Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stephan F. Schlosser"'
Autor:
Kirsten Lauber, Christoph P. Berg, Sebastian Wesselborg, Friedrich Wilhelm Schmahl, Stephan F. Schlosser, Klaus Schulze-Osthoff, Markus Schuler
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:1912-1921
The molecular mechanisms underlying the clinical effects of alpha interferon (IFN) and ribavirin are not understood. Elimination of infected cells occurs in part by cytotoxic T lymphocytes (CTLs) expressing CD95 ligand and thereby attacking target ce
Autor:
Sebastian Wesselborg, Kirsten Lauber, A Rothbart, Christoph P. Berg, Stephan F. Schlosser, Ingo H. Engels, Klaus Schulze-Osthoff, Andrea Renz
Publikováno v:
Cell Death & Differentiation. 8:1197-1206
Although proteases of the caspase family are essential mediators of apoptosis in nucleated cells, in anucleate cells their presence and potential functions are almost completely unknown. Human erythrocytes are a major cell population that does not co
Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosisin vivo
Autor:
Richard A. Flavell, Ravi Hingorani, Timothy S. Zheng, Stephan F. Schlosser, Tao Dao, James L. Boyer, I. Nicholas Crispe
Publikováno v:
Proceedings of the National Academy of Sciences. 95:13618-13623
Both caspase-1- and caspase-3-like activities are required for Fas-mediated apoptosis. However, the role of caspase-1 and caspase-3 in mediating Fas-induced cell death is not clear. We assessed the contributions of these caspases to Fas signaling in
Publikováno v:
Hepatology. 25:284-290
Expression and function of the hepatic Na+/taurocholate cotransporter (ntcp) are down-regulated in several models of experimental cholestasis. To test whether retention and/or depletion of biliary constituents are involved in ntcp regulation, ntcp ex
Autor:
Stephan F. Schlosser, Christoph P. Berg, Sebastian Wesselborg, Michael Gregor, Dorothee K H Neukirchen, Gerburg M. Stein, Costa Papadakis
Publikováno v:
Virology Journal, Vol 6, Iss 1, p 213 (2009)
Virology Journal
Virology Journal
Background Hepatitis C virus (HCV) associated liver diseases may be related to apoptotic processes. Thus, we investigated the role of different HCV proteins in apoptosis induction as well as their potency to interact with different apoptosis inducing
Autor:
James L. Boyer, Tao Dao, Stephan F. Schlosser, Francesco Azzaroli, I. Nicholas Crispe, Ravi Hingorani
Publikováno v:
Hepatology (Baltimore, Md.). 32(4 Pt 1)
Hepatocytes constitutively express CD95 (also called Fas/APO-1) and are therefore potential targets for CD95-ligand (CD95L)-mediated injury. To study this mechanism of cell death in hepatocytes we developed an in vitro model of liver cell apoptosis u
Autor:
Carol J. Soroka, James L. Boyer, Meenakshisundaram Ananthanarayanan, Marco Arrese, Frederick J. Suchy, Dietrich Keppler, Thomas A. Koeppel, Stephan F. Schlosser, Michael Trauner
Publikováno v:
Gastroenterology. 113(1)
BACKGROUND & AIMS: The excretion of various organic anions into bile is mediated by an adenosine triphosphate-dependent conjugate export pump, which has been identified as the canalicular isoform of the multidrug resistance protein (Mrp2). Mrp2 funct
Autor:
Albert Mennone, Michael B. Fallon, Angela D. Burgstahler, Juan C. Sáez, Carlos B. Gonzalez, Michael H. Nathanson, Stephan F. Schlosser
Publikováno v:
From Ion Channels to Cell-to-Cell Conversations ISBN: 9781489917973
Cytosolic Ca2+ (Cai 2+) is an important second messenger in hepatocytes, where it regulates diverse cell functions ranging from bile secretion1 to glucose metabolism2 to apoptosis3. In excitable cell types such as neurons4, 5 and myocytes6, Cai 2+ si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d5d051dcdcfd3a2e58b9bd0970d6a16
https://doi.org/10.1007/978-1-4899-1795-9_27
https://doi.org/10.1007/978-1-4899-1795-9_27
Intercellular communication among certain cell types can occur via ATP secretion, which leads to stimulation of nucleotide receptors on target cells. In epithelial cells, however, intercellular communication is thought to occur instead via gap juncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f8af8d6aec8b26ea90c8e594d3cb99
https://europepmc.org/articles/PMC38535/
https://europepmc.org/articles/PMC38535/
Autor:
Stephan F. Schlosser, Markus Schuler, Sebastian Wesselborg, Christoph P. Berg, Michael Gregor
Publikováno v:
Gastroenterology. 118:A1487