
Stephanie Longet, Cristina Leggio, Joseph Akoi Bore, Stephanie Key, Tom Tipton, Yper Hall, Fara Raymond Koundouno, Hilary Bower, Tapan Bhattacharyya, N’Faly Magassouba, Stephan Günther, Ana-Maria Henao-Restrapo, Jeremy S. Rossman, Mandy Kader Konde, Kimberly Fornace, Miles W. Carroll
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 2, Pp 304-313 (2023)
Lassa fever virus (LASV) is the causative agent of Lassa fever, a disease endemic in West Africa. Exploring the relationships between environmental factors and LASV transmission across ecologically diverse regions can provide crucial information for
Externí odkaz:
https://doaj.org/article/45154d73b7f74ba986ea9966f3c980a3
Autor:
Sylvanus Okogbenin, Cyril Erameh, Joseph Okoeguale, Osahogie Edeawe, Esele Ekuaze, Kelly Iraoyah, John Agho, Mirjam Groger, Benno Kreuels, Lisa Oestereich, Femi O. Babatunde, Peter Akhideno, Stephan Günther, Michael Ramharter, Till Omansen
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 10, Pp 2060-2063 (2022)
Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of compli
Externí odkaz:
https://doaj.org/article/a804aa399add43bdb7e283df43aac174
Autor:
Raphaëlle Klitting, Liana E. Kafetzopoulou, Wim Thiery, Gytis Dudas, Sophie Gryseels, Anjali Kotamarthi, Bram Vrancken, Karthik Gangavarapu, Mambu Momoh, John Demby Sandi, Augustine Goba, Foday Alhasan, Donald S. Grant, Sylvanus Okogbenin, Ephraim Ogbaini-Emovo, Robert F. Garry, Allison R. Smither, Mark Zeller, Matthias G. Pauthner, Michelle McGraw, Laura D. Hughes, Sophie Duraffour, Stephan Günther, Marc A. Suchard, Philippe Lemey, Kristian G. Andersen, Simon Dellicour
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
It is currently unknown how climate and land use changes could affect the endemic area of Lassa virus, a zoonotic pathogen responsible for Lassa fever. Here, the authors show that by 2070, new regions in Africa will likely become ecologically suitabl
Externí odkaz:
https://doaj.org/article/6f2baa4e42b74416be648772fc0c48a8
Autor:
Ephraim Ogbaini-Emovon, Francis Erah, Emmanuel Friday Osagiede, Chinelo Juliana Nnadi, Yemihan Ogbetere, Ekaete A. Tobin, Danny Asogun, Martha Okonofua, George Akpede, Peter Akhideno, Cyril Erameh, Mojeed Olaitan Rafiu, Wilson Ovienria, Catherina Ephraim-Ogbaini, Chiedozie Ojide, Uche Unigwe, Faith Ireye, Stephan Günther, Sophie Duraffour, Sylvanus Okogbenin
Publikováno v:
International Journal of Occupational Safety and Health, Vol 13, Iss 3 (2023)
Introduction: Healthcare workers (HCWs) are potentially exposed to infection during viral hemorrhagic fever outbreaks. In the wake of 2018, Nigeria experienced an unprecedented surge in cases of Lassa fever (LF), which affected HCWs. To guide infecti
Externí odkaz:
https://doaj.org/article/2152fa8ce3cd46d5a854a49ee18041b4
Autor:
Suzanne Penfold, Ayola Akim Adegnika, Danny Asogun, Olufemi Ayodeji, Benedict N Azuogu, William A Fischer, Robert F Garry, Donald Samuel Grant, Christian Happi, Magassouba N'Faly, Adebola Olayinka, Robert Samuels, Jefferson Sibley, David A Wohl, Manfred Accrombessi, Ifedayo Adetifa, Giuditta Annibaldis, Anton Camacho, Chioma Dan-Nwafor, Akpénè Ruth Esperencia Deha, Jean DeMarco, Sophie Duraffour, Augustine Goba, Rebecca Grais, Stephan Günther, Énagnon Junior Juvénal Prince Honvou, Chikwe Ihekweazu, Christine Jacobsen, Lansana Kanneh, Mambu Momoh, Aminata Ndiaye, Robert Nsaibirni, Sylvanus Okogbenin, Chinwe Ochu, Ephraim Ogbaini, Énagnon Parsifal Marie Alexandre Logbo, John Demby Sandi, John S Schieffelin, Thomas Verstraeten, Nathalie J Vielle, Anges Yadouleton, Emmanuel Koffi Yovo, Enable Protocol authorship group
