Chlamydia-induced curvature of the host-cell plasma membrane is required for infection

Autor: Johannes H. Hegemann, Katja Mölleken, Agathe Subtil, Stephan F. Lichtenthaler, Sebastian Hänsch, Gido Murra, Karl Köhrer, Ana Rita Furtado, Bastian Dislich, Dominik Spona

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, pp.201911528. ⟨10.1073/pnas.1911528117⟩
Proceedings of the National Academy of Sciences of the United States of America 117(5), 2634-2644 (2020). doi:10.1073/pnas.1911528117
Hänsch, Sebastian; Spona, Dominik; Murra, Gido; Köhrer, Karl; Subtil, Agathe; Furtado, Ana Rita; Lichtenthaler, Stephan F; Dislich, Bastian; Mölleken, Katja; Hegemann, Johannes H (2020). Chlamydia-induced curvature of the host-cell plasma membrane is required for infection. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 117(5), pp. 2634-2644. National Academy of Sciences NAS 10.1073/pnas.1911528117
Proceedings of the National Academy of Sciences of the United States of America, 2020, pp.201911528. ⟨10.1073/pnas.1911528117⟩

Significance We describe a mechanism by which the obligate intracellular pathogen Chlamydia pneumoniae induces curvature of the host-cell plasma membrane and recruits a central component of the endocytotic machinery. We demonstrate that a type III-se

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