Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases

Autor: Valentin Rausch, Andreas Krieg, Jordi Camps, Bianca Behrens, Manfred Beier, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Stephan E. Baldus, Wolfram T. Knoefel, Thomas Ried, Nikolas H. Stoecklein

Publikováno v: BMC Research Notes, Vol 10, Iss 1, Pp 1-9 (2017)

Abstract Background Mortality rates of pancreatic cancer remain high, which is mainly due to advanced disease and metastasis. We hypothesized that genomic copy number alterations are enriched in metastatic cells compared to autologous primary tumors,

Externí odkaz: https://doaj.org/article/e7e345f8b43f4f758660f6f114643278

Supplementary Figure 1 from Protein Expression Profiling in High-Risk Breast Cancer Patients Treated with High-Dose or Conventional Dose–Dense Chemotherapy

Autor: Christopher Poremba, Ulrike Nitz, Helmut E. Gabbert, Michael Burson, Peter J. Wild, Arndt Hartmann, Stephan E. Baldus, Karl-Ludwig Schaefer, Achim Rody, Helene Geddert, Svjetlana Mohrmann, Alexander Herr, Oleg Gluz, Evelyn Ting, Raihanatou Diallo-Danebrock

Supplementary Figure 1 from Protein Expression Profiling in High-Risk Breast Cancer Patients Treated with High-Dose or Conventional Dose–Dense Chemotherapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bda8f20001b36d6f23c68021ddafaea
https://doi.org/10.1158/1078-0432.22440310.v1

High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF

Autor: Andreas-Claudius Hoffmann, Ryutaro Mori, Daniel Vallbohmer, Jan Brabender, Ellen Klein, Uta Drebber, Stephan E. Baldus, Janine Cooc, Mizutomo Azuma, Ralf Metzger, Arnulf H. Hoelscher, Kathleen D. Danenberg, Klaus L Prenzel, Peter V. Danenberg

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 7, Pp 674-679 (2008)

PURPOSE: Pancreatic cancer still has one of the worst prognoses in gastrointestinal cancers with a 5-year survival rate of 5%, making it necessary to find markers or gene sets that would further classify patients into different risk categories and th

Externí odkaz: https://doaj.org/article/3da940ce195c400a9b976fc9a75f8027

Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines.

Autor: Anna C Luca, Sabrina Mersch, René Deenen, Stephan Schmidt, Isabelle Messner, Karl-Ludwig Schäfer, Stephan E Baldus, Wolfgang Huckenbeck, Roland P Piekorz, Wolfram T Knoefel, Andreas Krieg, Nikolas H Stoecklein

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59689 (2013)

Three-dimensional (3D) tumor cell cultures grown in laminin-rich-extracellular matrix (lrECM) are considered to reflect human tumors more realistic as compared to cells grown as monolayer on plastic. Here, we systematically investigated the impact of

Externí odkaz: https://doaj.org/article/fd5fe69b257a456cb73ee98f60d9ee35

Reproducibility of Immunohistochemical Scoring for Epidermal Growth Factor Receptor Expression in Non–Small Cell Lung Cancer: Round Robin Test

Autor: Reinhard Büttner, Anja von Heydebreck, Peter Middel, Stephan Störkel, Stephan E. Baldus, Venâncio Avancini Ferreira Alves, Ilhan Celik, Anthony W. I. Lo, Lina Carvalho, Josef Rüschoff, Włodzimierz T. Olszewski, Keith M. Kerr, Alexander Marx, Marco Volante, Ludger Fink, Wolfram Jochum, Erik Thunnissen, Ralf J. Rieker, Hans Jürgen Grote, Fritz Wrba, Fernando Lopez-Rios, Thierry Jo Molina

Publikováno v: Archives of pathology & laboratory medicine, 137(9), 1255-1261. College of American Pathologists
Ruschoff, J, Kerr, K M, Grote, H J, Middel, P, von Heydebreck, A, Alves, V A, Baldus, S E, Buttner, R, Carvalho, L, Fink, L, Jochum, W, Lo, A W I, Lopez-Rios, F, Marx, A, Molina, T J, Olszewski, W T, Rieker, R J, Volante, M, Thunnissen, E, Wrba, F, Celik, I & Storkel, S 2013, ' Reproducibility of immunohistochemical scoring for epidermal growth factor receptor expression in non-small cell lung cancer: round robin test ', Archives of pathology & laboratory medicine, vol. 137, no. 9, pp. 1255-1261 . https://doi.org/10.5858/arpa.2012-0605-OA

The addition of cetuximab to first-line chemotherapy substantially prolonged survival in patients with advanced non-small cell lung cancer whose tumors expressed high levels of epidermal growth factor receptor (EGFR; immunohistochemistry score of ≥

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8365899fb9d0c78a7f44e70e9feb09fa
https://doi.org/10.5858/arpa.2012-0605-oa