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283643 (2023)
BackgroundLassa fever (LF), a haemorrhagic illness caused by the Lassa fever virus (LASV), is endemic in West Africa and causes 5000 fatalities every year. The true prevalence and incidence rates of LF are unknown as infections are often asymptomatic
Externí odkaz:
https://doaj.org/article/78e2d262c5864b628c831163c101c26f
Autor:
Tomas Kouba, Dominik Vogel, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, Harry M. Williams, Morlin Milewski, Carola Busch, Stephan Günther, Kay Grünewald, Maria Rosenthal, Stephen Cusack
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The L protein of segmented, negative strand RNA viruses contains the RNA-dependent RNA polymerase essential for virus amplification. Here, the authors report cryoEM structures of the Lassa virus L protein in active, RNA-bound states, and provide mech
Externí odkaz:
https://doaj.org/article/97a04e7215a44a4ebaec52c71bff412e
Autor:
Robert W. Cross, Ira M. Longini, Stephan Becker, Karin Bok, David Boucher, Miles W. Carroll, Janet V. Díaz, William E. Dowling, Ruxandra Draghia-Akli, James T. Duworko, John M. Dye, Michael A. Egan, Patricia Fast, Amy Finan, Courtney Finch, Thomas R. Fleming, Joan Fusco, Thomas W. Geisbert, Anthony Griffiths, Stephan Günther, Lisa E. Hensley, Anna Honko, Ruth Hunegnaw, Jocelyn Jakubik, Julie Ledgerwood, Kerstin Luhn, Demetrius Matassov, Jeffrey Meshulam, Emily V. Nelson, Christopher L. Parks, Roxana Rustomjee, David Safronetz, Lauren M. Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, Christina F. Spiropoulou, Nancy J. Sullivan, Kelly L. Warfield, Daniel Wolfe, Courtney Woolsey, Roland Zahn, Ana María Henao-Restrepo, César Muñoz-Fontela, Andrea Marzi
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10 (2022)
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectiou
Externí odkaz:
https://doaj.org/article/eb16d630ec60444cb74dc537f414a98d
Autor:
Adewale E Adetunji, Magdalene Ayenale, Irene Akhigbe, Lilian O Akerele, Efosa Isibor, Juliet Idialu, Florence O Aideloje, Ekene Emuebonam, Chris Aire, Donatus I Adomeh, Ikponmwosa Odia, Rebecca O Atafo, Martha O Okonofua, Adaugo Owobu, Ephraim Ogbaini-Emovon, Ekaete A Tobin, Danny A Asogun, Sylvanus A Okogbenin, Pardis Sabeti, Christian T Happi, Stephan Günther, Chukwuemeka O Azubuike, Mojeed Rafiu, Angela Odike, Sylvia C Olomu, Michael O Ibadin, Peter O Okokhere, George O Akpede, Prof.
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss , Pp 124-131 (2021)
Objectives: To assess the prevalence of acute kidney injury (AKI), and its impact on outcome in hospitalized pediatric patients with Lassa fever (LF). Methods: We reviewed the presenting clinical and laboratory features and outcomes of 40 successive
Externí odkaz:
https://doaj.org/article/df4807f0549b48508bee2e63d763dc28